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Dyskinesia seen in the off-state, referred as graft-induced dyskinesia (GID), has emerged as a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. Although the mechanism underlying the appearance of GID is unknown, in a recent clinical study the partial 5-HT(1A) agonist buspirone was found to markedly reduce GID in three grafted patients, who showed signifi

Different phenomena such as complex flow field and heat release by combustion are involved in the heat transfer process in combustion chambers. This paper concerns prediction of heat load and wail temperature in a gas turbine combustor by taking different phenomena into account. Two dimensional axi-symmetric models were used to model the flow field and combustion in a premised combustor with two d

This thesis investigates the operational performance of IKEA’s Order-Initiated Flow (OIF) model for the Food Category in the Middle East and North Africa (MENA) region. It examines how extended lead times impact product availability, shelf life, and cost efficiency, and identifies the underlying factors contributing to these challenges. The research aims to evaluate the alignment between the desig

Who can become a foster home? An illumination of the foster home secretaty´s role in the selection process Is it possible for anyone to become a foster parent? What if you are homosexual, highly religious or from a foregin culture; is it even worthwhile to applay? We were curious about if one person´s prejudice can effect wehether a person applaying is approved or not. We interviewed social worke

Syftet med denna studie var att utvärdera säkerhetsmarginalerna som läggs kring ett målorgan (tex prostata) vid extern strålterapi. Resultaten kan senare ligga till grund för reducering av säkerhetsmarginalerna, detta för att skydda strål-känslig frisk vävnad från onödig bestrålning. En delstudie var också att försöka finna ett mönster hos prostatans rörelse vid de inledande behandlingstillfällena"Introduction: This thesis is a study of the margins that are necessary in prostate cancer radio therapy treatment. The aim was to analyse the intrafraction motion of the prostate gland during treatment, by the use of portal imaging, in order to optimize the margin around the prostate gland and spare healthy tissue. One of the purposes was to find a common pattern in prostate movement in the

Syftet med detta examensarbete är att vidga min förståelse för färg som skapande verktyg av arkitektur i rumslighet. Studien fokuserar på olika rumsliga fenomen som kan uppkomma beroende på hur färg samspelar med objekt, ytor och rumslighet. Parallellt med detta identifieras olika verktyg och praktiseras sedan i syfte att hitta sätt för färg att vara med i den tidiga designprocessen. För att samlaThe purpose of this thesis is to broaden my understanding of color as a creative tool of architecture in spatiality. The study will focus on different spatial phenomenons that can arise depending on how color interacts with objects, surfaces and spatiality. Parallel to this, different tools will be identified and then practiced in order to find ways for color to be included in the early design pro

Fjärranalys av insekter med laserljus I detta examensarbete utvecklades ett instrument som använder en bredbandig ljusstråle för fjärranalys av insekter. Tjockleken av en jungfrusländas vinge mättes på 87 m avstånd och med en 4 nm noggrannhet. Insekter spelar en huvudroll i ekosystemet och är avgörande för den biologiska mångfalden. Att urskilja och övervaka var miljontals insekter i våra miljöeInsects play a major role in the ecosystem and are an important factor for biodiversity. Using laser remote sensing to distinguish and monitor the millions of insects in-situ, holds large potential to speed up and improve the otherwise time consuming process of trapping and subsequent analysis. In this work, the spectral analyser for an elastic hyper spectral lidar in the SWIR, with 64 effective s

BACKGROUND: Triticum aestivum (wheat) is one of the world's oldest crops and has been used for >8000 years as a food crop in North Africa, West Asia and Europe. Today, wheat is one of the most important sources of grain for humans, and is cultivated on greater areas of land than any other crop. As the human population increases and soil salinity becomes more prevalent, there is increased pressure

In this work, we report on the efficient removal of heavy metal ions with nanostructured lithium, sodium and potassium titanates from simulated wastewater. The titanates were obtained via a fast, easy and cost effective process based on extraction of sulfate ions from the crystals of titanyl sulfate and their replacement with hydroxyl groups of NaOH, LiOH and KOH solutions leaving the Ti-O framewo

Ambient air pollution is considered a major environmental health threat to pregnant women. Our previous work has shown an association between exposure to airborne particulate matter (PM) and an increased risk of developing pre-eclamspia. It is now recognized that many pregnancy complications are due to underlying placental dysfunction, and this tissue plays a pivotal role in pre-eclamspia. Recent

Background: Mitral valve (MV) and tricuspid valve (TV) apparatus geometry are essential to define mechanisms and etiologies of regurgitation and to inform surgical or transcatheter interventions. Given the increasing use of cardiovascular magnetic resonance (CMR) for the evaluation of valvular heart disease, we aimed to establish CMR-derived age- and sex-specific reference values for mitral annula

The Wnt signalling pathway is a central communication cascade between cells to orchestrate polarity and fate during development and adult tissue homeostasis in various organisms. This pathway can be regulated by different signalling molecules in several steps. One of the coordinators in this pathway is Nemo-like kinase (NLK), which is an atypical proline-directed serine/threonine mitogen-activated

Background: The standard reference region (RR) for amyloid-beta (Aβ) PET studies is the cerebellar grey matter (GMCB), while alternative RRs have mostly been utilized without prior validation against the gold standard. This study compared five commonly used RRs to gold standard plasma input-based quantification using the GMCB. Methods: Thirteen subjects from a test–retest (TRT) study and 30 from a

The thesis work concerns development and application of four versatile nonlinear optical techniques, based on exploiting ultrashort laser pulses, for diagnostic purposes in gases and flames. The four techniques, all laser-based, are two-photon laser-induced fluorescence (TPLIF), hybrid femtosecond/nanosecond (fs/ns) rotational coherent anti-Stokes Raman scattering (fs/ns RCARS), fs-laser-induced g

Background: In patients with chronic obstructive pulmonary disease (COPD), the relationship between short-term bronchodilator reversibility and longer-term response to bronchodilators is unclear. Here, we investigated whether the efficacy of long-acting bronchodilators is associated with reversibility of airflow limitation in patients with COPD with a low exacerbation risk not receiving inhaled co

Aims: Alexithymia has been linked to cardiovascular disease. The aim was to explore whether the immuno-inflammatory variables galectin-3 binding protein (Gal3BP), soluble (s)CD163 and galectin-3 were independently associated with alexithymia, while controlling for known risk factors for cardiovascular disease, such as depression, anxiety, impaired glycemic control, obesity, smoking, and physical i

Introduction: Limited prospective evidence is available to guide selection of first-line maintenance therapy in patients with COPD. This pre-specified analysis of the EMAX trial explored the efficacy and safety of dual-versus mono-bronchodilator therapy in maintenance-naïve and maintenance-treated patients. Methods: The 24-week EMAX trial evaluated lung function, symptoms (including rescue medicat

Integrins are transmembrane receptors that activate signal transduction pathways upon extracellular matrix binding. The integrin-mediated adhesive complex (IMAC) mediates various cell physiological processes. Although the IMAC was thought to be specific to animals, in the past ten years these complexes were discovered in other lineages of Obazoa, the group containing animals, fungi, and several mi

BACKGROUND: Prior research has established a positive association between the single-measured triglyceride-glucose (TyG) index and hypertension. Nevertheless, longitudinal studies addressing the enduring impact of TyG index on incident hypertension are lacking. This study sought to explore the association between cumulative TyG index (cum-TyG) and incident hypertension, especially obesity-related

This article analyses the industrial enterprise of the Dutch-born brothers Abraham and Jakob Momma-Reenstierna and their investments in Sápmi and the upper parts of the Torne River Valley, northern Sweden, during the second half of the seventeenth century. The aim is to explore the driving forces behind the industrial projects of the two brothers in a larger global and colonial context. With inspi