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Many animal species use tools, but human technical engagement is more complex. We argue that there is coevolution between technical engagement (the manufacturing and use of tools) and advanced forms of causal cognition in the human (Homo) lineage. As an analytic tool, we present a classification of different forms of causal thinking. Human causal thinking has become detached from space and time, s

The dramatic increase in accessibility to sequencing technologies has opened new avenues into studying different processes, cells, and animal models. In the amphibian models used for regeneration research, these new datasets have uncovered a variety of information about what genes define the regenerating limb as well as how genes and cells change over the course of regeneration. The accumulation o

Radiogenic isotopes provide an important means towards elucidating Archean crustal evolution. The global Hf and Nd isotope record of Archean crustal fragments has been instrumental to unveiling the history of ancient crustal growth and differentiation. The Rb-Sr system could provide valuable complementary constraints in this regard, as this system is particularly sensitive to magmatic fractionatio

The pathogenic Legionella bacteria are notorious for delivering numerous effector proteins into the host cell with the aim of disturbing and hijacking cellular processes for their benefit. Despite intensive studies, many effectors remain uncharacterized. Motivated by the richness of Legionella effector repertoires and their oftentimes atypical biochemistry, also by several known atypical Legionell

Ruddlesden-Popper perovskites (RPPs) have been demonstrated as a very promising approach for tuning the emission color of perovskite light-emitting diodes (PeLEDs). However, achieving high-performance red PeLEDs with recommendation 2020 color coordinates is still challenging due to the lack of reasonable control over the properties of RPP films. Here, we demonstrate that the judicious selection of

From an early age, humans intuitively expect physical objects to obey core principles, includingcontinuity (objects follow spatiotemporally continuous paths) and solidity (two solid objects cannotoccupy the same space at the same time). These 2 principles are sometimes viewed as deriving from asingle overarching “persistence” principle. Indeed, violations of solidity where one solid object seem-in

Previous biochemical and histochemical studies have suggested that catechol-O-methyltransferase (COMT) is a predominantly glial enzyme in the brain. The aim of this work was to study its localization and molecular forms in primary cultures, where cell types can be easily distinguished with specific markers. COMT immunoreactivity was studied in primary astrocytic cultures from newborn rat cerebral

The evolution of surfaces exposed to an aggressive environment and mechanical load is studied. This is a process of stress corrosion that leads to pitting, crack initiation and growing cracks. In conventional fracture analyses a known or a postulated crack is required. A serious complication is that a large part of the lifetime of a crack or a surface flaw is spent during the initiation of the cra

When discussing choice of methodology in evaluation studies, it is wise to reflect upon organizational considerations concerning contracting, conducting and utilization. Based upon research conducted among social workers in Sweden this paper focuses upon possibilities and problems in knowledge dissemination and usage. Powerful institutions in Sweden are now encouraging knowledge development of soc

he paper discusses how courses in mechanics can be taught to architectural students in such a way that concepts are presented to them in a manner making mechanics an inspiration for the designing process rather than simply imposing limitations on it. In courses of this sort that have been held, emphasis has been placed on the use of software to facilitate an intuitive understanding of physical rel

Kuannersuit Glacier, a valley glacier on Disko Island in west Greenland, experienced a major surge from 1995 to 1998 where the glacier advanced 10.5 km and produced a similar to 65 m thick stacked sequence of debris-rich basal ice and meteoric glacier ice. The aim of this study is to describe the tectonic evolution of large englacial thrusts and the processes of basal ice formation using a multipr

Among the approximately 7,000 cytogenetically abnormal childhood and adult B- and T-lineage acute lymphoblastic leukemias (ALL) published to date, numerous recurring chromosomal aberrations and abnormality patterns have been identified, and it has been clearly shown that the cytogenetic features often correlate closely with specific morphologic, immunophenotypic, and clinical parameters. Thus, kar

Models of eye movement control in natural scenes often distinguish between stimulus-driven processes (which guide the eyes to visually salient regions) and those based on task and object knowledge (which depend on expectations or identification of objects and scene gist). In the present investigation, the eye movements of a patient with visual agnosia were recorded while she searched for objects w

In this study, Large Eddy Simulation (LES) has been used to examine supersonic flow and combustion in a model scramjet combustor. The LES model is based on an unstructured finite volume discretization, using total variational diminishing flux reconstruction, of the filtered continuity, momentum, enthalpy, and passive/reactive scalar equations, used to describe the combustion process. The configura

The purpose of this paper was to assess how the EU chemical regulation, REACH, affected the reform of the U.S. Toxic Substances Control Act. It borrows from theories of policy diffusion and of the EU as a regulatory power, which were used to theorize two causal mechanisms potentially leading to convergence between the European and American chemical regulations, tested using a method of process-tra