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Photoacoustic imaging (PAI) is a novel hybrid imaging technique that combines the advantages of optical and ultrasound imaging to produce hyperspectral images of the tissue. The feasibility of measuring oxygen saturation (sO2) with PAI has been demonstrated pre-clinically, but has limited use in humans under conditions of ischemia and reperfusion. As an important step towards making PAI clinically
Developmental hematopoiesis differs from adult and is far less described. In the developing embryo, waves of lineage-restricted blood precede the ultimate emergence of definitive hematopoietic stem cells (dHSCs) capable of maintaining hematopoiesis throughout life. During the last two decades, the advent of single-cell genomics has provided tools to circumvent previously impeding characteristics o
Voice problems are common among workers in occupations with high demands on oral communication. For sustaining vocal health, it is important to find efficient ways for how to reduce strain on the voice at work, and one way to do so is optimizing the room acoustics for communication. However, to date we do not know enough about what kind of room acoustic conditions that support voice and speech mos
Understanding metabolic processes of soil fungi is essential for elucidating their ecological roles in biogeochemical cycles and responses to emergent environmental stressors. Here, we demonstrate the potential of using stable isotope probing Raman (SIP-Raman) microspectroscopy in microfluidics technology-based soil chips to trace glucose metabolism rates and stress responses in laboratory grown f
Wetlands are often constructed to counteract eutrophication or brownification of downstream waters, although our understanding of their differences in efficiency and effects is still scarce. Therefore, we here used the upper and lower 95% confidence limits of the average retention capacity of 11 wetlands to represent efficient and inefficient wetlands, respectively. We then modelled future scenari
Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest malignancies and potentially curable only with radical surgical resection at early stages. The tumor microenvironment has been shown to be central to the development and progression of PDAC.A better understanding of how early human PDAC metabolically communicates with its environment and differs from healthy pancreas could help improve
This report presents showcases of active teaching and learning in spatial data infrastructure education in the SPIDER partner universities. It includes detailed descriptions of the practices that have been implemented, as well as the results of the evaluation of the practices from an active teaching learning perspective.
This report looks at different methods of active teaching and learning and the application of these methods at the partner universities of the SPIDER project. Different methods of on-campus and online teaching are presented and reports on experiences in their application at the partner universities are discussed. In combination with the results from Intellectual Output (IO) 4, this results in best
In recent years, shared freight systems have emerged in many cities as a new modality of freight transportation. However, little attention has been paid to the impact of a city's socioeconomic status on the characteristics of a shared freight network. To fill this gap, in this study, the structural characteristics of an intra-urban shared freight network are measured from the perspective of comple
In recent years, shared micro-mobility services (e.g., bikes, e-bikes, and e-scooters) have been popularized at a rapid pace worldwide, which provide more choices for people’s short and medium-distance travel. Accurately modeling the choice of these shared micro-mobility services is important for their regulation and management. However, little attention has been paid to modeling their choice, esp
Shared electric scooters (e-scooters) have been rapidly growing in popularity across Europe over the past three years, which can bring various environmental and socioeconomic benefits. However, how to further improve the usage efficiency of shared e-scooters is still a major concern for micro-mobility operators and city planners. This paper proposes a machine learning based approach to predict the
Background: The WHO and the World Bank ask countries to report the national volume of surgery. This report describes these data for Sweden, a high-income country. Methods: In an 8-year population-based observational cohort study, all inpatient and outpatient care in the public and private sectors was detected in the Swedish National Patient Register and screened for the occurrence of surgery. The
Rhombomys opimus (R. opimus), a social rodent, is the main reservoir host for zoonotic cutaneous leishmaniasis (ZCL) in most parts of the Middle East and central Asia. The difficulties in monitoring rodent population patterns have hindered the effective application of preventive measures of ZCL. This study presents a spatially explicit agent-based simulation model of R. opimus behaviors that is in
A major problem in CTG analysis is that detectionof a suspicious pattern in short intervals so that one can reducethe damage caused by a delay of an automatic monitoringsystem. In this paper, we aim for improving intrapartumsurveillance based on signal processing and machine learningtechniques. We evaluate a classification method on a real dataset.
This paper estimates the impact of university education on medical care use and its income related inequality. We do this by exploiting an arbitrary university eligibility rule in Sweden combined with regression discontinuity design for the years 2003-2013 for students who graduated 2003-2005. We find a clear jump in university attendance due to university eligibility. This jump coincides with a p
Droplets are sophisticated micro-compartments crucial for lab-on-a-chip and bio-medical applications. There have been significant efforts towards generating monodisperse droplets as the uniformity of droplets affects performance. Recently, we introduced a new method to continuously reform existing emulsions improving monodispersity in an ultrasound-actuated microcavity via a trap-coalesce-split me
