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Environmental Risk Assessment of PFAS in a Swedish Stream - A Case Study of Perstorpsbäcken Integrating Measured Concentrations and Species Sensitivity Distributions

I ett litet skånskt vattendrag hittades förhöjda halter av så kallade ”evighetskemikalier” som kan innebära risker för livet under ytan. Trots att vattnet ser rent ut visar mätningar att påverkan från industri och avloppsvatten är större än vad man tidigare känt till. PFAS är en stor grupp industrikemikalier med mycket goda vatten-, fett- och smutsavvisande egenskaper samt hög kemisk- och värmestFreshwater ecosystems are increasingly threatened by persistent chemical pollutants, including per- and polyfluoroalkyl substances (PFAS), which pose long-term risks to both ecosystems and human health. Small streams downstream of urban and industrial areas are often underrepresented in monitoring programmes, despite their potential vulnerability to PFAS contamination. Furthermore, environmental r

Familial genetic risk for posttraumatic stress disorder : Associations with clinical features

In the present study, the novel family genetic risk score (FGRS) method, a reliable quantification of latent genetic risk, was applied to posttraumatic stress disorder (PTSD) to examine associations between genetic liability and clinical features of PTSD among 3,097,180 individuals in the Swedish national registries. FGRS was calculated based on lifetime PTSD status for first- through fifth-degree

Assessing the Performance of a Proton Exchange Membrane Green Hydrogen Generation System through Stack and Balance of Plant Modeling

The integration of Proton Exchange Membrane electrolyzers into hydrogen generation systems offers significant potential for sustainable energy solutions. Integrating hydrogen production with electricity, heat, and renewable energy sources enhances sustainability. PEM electrolyzers effectively address renewable energy intermittent by converting energy into hydrogen, leveraging their ramp rate and l

Water and counterion structuring around cyclic anionic surfactant micelles in solution

Wide-angle neutron scattering analysed using empirical potential structure refinement (EPSR) was used to investigate how aromatic ring structure influences micelle self-assembly in two anionic surfactants: sodium 4-heptylbenzene sulfonate (SHBS) and sodium 5-heptylfuran-2-sulfonate (SHFS). Both surfactants formed globular micelles in aqueous solutions at 0.2 M but differed significantly in micelle

Climate change will increase forest disturbances in Europe throughout the 21st century

Wildfires, insect outbreaks, and storms cause large pulses of tree mortality. Climate change amplifies these forest disturbances, yet their future magnitude and extent remain uncertain. Here, we simulated future forest disturbance regimes at 100-meter resolution across Europe using a deep learning–based simulation framework. Our results show that forest disturbances will continue to increase throu

Genomic erosion across avian lineages in the context of their evolutionary history

Loss of genetic diversity threatens species survival, yet its dynamics and impacts can vary widely across species depending on their evolutionary histories, life-history traits, and demographic trajectories. To investigate these differences, we analyzed the genomes of 3 species that experienced extreme and well-documented population bottlenecks, the Mauritius parakeet, the Mauritius kestrel, and t

Synovial fluid potentiates local fibroblasts to drive monocyte activation in juvenile idiopathic arthritis

Introduction: Synovial fibroblasts (S-Fib) are recognized as key drivers of joint inflammation in adult arthritis. Moreover, data are limited on the processes driving monocyte activation in oligoarticular juvenile idiopathic arthritis (oJIA). Therefore, we aimed to explore if S-Fib from patients with oJIA induce monocyte activation. Methods: S-Fib were isolated from the synovial fluid (SF) of n =

Testing a Coupled Shoreline and Beach-Dune Model for a Predictive Digital Twin of a Hybrid Dune-Dike System

In recent years, Predictive Digital Twins (PDT) have emerged as a potential tool to monitor and predict the behavior of dynamic systems, including nature-based solutions in natural coastal systems. Here, we test the potential of using a simple, coupled shoreline and beach-dune model as a base for a PDT. The models exchange sediment flux balance information at each time step and recalculate shoreli

Relationship between ultrasound damage score of peripheral entheses and spinal bone formation in long-standing radiographic axial spondyloarthritis

OBJECTIVE: To assess structural changes at peripheral entheses and the association with spinal bone formation in patients with long-standing radiographic axial spondyloarthritis (r-axSpA) overall and stratified by sex. METHODS: Peripheral entheses were examined cross-sectionally using ultrasound (US) in patients fulfilling the modified New York criteria for ankylosing spondylitis (AS) and assessed

The genome sequence of Zethes insularis Rambur, 1833 (Lepidoptera: Erebidae)

We present a genome assembly from a male specimen of Zethes insularis (Arthropoda; Insecta; Lepidoptera; Erebidae). The assembly contains two haplotypes with total lengths of 862.07 megabases and 869.20 megabases. Most of haplotype 1 (99.0%) is scaffolded into 31 chromosomal pseudomolecules, including the Z sex chromosome. Most of haplotype 2 (95.76%) is scaffolded into 31 chromosomal pseudomolecu

Flood impacts on road accessibility and buildings in Gothenburg during a 100-year rainfall event

Urban areas are increasingly exposed to extreme precipitation events, which can disrupt critical infrastructure and damage the built environment. While flood impacts are often assessed separately for buildings or road networks, this study analyses both flood-induced road inaccessibility and building flood risk in Gothenburg using a climate-adjusted 100-year rainfall at both the city scale and the

Ex vivo and in vivo immunomodulation in acute lung injury and lung transplantation

Lung transplantation (LTx) remains the only curative treatment for patients with end-stage lung disease, yet long-term outcomes remain inferior to those of other solid organ transplantations, with a 5-year survival below 70%. Major contributors to this limited outcome include primary graft dysfunction (PGD), the leading cause of early mortality, chronic lung allograft dysfunction (CLAD), and low u