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The pressure on businesses to act ethically and to get involved in the development area has increased. At the same time, the strength of sportsas a vehicle for development is highlighted from various worldly respected leaders and organizations. The research maps the emerging field of businesses responsibility, development andsport in Kenya. Fifteen companies, which operate in the Kenyan market, ar
The thesis attempts to assess the role of the OECD Commentaries in tax treaty interpretation process concluded between Non-OECD and OECD states. In order to reach the goal of the thesis the thesis discusses the legal status of the OECD Commentaries under public international law, in particular the interrelation of the Commentaries with the Articles of 31 and 32 of the Vienna Convention. The thesis
Sharenting är ett relativt nytt fenomen som fått stor medial uppmärksamhet de senaste åren. Vårdnadshavare i form av privatpersoner och influensers tenderar att obetänksamt dela bilder och information om sina barn på nätet utan att tänka på vilka konsekvenser delandet kan leda till. Barns rättigheter har stärkts i allmänhet när FN:s Barnkonvention inkorporerades i svensk lagstiftning år 2020. BarnSharenting is a relatively new phenomenon which has received a great deal of media attention in recent years. Guardians in the form of private individuals and influencers tend to carelessly share photos and information about their children online without thinking about the consequences of sharing. Children's rights have been strengthened in general when the UN Convention on the Rights of the C
The war in Ukraine has rocked the international security order with a changed threat picture as a fact. The relationship between China, Russia and the West is complex due to that China agrees with Russia in a common adversary; Western democratic values, while having economic interests in continuing exporting their goods to the West. The united West, including its sanctions against Russia, can put
Climate change is a global issue and a serious threat to the world we live in. The consequences of climate change are devastating. Despite the overwhelming scientific consensus on climate change, studies have shown that politicians and voters of far-right parties are particularly likely to dismiss climate change. People who in various ways go against the research and large amounts of scientific ev
Image and flow cytometry was used to study the nuclear DNA content (ploidy) during the squamous cell carcinogenesis in the esophagus. The present retrospective study comprised 26 surgical specimens of squamous cell carcinomas (SCC) in patients who underwent surgery alone at the Department of Surgery in CHUV Hospital in Lausanne, between January 1992 and December 1999. We analyzed 53 healthy tissue
Rheumatoid arthritis (RA) is a chronic inflammatory disease directed towards peripheral joints. As all common diseases it is associated with several genes and a multitude of environmental factors. In addition, in similarity with most other complex diseases, it is defined only on the basis of clinical signs and symptoms, it is therefore more properly classified as a syndrome rather than a distinct
The effects of carbon dioxide, sodium chloride, and sodium nitrite on type B botulinum neurotoxin (BoNT/B) gene (cntB) expression in nonproteolytic Clostridium botulinum were investigated in a tryptone-peptone-yeast extract (TPY) medium. Various concentrations of these selected food preservatives were studied by using a complete factorial design in order to quantitatively study interaction effects
A key unanswered question in smooth muscle biology is whether phosphorylation of the myosin regulatory light chain (RLC) is sufficient for regulation of contraction, or if thin-filament-based regulatory systems also contribute to this process. To address this issue, the endogenous RLC was extracted from single smooth muscle cells and replaced with either a thiophosphorylated RLC or a mutant RLC (T
Only a small number of protein homologues cause the majority of allergies. There is no consensus structure or other obvious common denominator discriminating the few proteins that are allergens from thousands of other, non-allergenic proteins. By database sequence homology searching, we here show that to date known allergen sequences have no or few bacterial homologues, in contrast to randomly sel
Lipid A (a hexaacylated 1,4' bisphosphate) is a potent immune stimulant for TLR4/MD-2. Upon lipid A ligation, the TLR4/MD-2 complex dimerizes and initiates signal transduction. Historically, studies also suggested the existence of TLR4/MD-2-independent LPS signaling. In this article, we define the role of TLR4 and MD-2 in LPS signaling by using genome-wide expression profiling in TLR4- and MD-2-de
We present rock magnetic and palaeointensity data from Holocene Icelandic lava flows, including historical and pre-historical lavas. Susceptibility versus temperature measurements indicate that the magnetic mineralogy is dominated by primary titanomagnetite that have experienced variable degrees of high-temperature oxidisation. The analyses also demonstrate that virtually all studied samples are t
The size of the anisotropic domains in a lyotropic liquid crystal is estimated using a new protocol for diffusion NMR. Echo attenuation decays are recorded for different durations of the displacement-encoding gradient pulses, while keeping the effective diffusion time and the range of the wave vectors constant. Deviations between the sets of data appear if there are non-Gaussian diffusion processe
Bet-hedging is defined as a strategy that reduces the temporal variance in fitness at the expense of a lowered arithmetic mean fitness. After a few technical points, we will here argue that this definition of bet-hedging is badly suited for models with density- and/or frequency-dependent fitness. A strict interpretation cannot be employed; possibly, a modified definition is necessary.
Side-chain carboxyl and carbonyl groups play a major role in protein interactions and enzyme catalysis. A series of C-13 relaxation experiments is introduced to study the dynamics of carboxyl and carbonyl groups in protein side chains on both fast (sub-ns) and slower (mu s-ms) time scales. This approach is illustrated on the protein calbindin D-9k. Fast dynamics features correlate with hydrogen- a
