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Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i

Museum Stobaeanum included a collection of artefacts, originally labeled ”artificialia”. It consisted primarily of ethnographic objects from Asia, North and South America, Russia, Siberia, Greenland and Lapland, but also Classical antiquities, Nordic antiques, curious European works of art, as well as scientific instruments and models. Museum Stobaeanum included a comparatively small collection of

https://www.historiskamuseet.lu.se/stobaeus-project/artefacts - 2026-04-29

Lundblad A-M, Hansson K. Relational problems and psychiatric symptoms in couple therapyInt J Soc Welfare 2005: 14: 256 -264 c Blackwell Publishing, 2005.This article describes couples attending family counselling in Sweden. The study group is compared with clinical groups and non-clinical groups. Self-rating instruments were com-pleted by 317 women and 312 men to evaluate the following: marital sa

Microsoft Word - SÄRSKILT TILLSTÅND Efternamn, tilltalsnamn/Last name, first name Personnummer / Swedish personal number (or date of birth) Bostadsadress/Home address Postnummer, ortnamn, land/Post code, city, country Telefon/Phone number E-postadress/E-mail address Antagen till forskarutbildning vid/Admitted to PhD Programme at Universitet eller högskola/University Land/Country Ansökan avser kurs

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/sarskilt-tillstand-forskarutbildning_interaktiv_v4.pdf - 2026-05-01

Microsoft Word - SÄRSKILT TILLSTÅND Efternamn, tilltalsnamn/Last name, first name Personnummer / Personal identity number (or date of birth) Bostadsadress/Home address Postnummer, ortnamn, land/Post code, city, country Telefon/Phone number E-postadress/E-mail address Antagen till forskarutbildning vid/Admitted to PhD Programme at Universitet eller högskola/University Land/Country Ansökan avser kur

https://www.soclaw.lu.se/en/sites/soclaw.lu.se.en/files/2023-06/external%20PhDs,%20Permission%20to%20particiapte%20in%20PhD%20courses%20application.pdf - 2026-05-01

NGEA01_2017_resultat NGEA01_HT17_v2 Respondents: 27 Answer Count: 19 Answer Frequency: 70.37 % Do you think that the aim, as described above, has been reached well in this  course? (1=Not at all; 5=Yes, completely)    Do you think that the aim, as described above, has  been reached well in this course? (1=Not at all; 5=Yes, completely) Number of  Responses 1 0 (0.0%) 2 0 (0.0%) 3 2 (10.5%) 4 12 (6

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/ngea01_2017.pdf - 2026-05-01

Guidelines for Purchasing at Lund University REGULATORY DOCUMENT COVER PAGE Guidelines for Purchasing at Lund University Type of regulatory document: Guidelines Definition of the type of regulatory document: Guidelines establish how someone must or should act in the area covered by the guidelines. A “must” rule is to be complied with, whereas the nature of a “should” rule is more of a strong recom

https://www.staff.lu.se/sites/staff.lu.se/files/2024-12/guidelines-for-purchasing-at-lund-university.pdf - 2026-05-01

On this page, you will find information about the different types of authorisation for the W3D3 registration system. You can also read about which training courses are compulsory in order to obtain authorisation. There are two types of authorisation in W3D3: Official and Registrator. This page describes what you can do and view in the system with the different authorisations and what responsibilit

https://www.staff.lu.se/support-and-tools/records-management/registration-documents/authorisation-w3d3-registration-system - 2026-04-30

Purpose: This study aims to analyse how the founder as brand concept can affect Customer Based Brand Equity. The research aims to contribute insights on how founder representation can strengthen or weaken brand perception among consumers. Methodology: This research follows a quantitative, abductive design. Primary data were collected through a semi-structured focus group interview and secondary da

Established ecological theory has focused on unitary organisms, and thus its concepts have matured into a form that often hinders rather than facilitates the ecological study of modular organisms. Here, we use the example of filamentous fungi to develop concepts that enable integration of non-unitary (modular) organisms into the established community ecology theory, with particular focus on its sp