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Popular Abstract in Swedish Syftet med denna avhandling är att skapa en bättre förståelse för vilken betydelse institutioner har för innovationsprocesser inom regionala innovationssystem. Den fokuserar särskilt på hur olika typer av institutioner på skilda geografiska nivåer samspelar; hur institutionell påverkan förändras i samband med att innovationsprocesser utvecklas över tid; samt vilka möjliEconomic geographers have long been intrigued by the role of institutions in innovation processes. It has been argued that differences in institutions are among the factors explaining the uneven innovative capacity across and within countries. The regional innovation system approach highlights the interrelationships of firms, universities, governmental authorities and other organizations, as well

The social differentiation of mobile work is complex. While some people are in a position of control over, and initiate, mobilities, others are captivated by it (Massey 1994). The focus of this WP is transport workers, those who provide mobility: truck drivers, cycle couriers and uber drivers. It is inspired by previous studies of less privileged workers in the power geometry of mobile work: of se

The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in recent decades: treatment decisions remain challenging in clinical practice, without a specific therapeutic target beyond the relief of symptoms as the most important goal. In view of this scenario, the European League Against Rheumatism (EULAR) promoted and supported an international collaborative study (EULAR S

Background: Demographic changes combined with costly technological progress put a financial strain on the healthcare sector in the industrialized world. Hence, there is a constant need to develop new cost-effective treatment procedures in order to optimize the use of available resources. As a response, the concept of a Mobile Geriatric Team (MGT) has emerged not only nationally but also internatio

This thesis concerns the role of sediment-living macrobenthos in the cycling of nitrogen species and nitrogen transformation in eutrophic freshwater sediments. In my thesis I have, employing 15N-isotope techniques in laboratory experiments, shown the importance of infaunal chironomid larvae and oligochaetes on denitrification in eutrophic lake sediments. Investigated benthic organisms not only ex

Availability of safe, edible food is essential. Food shortage has caused many wars and encouraged people to try to preserve food for a longer time, allowing storage and transport, often in some kind of package/container. The USA showed the way in developing the food sector and already prior to the 2nd World War they had self-service stores filled with packed goods. Europe, however, had to wait to

In 131I SPECT, image quality and quantification accuracy are degraded by object scatter as well as scatter and penetration in the collimator. The characterization of energy and spatial distributions of scatter and penetration performed in this study by Monte Carlo simulation will be useful for the development and evaluation of techniques that compensate for such events in 131I imaging. METHODS: Fi

The work presented in this thesis has aimed to investigate and implement techniques for ultrasonic measurements in structural health monitoring applications for civil structures. The focus of the work has been to make these systems practical in real applications, where the large size of the structures, and the changing environments they are exposed to, pose problems for many methods which otherwis

Context. HR 10 has only recently been identified as a binary system. Previously thought to be an A-type shell star, it appears that both components are fast-rotating A-type stars, each presenting a circumstellar envelope. Although showing complex photometric variability, spectroscopic observations of the metallic absorption lines reveal variation explained by the binarity, but not indicative of de

Sediments from the only permanent lake on the island of Jan Mayen (71°N, 08°30′W), Lake Nordlaguna (NL), were investigated. The lake, with an area of ∼1 km2, is situated at the foot of the world's northernmost active subaerial volcano and is separated from the sea by a 150–240 m wide beach barrier, which reaches 4–5 m above sea level. Most of the lake is deeper than 25 m, with the deepest part bei

Objective: To identify and quantify potential risk factors for osteoarthritis (OA) following traumatic knee injury. Design: Systematic review and meta-analyses that estimated the odds of OA for individual risk factors assessed in more than four studies using random-effects models. Remaining risk factors underwent semiquantitative synthesis. The modified GRADE (Grading of Recommendations Assessment

Mental health disorders are usually gendered, with more women being diagnosed with depression for example. This elicits guidelines on how to diagnose mental health according to symptoms common to women, which in turn normalises those practices. This creates legal norms which are reflected when screening for such conditions; however, they require scrutiny, especially as they become formalised in or

Background Multiple myeloma cells uniformly overexpress CD38. We studied daratumumab, a CD38-targeting, human IgG1κ monoclonal antibody, in a phase 1-2 trial involving patients with relapsed myeloma or relapsed myeloma that was refractory to two or more prior lines of therapy. Methods In part 1, the dose-escalation phase, we administered daratumumab at doses of 0.005 to 24 mg per kilogram of body

Context. Observational evidence indicates that the orbits of extrasolar planets are more various than the circular and coplanar ones of the solar system. Planet-planet interactions during migration in the protoplanetary disc have been invoked to explain the formation of these eccentric and inclined orbits. However, our companion paper (Paper I) on the planet-disc interactions of highly inclined an

Background: Residual air accumulated air in the pulmonary veins constitutes a challenge to achievment of complete de-airing in open left heart surgery. To adress this problem, a conceptual method for de-airing was developed in Lund comprising bilateral opening of the pleurae to induce pulmonary collapse and a strategy with gradual pulmonary reperfusion and ventilation at weaning from cardiopulmona

Background: T1D and AITD are autoimmune disorders commonly occurring in the same family and even in the same individual. The genetic contribution to these disorders is complex making uncovering of susceptibility genes very challenging. The general aim of this study was to identify loci and genes contributing to T1D/AITD susceptibility. Our strategy was to perform linkage and association studies in

It has been shown that the exposure to airborne particulate matter is one of the most significant environmental risks people face. Since indoor environment is where people spend the majority of time, in order to protect against this risk, the origin of the particles needs to be understood: do they come from indoor, outdoor sources or both? Further, this question needs to be answered separately for

STUDY QUESTION: Do serum levels of anti-Müllerian hormone (AMH) change in women of reproductive age following dietary and surgery-induced weight loss?SUMMARY ANSWER: AMH levels increased after very low-calorie diet (VLCD) before surgery and decreased at 6 and 12 months after Roux-en-Y gastric bypass (RYGB), beyond expected normal age-related decline.WHAT IS KNOWN ALREADY: Obesity has negative effe

We report and compare highly resolved, simultaneously recorded absorption and CD spectra of active Photosystem II (PSII) samples in the range 440-750 nm. From an appropriately scaled comparison of spinach membrane fragment (BBY) and PSII core spectra, we show that key features of the core spectrum are quantitatively represented in the BBY data. PSII from the cyanobacterium Synechocystis 6803 displ

With today’s rapid changes in socio-economy and technology, knowledge and learning are critical issues for private and civil service organizations. The needs for competence development range from short informal courses (without ECTS credits) to formal courses at university level (with ECTS credits). This article describes objectives and results of a Leonardo project, eGIS+ that developed and imple