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What can we learn from embryogenesis to increase our understanding of how regeneration of damaged adult lung tissue could be induced in serious lung diseases such as chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and asthma? The local tissue niche determines events in both embryogenesis and repair of the adult lung. Important constituents of the niche are extrace
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The glycosaminoglycan dermatan sulfate (DS) is a well-known activator of heparin cofactor II-dependent inactivation of thrombin. In contrast to heparin, dermatan sulfate has never been prepared recombinantly from material of non-animal origin. Here we report on the enzymatic synthesis of structurally well-defined DS with high anticoagulant activity. Using a microbial K4 polysaccharide and the reco
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Non-typeable Haemophilus influenzae (NTHi) is a Gram-negative human commensal commonly residing in the nasopharynx of preschool children. It occasionally causes upper respiratory tract infection such as acute otitis media, but can also spread to the lower respiratory tract causing bronchitis and pneumonia. There is increasing recognition that NTHi has an important role in chronic lower respiratory
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This report is the account of SBUF project 13209 “Moderniserad dagsljusstandard” (Modernized daylight standard). This is a continuation of the SBUF project 12966 “Förstudie dagsljusstandard” (Pre-study daylight standard) published in 2015. SBUF and the Swedish Energy Agency are the two sources of this project’s funding. The task has been to freely describe and interpret history, day-to-day and fut
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The social differentiation of mobile work is complex. While some people are in a position of control over, and initiate, mobilities, others are captivated by it (Massey 1994). The focus of this WP is transport workers, those who provide mobility: truck drivers, cycle couriers and uber drivers. It is inspired by previous studies of less privileged workers in the power geometry of mobile work: of se
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The home is constituted of materials, cultural meanings and practices (Blunt & Dowling 2006), which means, among other things, that we make home through our domestic practices (Hollows 2008). In an ongoing cultural historical project on home management we are studying practices of domestic paperwork during the 20th century in Sweden. Through interviews with people born before 1940, and the stu