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Acetylcholine release in the frontal cortex of awake rats after acute or chronic lesions of the nucleus basalis magnocellularis and grafting of cholinergic-rich basal forebrain tissue was studied by in vivo microdialysis. Three to four weeks and five months after a unilateral quisqualic acid lesion of the nucleus basalis, and five months after lesion and cortical implantation of a basal forebrain

Main recommendations: Endoscopic mucosal resection (EMR) is the standard of care for the complete removal of large (≥ 10mm) nonpedunculated colorectal polyps (LNPCPs). Increased detection of LNPCPs owing to screening colonoscopy, plus high observed rates of incomplete resection and need for surgery call for a standardized approach to training in EMR. 1 Trainees in EMR should have achieved basic co

The main goal of this thesis has been to investigate the interaction of the intrinsically disordered peptide Histatin 5 (Hst5), with phospholipid bilayers, using a mixture of experimental and computational techniques, such as, small- angle X-ray scattering, circular dichroism, neutron reflectometry, quartz-crystal microbalance with dissipation monitoring, atomistic molecular dynamics simulations, The main goal of this thesis has been to investigate the interaction of the intrinsically disordered peptide Histatin 5 (Hst5), with phospholipid bilayers, using a mixture of experimental and computational techniques, such as, small- angle X-ray scattering, circular dichroism, neutron reflectometry, quartz-crystal microbalance with dissipation monitoring, atomistic molecular dynamics simulations,

The purpose of this study was to evaluate 10 process-based terrestrial biosphere models that were used for the IPCC fifth Assessment Report. The simulated gross primary productivity (GPP) is compared with flux-tower-based estimates by Jung etal. [Journal of Geophysical Research 116 (2011) G00J07] (JU11). The net primary productivity (NPP) apparent sensitivity to climate variability and atmospheric

The kinetics and mechanism for substitution reactions on tetraaquapalladium(II) by an extended series of thioethers, a great number of carboxylic acids, and olefins have been studied by use of UV-VIS, stopped-flow, and high-pressure stopped-flow spectrophotometry and NMR spectroscopy. Second-order rate constants k and activation parameters (activation enthalpies, entropies, and volumes) for format

Popular Abstract in Swedish I denna avhandling belyses varför och hur frågan om arbetarnas bildning blev ett led i såväl borgerlighetens som arbetarklassens formering under andra hälften av 1800-talet. Arbetet utgår från ett teoretiskt perspektiv som bl a innebär att människor aktivt skapar sin klassidentitet i sina vardagliga liv. Undersökningens tyngdpunkt ligger på jämförande analyser mellan sThis dissertation deals with the question of why and how the issue of workers' education came to be part of both bourgeois and working class formation during the second half of the 19th century and how it contributed to the shaping of new social relations. The theoretical perspective is based on the concept of hegemony indicating that a leading class has to establish and maintain its leadership by

Popular Abstract in Swedish För att vi människor ska kunna upprätthålla balansen och utföra rörelser behöver vi ett komplext styrsystem som kontinuerligt kontrollerar och samordnar kroppens rörelser. Detta styrsystem, som kallas postural kontroll, får sin information från synen, balanssinnet (vestibularisorganen), led-muskelsinnet (proprioception) och receptorer i huden (mekanoreceptorer). Om någoThe ability to obtain correct balance control information and adjust motor performance appropriately are essential elements in effective postural control. However, functional disorders may affect the reliability of receptor information and ability to carry out corrective motions needed to maintain balance. This emphasizes the importance of rapid and accurate adaptation processes that can optimize

The era when customers bought what companies produced is long gone. The situation is now reversed and companies must produce what customers want; while the customers' preferences are, furthermore, becoming increasingly diverse. This has forced companies to adopt a new mode of thinking in order to survive. The strategy, by necessity, has become to manufacture flexibly. This thesis focuses on stra

Popular Abstract in Swedish Avhandlingen består av fem fristående uppsatser som utnyttjar tidsserieanalys för studerande av några olika makroekonomiska frågor. I kapitel två, tre och fyra används s.k. vektorautoregressiva (VAR) modeller för att studera privat konsumtionsbeteende i Sverige. Enligt den permanenta inkomst hypotesen väljer individerna sin konsumtion med hänsyn till sin långsiktiga ellAdvances in time series analysis during the last two decades have stimulated research in a number of areas in macroeconomics. This thesis is a compilation of five essays using cointegrated vector autoregressive (VAR) models, unit root tests and regime switching models to investigate the behavior of private consumption, public debt and the real exchange rate. Chapter two explores the empirical evi

Popular Abstract in English In earlier times, patients suffering from mental illness were nursed in large psychiatric institutions, often experiencing extended, sometimes life-long, institutionalization. These institutions were responsible for the patients during the entire course of their lives and provided housing as well as activities along with the care. The patients’ social contacts were mainThe overall aim of this thesis is to 1) investigate the prevalence of stigmatizing experiences and beliefs of devaluation and discrimination among persons with mental illness, and 2) to investigate the relationship between beliefs of devalua¬tion/¬discrimination, rejection experiences and sociodemographic/clinical patient characteristics, social networks, self esteem, empowerment and subjective qu

Popular Abstract in Swedish Syftet med avhandlingen är att studera och analysera en historisk epok och dess människor genom deras materiella kultur och hur de sociala relationerna har manifesterats i rummet. Som fokus fungerar den medeltida biskopsstaden Linköping, en plats som skiftat utseende, funktion och betydelse genom olika perioder, men hela tiden med starka ideologiska uttryck. Linköping Is it possible to understand a society and a certain place that is long since gone? The aim of this thesis is to study and analyse a historic period and its people through the remains of their material culture, the social relations and how these were materialized in an urban setting. The main subject of the empirical study, the medieval episcopal town of Linköping, has shifted out-look, function a

This dissertation is about the antagonistic conceptions of men’s violence against women – rape, incest and physical assault – as has been expressed by different actors in Sweden from 1975 – 2000. Mainly, my interest lies in how and why these conceptions have been articulated. During the studied period the attention to men’s violence against women as a question of gender, has grown remarkably. For

Popular Abstract in Swedish Den kemiskt enkla föreningen cis-[PtCl2(NH3)2)] (cisplatin) används för behandling av vissa cancerformer. Föreningen är i allmänhet giftig för kroppens organ och kroppen utvecklar resistens, vilket begränsar den kliniska effektiviteten. Generellt anses det att den önskade anticancer-effekten fås som ett resultat av inbindningen av platinakomplexen till DNA, medan interaIn this thesis reductions of model and anticancer active Pt(IV) complexes with thiols and ascorbic acid and substitution reactions of cisplatin and model Pt(II) complexes with S-donor nucleophiles (rescue agents) have been investigated using stopped-flow and UV/VIS spectrophotometry. Glutathione (GSH) reduction of the anticancer active Pt(IV) compounds t- and c-[PtCl4(cha)(NH3)] (cha = cyclohexyla

This report highlights the conditions for young people trying to establish themselves in the labour market in the Nordic countries. The aim has been to examine similarities and differences with regard to specific aspects of the welfare systems with a focus on upper secondary school level and political initiatives in the labour market. The passage of students through upper secondary school, transit

1. Salmeterol is a potent, selective and long acting beta 2-adrenoceptor agonist. In vitro, salmeterol exerts 'reassertion' relaxation of airways smooth muscle. Reassertion relaxation refers to the capacity of salmeterol to cause repeated functional antagonism of induced contraction when airway smooth muscle is intermittently exposed to, then washed free from, beta-adrenoceptor antagonists such as

Popular Abstract in Swedish Protontransport är en fundamental process som finns i många naturliga system, liksom i många tekniska applikationer, såsom bränsleceller, smarta fönster och olika typer av sensorer. Bränslecellsteknologi anses vara miljövänlig eftersom bränsleceller inte begränsas av Carnot-cykeln och omvandlar effektivt kemisk energi till elektrisk energi som sedan kan användas till atProton transport is a fundamental process that can be found in many systems in nature, as well as in technical devices, such as fuel cells, electrochromic devices and various types of sensors. Fuel cell technology is considered as environmentally friendly because fuel cells are not limited by the Carnot cycle, and efficiently converts chemical energy into electrical energy which can be used for po

1. The survey has mainly concentrated on the following items: the false alarm problem, the problem of the fire not being detected due to the fact that pre-fire heating and ventilation dominate flow inside the compartment, a description of detector sensitivity to fire signatures. engineering design methods for the siting of detectors. 2. The statistical as well as practical experience suggests that

The aim of this thesis was to characterize a personal denuder/filter sampler for isocyanate aerosol and to study the emission of airborne particles from the interaction between studded tires and pavements. Both types of aerosols are highly relevant for health studies in public and occupational environments. The adverse health effects of airborne isocyanate exposure are well known in the occupatio

This report summarizes 28 case studies addressing the common interest for indicators in case studies in Nordic and Baltic countries and is distributed to different building types – Benchmarking systems and indicators (4 case studies) – Offices (7 case studies) – Housing (8 case studies) – School and nursery (5 case studies) – Shopping centres (3 case studies) – Hospital (1 case studies) There are

The content of this thesis consists of two parts. For the first part, size and crystallographic orientational influence on the elastic properties of bcc nanowires and films have been studied through static molecular simulations. In order to explicitly account for surface effects, the concept of surface free energy has been employed. Comparisons between continuum mechanical calculations and results