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Construction of a genetic linkage map of the laboratory rat, Rattus norvegicus, establishes the rat as a genetic model. Allele sizes were reported for 432 simple sequence length polymorphisms (SSLPs) genotyped in 12 different substrains belonging to nine different inbred strains of rats. However, these nine strains represent only a fraction of the more than 140 inbred strains available. If allele
The rate of removal of phosphatidylethanolamine and phosphatidylcholine from the plasma of rats treated with antiserum to hepatic lipase was measured. The hepatic lipase antiserum was injected intravenously into animals prior to injection of 32P-labeled chylomicrons or 32P-labeled high density lipoproteins. In experiments in which 32P-labeled chylomicrons were injected, antiserum treatment inhibit
The digital cellular systems era started about thirty years ago with the release of the first digital cellphones. These first digital cellphones were very different from today’s slim and esthetic cellular pocket computers. They were not mass-produced in million units a day, and they were designed for radio performance rather than appearance. Today, all components are integrated inside the mobile p
The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in recent decades: treatment decisions remain challenging in clinical practice, without a specific therapeutic target beyond the relief of symptoms as the most important goal. In view of this scenario, the European League Against Rheumatism (EULAR) promoted and supported an international collaborative study (EULAR S
Acquired angioedema due to C1-inhibitor (C1INH) deficiency (AAE) is caused by secondary C1INH deficiency leading to bradykinin-mediated angioedema episodes. AAE typically presents in adulthood and is associated with B cell lymphoproliferation. Anti-C1INH autoantibodies (antiC1INHAbs) are detectable in a subset of AAE cases and considered a hallmark of the disease. When free antiC1INHAbs and malign
The Shortest Vector Problem (SVP) is one of the mathematical foundations of lattice based cryptography. Lattice sieve algorithms are amongst the foremost methods of solving SVP. The asymptotically fastest known classical and quantum sieves solve SVP in a $d$-dimensional lattice in $2^{\const d + \smallo(d)}$ time steps with $2^{\const' d + \smallo(d)}$ memory for constants $c, c'$. In this work, w
Purpose: To examine the effects of Treatment Foster Care on youth with serious behavior problems. Method: Included studies are controlled trials with high or medium quality, published between 1990 and September 2017. The control group consists of youth with serious behavior problems in group care, and the follow-up time was at least 12 months. The review also examines ethical and economic aspects.
MOTIVATION: Transcription factors (TFs) are key regulators of gene expression, and can activate or repress multiple target genes, forming regulatory units, or regulons. Understanding downstream effects of these regulators includes evaluating how TFs cooperate or compete within regulatory networks. Here we present RTNduals, an R/Bioconductor package that implements a general method for analyzing pa
Purpose: Current approaches to sustainability science and education focus on (assessing and addressing) the external world of ecosystems, wider socio-economic structures, technology and governance dynamics. A major shortcoming of such approaches is the neglect of inner dimensions and capacities (which constrains education for sustainability as an end), and a limited capacity to facilitate reflecti
This study assesses the impacts of the floods in early 2011 in the Northern Cape Province in South Africa and focuses especially on the small town Keimoes located on the major Orange River. During this period 33 municipalities in 7 out of the country’s 8 provinces were declared as disaster areas due to widespread flooding. In Keimoes and the Northern Cape Province the flood impacts were widespread
This thesis is based on the two months I spent in Bolivia doing applied cultural analysis for a nongovernmental organization (ECAM) that works for women empowerment and gender equality. My intention is to explore the relationship between academia and activism by focusing on the approaches that have been pointed out as counterproductive in the struggle for gender equality. Specifically, the objecti
The thesis explores the possibilities of the Swedish government to assure effective waste collection policies for mercury-containing gas-discharge lamps (GDL) in the context of phase-out of incandescent light bulbs. The study includes review of the waste collection, the waste collection evaluation, policy review and policy analysis. The specific analytical tools applied include Lindhqvist’s policy
Ett första steg i arbetet att uppskatta kolflödet mellan landbaserade ekosystem och atmosfären är att så precist som möjligt analysera kvantiteten ovanjordisk biomassa. LiDAR teknologi har i detta avseende visat sig vara ett värdefullt verktyg. Det överlöpande målet med denna studie är att utveckla en förenklad metod, baserad på fjärranalys, för att uppskatta ovanjordisk biomassa för individuella As a first step in the assessment of carbon flux between the terrestrial environment and the atmosphere it is important to accurately quantify the carbon stock of forest ecosystems. LiDAR technology, in this respect, has proved to be a valuable tool, able to provide accurate estimates of aboveground biomass (AGB). The overall goal of this study was to develop a simplified method for assessing AGB
The Low Energy Beam Transport, LEBT, is the _rst part of the European Spallation Source accelerator, the ESS linac, that is currently under construction in Lund. The LEBT section, that will be installed and commissioned in early 2018, has the purpose of focusing and steering the low-energy proton beam that enters directly from the ion source. For simulation of the beam dynamics in the LEBT, ESS us
Parkinson’s disease (PD) is considered one of the most frequent neurodegenerative disorders amongst elderly people. PD leads to loss of dopaminergic neurons in substantia nigra of the brain giving symptoms such as slowness of movement and dementia. PD brains have been found to contain accumulations of a protein named alpha‐synuclein (α‐syn). Additional to its aggregation propensity in PD it is als
