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Background and purpose: Patients with focal cartilage lesions experience functional impairment. Results for biological treatments in the middle-aged patient is poor. Previous studies with focal prosthetic inlay resurfacing have shown a higher risk of conversion to total knee replacement at mid-term follow-up. A novel customized implant (Episealer, Episurf, Stockholm, Sweden) has been proposed to i

Differential equations are an important building block for modeling processes in physics, biology, and social sciences. Usually, their exact solution is not known explicitly though. Therefore, numerical schemes to approximate the solution are of great importance. In this thesis, we consider the temporal approximation of nonlinear, nonautonomous evolution equations on a finite time horizon. We pres

This chapter aims to examine the impact of the international anticorruption agenda on the business and investment climate and legal culture in Uzbekistan. In undertaking this task, I specifically emphasise the daily life of anticorruption laws, policies, and agencies in Uzbekistan in order to understand how domestic institutions and actors perceive, interpret, negotiate, and challenge global antic

Context. To be able to investigate the chemical history of the entire Milky Way, it is imperative to also study its dust-obscured regions in detail, as this is where most of the mass lies. The Galactic Center is an example of such a region. Due to the intervening dust along the line of sight, near-infrared spectroscopic investigations are necessary to study this region of interest.Aims. The aim of

The electronic structure of high-quality van der Waals multiferroic CuCrP2S6 crystals was investigated by applying photoelectron spectroscopy methods in combination with DFT analysis. Using X-ray photoelectron and near-edge X-ray absorption fine structure (NEXAFS) spectroscopy at the Cu L2,3 and Cr L2,3 absorption edges, we determine the charge states of ions in the studied compound. Analyzing the

Isosorbide-5-methacrylate was obtained by enzymatic catalysis with Lipozyme RM IM in a highly regioselective manner in up to 87% yield. The process uses readily available acyl donors (methacrylic anydride or vinyl methacrylate), is easily scalable and chromatography free. Simple extractive workup followed by decoloration and filtration affords the monomer with up to > 99% purity. In addition, the

Formation of metal hydrides is a serious complication that occur when hydride forming metals such as zirconium, niobium, vanadium and magnesium are exposed to long term hydrogen environment. The main concern is that the hydride, as being a brittle material, has very poor fracture mechanical properties. Formation of hydride is associated with transportation of hydrogen along the gradients of increa

Autoantibodies to human pituitary cytosol proteins were determined by immunoblotting in sera from patients with hypopituitarism and their relatives. Reactivity to an M(r) 49 000 protein was significantly more frequent in patients (6/21 (28%) P<0.05) as well as in relatives (10/35 (28%) P<0.02) compared with controls (3/44 (6.8%)). Autoantibodies to this particular protein have previously been dete

The sun is the most prominent source of directional information in the heading direction network of the diurnal, ball-rolling dung beetle Kheper lamarcki. If this celestial body is occluded from the beetle's field of view, the distribution of the relative weight between the directional cues that remain shifts in favour of the celestial pattern of polarised light. In this study, we continue to expl

SeeMe is a pedestrian crosswalk warning system with automatic pedestrian detection that is mounted on crosswalk signs. Amber flashing lights are activated when pedestrians are approaching or crossing the crosswalk. The aim is to attract motorists’ attention, to improve yielding behavior and to reduce conflicts. A before-after study with a matched comparison group has been conducted in the Norwegia

This thesis focuses on the languages of thought of multilingual students writing in English, a non-native language. The study examines which languages are used as languages of thought and what functions these languages serve for year-9 students (age 15-16) in a Swedish high school while writing an essay in English under exam-like conditions. The study sheds detailed light on individual differences

The use of a polar diagram method for describing and evaluating the machinability of Inconel 718 was explored. Five key parameters of the work material, representing the mechanical and physical properties which have strongest influence on its machinability, were employed in the diagrams. These five parameters were integrated into a single polar diagram, used to describe the machinability of Incone

Listeners are constantly trying to predict what the speaker will say next. We concurrently measured the electrophysiological and haemodynamic correlates of syntactic pre-activation, investigating when and where the brain processes speech melody cues to upcoming word order structure. Pre-activation of syntactic structure was reflected in a left-lateralised pre-activation negativity (PrAN), which was

Over the past two centuries, coastal regions have experienced various anthropogenic environmental stressors such as ocean acidification, pollution, warming, and deoxygenation that have impacted benthic marine life. Understanding the severity and potential outcomes of such changes is crucial for supporting effective environmental management strategies.Benthic foraminifera, protists with calcite tes

Background: There are differences in oesophageal cancer care across Sweden. According to national guidelines, all patients should be offered equal care, planned and administrated by regional multidisciplinary team meetings. The aim of the study was to investigate differences between regional multidisciplinary team meetings in Sweden regarding clinical staging and treatment recommendations for oeso

This paper reflects on the work done at a large UK university to redesign assessment procedures in a way that was intended to contribute to an improvement in assessment literacy for staff. Existing practice was reviewed and showed that changes in assessment processes were needed to make the organization of assessment more consistent and more transparent across the institution and to develop staff