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Age-associated and degenerative loss of functional integrity in soft tissues develops from effects of cumulative and subtle changes in their extracellular matrix (ECM). The highly ordered tendon ECM provides the tissue with its tensile strength during loading. As age and exercise collude in the high incidence of tendinopathies, we hypothesized that aged tendons fail due to cumulative damage result

Proton motions in hydrated proton conducting perovskites BaZr(0.90)A(0.10)O(2.95) (A = Y and Sc) have been investigated using quasielastic neutron scattering. The results reveal a localized motion on the ps time scale and with an activation energy of similar to 10-30 meV, in both materials. The temperature dependence of the total mean square displacement of the protons shows an onset of this motio

Ammoxidation of 3-picoline was studied on reduced V-Ti-O catalysts with V6O13 as the major vanadium oxide. The results showed that the initial activity as a function of the TiO2 content reached a maximum at 50–60 mole% TiO2. It is proposed that there is maximum contact between the vanadium and titanium phases at this composition, which results in a weakening of the (VO)3+ surface bond. The selecti

Large and complete glaciotectonic sequences formed by marine-terminating glaciers are rarely observed on land, hampering our understanding of the behaviour of such glaciers and the processes operating at their margins. During the Late Weichselian in western Iceland, an actively retreating marine-terminating glacier resulted in the large-scale deformation of a sequence of glaciomarine sediments. Du

Inference of antibody gene repertoires using transcriptome data has emerged as an alternative approach to the complex process of sequencing of adaptive immune receptor germline gene loci. The diversity introduced during rearrangement of immunoglobulin heavy chain variable (IGHV), diversity, and joining genes has however been identified as potentially affecting inference specificity. In this study,

In this work, we report on the efficient removal of heavy metal ions with nanostructured lithium, sodium and potassium titanates from simulated wastewater. The titanates were obtained via a fast, easy and cost effective process based on extraction of sulfate ions from the crystals of titanyl sulfate and their replacement with hydroxyl groups of NaOH, LiOH and KOH solutions leaving the Ti-O framewo

Ambient air pollution is considered a major environmental health threat to pregnant women. Our previous work has shown an association between exposure to airborne particulate matter (PM) and an increased risk of developing pre-eclamspia. It is now recognized that many pregnancy complications are due to underlying placental dysfunction, and this tissue plays a pivotal role in pre-eclamspia. Recent

In the present study the time-course of DNA fragmentation following insulin-induced hypoglycemia was examined. In situ localization of DNA breaks were studied by the terminal deoxynucleotidyl transferase-mediated biotin- deoxyuridine triphosphate nick-end labelling method, and the temporal profile of DNA-fragmentation by agarose gel electrophoresis. Cell nuclei displayed terminal deoxynucleotidyl

Different phenomena such as complex flow field and heat release by combustion are involved in the heat transfer process in combustion chambers. This paper concerns prediction of heat load and wail temperature in a gas turbine combustor by taking different phenomena into account. Two dimensional axi-symmetric models were used to model the flow field and combustion in a premised combustor with two d

Semiconductor nanowires are nanoscale objects formed by bottom-up synthesis. In recent years their unique properties have been exploited in fields such as electronics, photonics, sensors and the life sciences. In this work, the epitaxial growth of nanowires and their applications were studied. Heteroepitaxial growth of III-V nanowires on silicon substrates was demonstrated. This may enable direct

A technique for scalable spray coating of colloidal CdSeTe quantum dots (QDs) for photovoltaics and photodetector applications is presented. A mixture solvent with water and ethanol was introduced to enhance the adhesive force between QDs and the substrate interface. The performance of the detector reached the highest values with 40 spray coating cycles of QD deposition. The photodetectors without

Coherent tunneling processes of multiple Cooper pairs across a Josephson junction give rise to high harmonics in the current phase relation. In this work, we propose and study Josephson junctions based on semiconductor-superconductor-ferromagnetic insulator heterostructures to engineer nonsinusoidal current-phase relations. The gate-tunability of the charge carriers' density in the semiconductor,

City marketing and convention bureaus value propositions in the post-covid timeThe role of convention bureaus across the world is to market destinations and cities.This paper explores destination marketing in the post pandemic time. It focusses on thevalues that convention bureaus, a key actor in the meetings industry, propose topotential visitors. The concept of value propositions (VPs) is common

This is Part 1 of an article arguing for an extended application of Karl Marx’s insight that the apparent reciprocity of free market exchange is to be understood as an ideology that obscures material processes of exploitation and accumulation. Rather than to confine this insight to the worker’s sale of his or her labor-power for wages, and basing it on the conviction that labor-power is uniquely c

Research on very old people has shown that perceived aspects of home are important for health, but research on such associations in younger cohorts of older people is lacking. The aim of this study was to investigate whether perceived aspects of home were associated with psychological well-being among community-living people aged 67–70. Interview data were collected with 371 individuals living in

The ductility of Al alloys is dictated by the nucleation, growth and coalescence of small internal voids originating from intermetallic particle fracture and from the presence of pre-existing porosity. The ductility is degraded when intermetallic particles are large and clustered. A low ductility adversely impacts both forming operations and the integrity of structural components. Local stirring u

The article applies a micro-sociological approach to investigate civil-military relations in a very concrete form: How do interactions between protesters and security forces shape the development of a conflict? Based on fieldwork in Bahrain and interviews with activists, journalists and opposition politicians, the article analyses the micro-sociological dynamics of how, despite great numbers and m

Throughout the design of a new building it is essential that all involved stakeholders understand, communicate, participate, and collaborate with each other to acquire a high-quality result. To support these shared and creative design processes, this paper presents the design and evaluation of virtual collaborative design environment (ViCoDE) - a new collaborative design system. ViCoDE features se

The dynamical stability of tightly packed exoplanetary systems remains poorly understood. While a sharp stability boundary exists for a two-planet system, numerical simulations of three-planet systems and higher show that they can experience instability on timescales up to billions of years. Moreover, an exponential trend between the planet orbital separation measured in units of Hill radii and th

The Wnt signalling pathway is a central communication cascade between cells to orchestrate polarity and fate during development and adult tissue homeostasis in various organisms. This pathway can be regulated by different signalling molecules in several steps. One of the coordinators in this pathway is Nemo-like kinase (NLK), which is an atypical proline-directed serine/threonine mitogen-activated