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High-frequency ultrasound of skin involvement in systemic sclerosis reflects oedema, extension and severity in early disease.

OBJECTIVE: The aim was to compare skin assessment by palpation and by high-frequency ultrasound in patients with SSc with disease duration <2 yrs. METHODS: Skin thickness and skin echogenicity were measured by 20 MHz ultrasound at five different anatomical sites in 106 individuals within 2 yrs from the first non-Raynaud's symptom and compared with the modified Rodnan skin score (mRss). RESULTS: Th

Great apes can defer exchange: a replication with different results suggesting future oriented behavior.

The topic of cognitive foresight in non-human animals has received considerable attention in the last decade. The main questions concern whether the animals can prepare for upcoming situations which are, to various degrees, contextually or sensorially detached from the situation in which the preparations are made. Studies on great apes have focused on tool-related tasks, e.g., the ability to selec

Another Dam Development Project? Development-forced displacement and resettlement in Nepal

In Nepal, dams have been targeted as the most viable means of energy generation. However, dam projects often necessitate the relocation and resettlement of people to make way for reservoirs; processes that may pose great challenges for affected people, given that their homes, land, and livelihoods are lost to some extent. This thesis analyzes the challenges facing the Nepali state in ensuring that

Norm Formation from the Inside of a Court

ABSTRACT The overarching aim of this sociology of law study is to explore internal processes at a court to get deeper knowledge of norms within this legal organisation. The point of departure is a specific research interest in studying professional norms on ‘good treatment’ in a local court. Another aim is to study the importance that the internal professional norms have on the external treatment

Inductive Analysis of a Multiconductor System Prototype

Broadband circuit models for electric machines are effective means to understand, predict, and control the phenomenon of conducted Electromagnetic Interference (EMI) from immunity/susceptibility perspective. These models should cover the capacitive and inductive coupling behavior of the component along the frequency band of interest. The circuit models when used under generic SPICE simulation soft

Cerebellar pathways and mechanisms in classical conditioning

Popular Abstract in Swedish Hjärnan ansvarar för styrningen av vårt beteende. Exempelvis kan skador på hjärnan vara förödande för vår motorik eller förändra vår personlighet. Hur hjärnan exakt ger upphov till vårt beteende är i huvudsak okänt men hjärnans betydelse för vissa delar av vårt beteende har studerats genom att bryta ner vårt beteende i avgränsade, identifierbara beståndsdelar. Ett avgräIt has been suggested that the cerebellar mossy fibre afferents transmit the conditioned stimulus (CS) information to the cerebellum. Several studies are consistent with this suggestion but alternative explanations have not been excluded. In conditioned ferrets, the forelimb CS was replaced by a direct stimulation of the cerebellar mossy fibre afferents. It was found that true conditioned response

Prayer in Peasant Communities : Ideals and Practices of Prayer in the Late Medieval Ecclesiastical Province of Uppsala, Sweden

The aim of this study has been to identify, explain and delineate praying among peasant communities in the ecclesiastical province of Uppsala, Sweden. Four aspects have been examined through the perspectives of ideals and practices, namely the standards of prayer, devotional prayer, prayer in times of need and prayer cultures. The standards of prayer considered the physical and mental behaviour of

Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men

Aims Tumour necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine, which is implicated in some metabolic disorders and may play a role in the development of cardiovascular disease. We examined whether plasma TNF-alpha is related to established cardiovascular risk indicators, plasma levels of soluble cellular adhesion molecules and carotid artery intima-media thickness determined by ultra

Studies of water vapor transport and sorption in wood

This thesis deals with the evaluation of measurements of water vapor transport and sorption in wood. It mainly concerns measurements of the weight response of a sample after a step change in relative humidity. The thesis consists of an introduction and eight papers. The eight papers have the following contents: 1. A description of the instrumentation and its performance characteristics. 2. Some f

Szabadgyokok es reaktiv nitrogen speciesek szerepe a diabetes kesoi szovodmenyeinek kialakulasaban patkanyban

In this time-course study the levels of different reactive species, especially those of nitric oxide and peroxynitrite were determined in streptozotocin-induced diabetic rat tissues at different time-points after the onset of the disease, before the development of histopathological damages. Significantly higher steady state free radical concentrations were found in the liver 3 weeks after the onse

Förhandlingsparlamentarism: en jämförande studie av riksdagen och folketinget

This thesis is about bargaining in the Swedish Riksdag and the Danish Folketing. It departs from the propositions, forwarded by Swedish and Danish scholars. (1) that the level of conflict in the parliaments have increased and (2) that minority governments are weak and unable to pursue a consequent and responsible economic policy. It examines the function of bargaining between political parties (em

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This study investigates the syntax, semantics and information structure of it-cleft constructions in German and Swedish. The syntactic analysis is presented within a standard framework of generative theory. In defining genuine cleft constructions, both the syntactic and the semantic structures of clefts are taken into consideration. Here, it proves essential to distinguish between different kinds

Biodegradation of phenol at low temperature using two-phase partitioning bioreactors

Two-phase partitioning bioreactors offer many advantages for the removal of toxic pollutants. In particular, such systems can be loaded with very large quantities of pollutants without risks of microbial inhibition, they are self-regulated and they prevent the risks of hazardous pollutant volatilisation during aerobic treatment. However, their potential has never been tested at low temperatures. P

Fabrication and Characterisations of New Ultra-thin Silicon Detectors as Pre-Cell Hit Detectors for a Cell Irradiation Facility at LIBAF

For the development of single–ion irradiation system for living cells at the Lund Ion Beam Analysis facility (LIBAF) newly developed pre-cell (PC) detectors have been investigated. Central to the thesis is the fabrication and initial characterization of more than 100 ultra-thin silicon detectors having different thicknesses down to 5 μm with active areas ranging from 0.71 to 0.172 mm2, to be used

On the role of the retinoblastoma tumor suppressor gene in hematopoietic differentiation

Popular Abstract in Swedish RB-GENEN SKYDDAR OSS MOT CANCER OCH STYR UTMOGNADEN AV BLODCELLER. Frisk och sjuk blodbildning: Varje dag bildas det ungefär ett tusen miljarder blodkroppar av olika sorter i vår benmärg. Varje dag, livet ut. Denna imponerande massproduktion av celler är livsnödvändig. Dom vita blodkropparna ser tex till att vi inte dukar under i infektioner, dom röda transporterar deThe aim of this study was to investigate the role of some tumor suppressor gene products (with emphasis on the retinoblastoma suppressor gene product) in the regulation of differentiation and proliferation in leukemic and normal hematopoietic cells. For this purpose, the expression of the tumor suppressor genes RB, p53 and p16 were artificially altered. Cells used were human leukemic cell lines an

Fabrication of cantilever chip with complementary micro channel system in SU-8 for biochemical detection

This thesis presents the works on fabrication and measurements done with micro cantilevers and a micro channel system, fabricated in the photo-resist SU-8. SU-8 is a polymer patterned by UV lithography which offers a cheap and fast processing and is an interesting alternative to standard Si techniques. For the structures intended here, it proved to be a well suited material and promising results w

Christopher Polhem: Technical innovations and the metaphorical mind

Christopher Polhem (1661-1751), called the father of Swedish mechanics, is the most famous figure in Swedish history of technology and our nation's foremost inventor ever. Remarkably enough, a close survey in a monograph has never been written on this inventor who in many ways initiated the technical and industrial development of Sweden. In this project will Polhem for the first time get a broad a

Christopher Polhem: Tekniska innovationer och det metaforiska tänkandet

Christopher Polhem (1661-1751), called the father of Swedish mechanics, is the most famous figure in Swedish history of technology and our nation's foremost inventor ever. Remarkably enough, a close survey in a monograph has never been written on this inventor who in many ways initiated the technical and industrial development of Sweden. In this project will Polhem for the first time get a broad a

Protein-RNA interplay in translation. Structural studies of RRF, SelB and L1.

Popular Abstract in Swedish Allt levande består till stor del av proteiner. De bygger upp muskler och hår, transporterar syre i blodet och ser till att kemin i kroppen fungerar som den ska. Men hur tillverkas då dessa proteiner? Jo i alla celler finns ribosomer, proteinfabriker. En bakterieribosom är ungefär 0.02 mikrometer stor. Den är sammansatt av proteiner och RNA-kedjor. RNA utgör den funktioTranslation is a central biological process, that is catalysed by a machinery consisting of RNA and protein. In this thesis three different protein components of the bacterial protein synthesis system have been structurally studied. Ribosome recycling factor (RRF) is essential for the recycling step of the translation cycle, elongation factor SelB is a specialised elongation factor needed for co-t