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Problem discussion: To be more competitive, Trading Area Wood is working on developing their suppliers in efficiency projects. However, they find it hard to motivate their suppliers to take part in the projects. Therefore, they need a way to show the suppliers the positive effects of participating in the efficiency projects. Moreover, Trading Area Wood has troubles to predict the economical outcom
Genom att skapa och använda ett ramverk för att undersöka avgöranden från Mark- och miljööverdomstolen har jag analyserat om partiskhet är ett relevant skäl för domstolen att inte lita på partssakkunnig i miljöprocessen. Underlag för analysen är ett stort antal rättsfall från Mark- och miljööverdomstolen där argumentation om partiskhet förekommer. Det finns anledning att skilja mellan två olika säBy creating and using a framework to examine the decisions of Mark- och miljööverdomstolen I analyzed if bias is a valid reason for the court not to trust an expert hired by a party in the environmental process. Material for the investigation is a large number of cases from Mark- och miljööverdomstolen where arguments of bias exist. There is reason to distinguish between two different ways in whic
Popular Abstract in Swedish Det blir allt vanligare att man ersätter förlorade och skadade kroppsdelar med ett biomaterial (vanligtvis ett metall eller polymer implantat). Exempel på vanliga användningsområden är; suturer, kärl, hjärtklaffar, pacemakers, katetrar, ledproteser, fixationsskruvar för skelett och konstgjorda tänder samt kapslar för långsam frisättning av medicin. Trots det rutinmässigThe biological response to different implanted biomaterials vary. The relative importance of factors in the material and host for this variation are at present incompletely known. The variation in the cellular response to specific proteins and the rapid adsorption of proteins to surfaces exposed to biological environments has created the hypothesis that the cellular interactions with biomaterials
The base of the world economic pyramid, generally called the base of the pyramid (BoP), consists of four billion people with average daily income of four dollars. Over the past several years, the design and development of products and services for BoP markets has been investigated by several authors from different disciplines. While some authors suggest a systems approach to design and develop pro
Background: T1D and AITD are autoimmune disorders commonly occurring in the same family and even in the same individual. The genetic contribution to these disorders is complex making uncovering of susceptibility genes very challenging. The general aim of this study was to identify loci and genes contributing to T1D/AITD susceptibility. Our strategy was to perform linkage and association studies in
This thesis explores office paper as a medium between 1920 and 1960 in Sweden. During this period, paper was muchdebated due to the number of standards that were implemented. These standardstransformed paper, making it a modern medium in many different ways. The aim ofthe present thesis is to analyze how office paper was reshaped to solveproblems regarding production, reproduction, circulation and
Children spend a large percentage of their day with their classmates in school. Classmates are not only co-workers, but also individuals interacting socially as friends. The understanding of group affiliation and friendship interaction in school is of great importance to social work in school because of its implications on children’s wellbeing and academic performance. Several studies show that soChildren spend a large percentage of their day with their classmates in school. Classmates are not only co-workers, but also individuals interacting socially as friends. The understanding of group affiliation and friendship interaction in school is of great importance to social work in school because of its implications on children’s wellbeing and academic performance. Several studies show that so
Background: Malignant melanoma and non-melanoma skin cancers are among the fastest increasing malignancies in many countries. With the help of new tools, such as teledermoscopy referrals between primary health care and dermatology clinics, the management of these patients could be made more efficient. Objective: To evaluate the diagnostic agreement and interobserver concordance achieved when asses
In atherogenesis, free oxygen radicals cause a lipid peroxidation of apoB100-containing lipoproteins in the blood, at the blood–endothelium-interface and in the subendothelial space. These lipoproteins easily aggregate, bind to their receptor heparan sulfate proteoglycan and calcify to arteriosclerotic nanoplaques (ternary complexes). Nanoplaque formation was measured by ellipsometry, both in vitr
Knee injury increases the risk of developing knee osteoarthritis (OA). Recent evidence suggests involvement of oxidative stress induced by inflammation and bleeding in the joint. This study investigates the role in this process of α1-microglobulin (A1M), a plasma and tissue antioxidant protein with reducing function, and heme- and radical-binding properties. We studied matched knee synovial fluid
The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in recent decades: treatment decisions remain challenging in clinical practice, without a specific therapeutic target beyond the relief of symptoms as the most important goal. In view of this scenario, the European League Against Rheumatism (EULAR) promoted and supported an international collaborative study (EULAR S
Master protocols combine several sub-trials, each with their own research objectives, which is usually presented as one single clinical trial application. Master protocols have become increasingly popular in oncology and haematology, as either basket, umbrella, or platform trials. Although master protocols are intended to accelerate drug development and to reduce futility, their use poses challeng
Culture and discourses affect our understanding of the archive in the digital environment: preconceptions, norms, and practices developed in a paper-based administration colour and limit perceptions of digital archives. It can be difficult to reimagine the archive in the context of e-government and the networked environment, where the complexity of archival issues increases. This is a global probl
In molecular neurobiology, perhaps no molecule has been as thoroughly examined as Alzheimer's beta-amyloid precursor protein (beta-APP). In the years since the cDNA encoding beta-APP was cloned, the protein has been the subject of unparalleled scrutiny on all levels. From molecular genetics and cellular biology to neuroanatomy and epidemiology, no scientific discipline has been left unexplored - a
In molecular neurobiology, perhaps no molecule has been as thoroughly examined as Alzheimer's beta-amyloid precursor protein (betaAPP). In the ten years since the cDNA encoding betaAPP was cloned, the protein has been the subject of unparalleled scrutiny on all levels. From molecular genetics and cellular biology to neuroanatomy and epidemiology, no scientific discipline has been left unexplored -
Importance: Prognostication of neurologic outcome after cardiac arrest is an important but challenging aspect of patient therapy management in critical care units. Objective: To determine whether serum neurofilament light chain (NFL) levels can be used for prognostication of neurologic outcome after cardiac arrest. Design, Setting and Participants: Prospective clinical biobank study of data from t
Effects of hyperbaric oxygen treatment (HBO) on nerve regeneration in acellular nerve and muscle grafts were investigated in rats. Nerve and muscle grafts were made acellular by freeze-thawing and the obtained grafts were used to bridge a 10-mm gap in the sciatic nerve on the left and right sides, respectively. Rats were treated with HBO (100% oxygen for 90 minutes at 2.5 atmospheres absolute pres
1. The effects of anandamide on K+ currents and membrane potential have been examined in freshly-isolated smooth muscle cells from rat hepatic artery and the results compared with the effects of this arachidonic acid derivative on tension and membrane potential changes in segments of whole artery. 2. In the presence of 0.3 mM L-NOARG and 10 μM indomethacin, anandamide (0.1-100 μM) and endothelium-
