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Problematic gambling has been suggested to be a possible consequence of dopaminergic medications used mainly in neurological conditions, i.e. pramipexole and ropinirole, and possibly by one antipsychotic compound, aripiprazole. Patients with Parkinson's disease, restless legs syndrome and other conditions potentially treated with dopamine agonists, as well as patients treated for psychotic disorde
Pregnancy-related factors are important for short- and long-term health in mothers and offspring. The nationwide population-based Swedish Medical Birth Register (MBR) was established in 1973. The present study describes the content and quality of the MBR, using original MBR data, Swedish-language and international publications based on the MBR. The MBR includes around 98% of all births in Sweden.
Purpose: To provide a focused review of sickle cell retinopathy in the light of recent advances in the pathogenesis, multimodal retinal imaging, management of the condition, and migration trends, which may lead to increased prevalence of the condition in the Western world. Methods: Non-systematic focused literature review. Results: Sickle retinopathy results from aggregation of abnormal hemoglobin
Pancreatic cancer is known for its propensity to metastasize. Recent studies have challenged the commonly held belief that pancreatic cancer is a stepwise process, where tumor cells disseminate late in primary tumor development. Instead it has been suggested that pancreatic tumor cells may disseminate early and develop independently and in parallel to the primary tumor. Circulating tumor cells can
Aims and objectivesThe aim was to explore and describe the child's active participation in daily healthcare practice at children's hospital units in Sweden.Objectives(a) Identify everyday situations in medical and nursing care that illustrate children's active participation in decision‐making, (b) identify various ways of active participation, actual and optimal in situations involving decision‐ma
The minimum edge dominating set (MEDS) is one of the fundamental covering problems in graph theory, which finds many practical applications in diverse domains. In this paper, we propose a meta-heuristic approach based on genetic algorithm and local search to solve the MEDS problem. Therefore, the proposed method is considered as a memetic search algorithm which is called Memetic Algorithm for mini
In this chapter, speech enhancement and echo cancellation for hands-free mobile telephony are discussed. A number of microphone array methods have been tested and results from car measurements are given. Traditional methods such as linearly constrained beamforming and generalized sidelobe cancelers are discussed as well as array gain optimization methods. An in situ calibrated method which gives a
Spectral properties of the weighted Laplace operator in the presence of fractal boundaries are numerically investigated for both Neumann and Dirichlet boundary conditions. This corresponds to the characterization of heat and mass transport in microchannels with irregular and rough surfaces induced by the microfabrication process. The axial velocity field with no-slip boundary conditions, represent
In the past decades, numeracy has taken an increasingly important place in the study of human capital formation, as well as in literacy studies and studies on formal education and book production. In order to understand levels of education, scholars have recently tried to develop new ways to measure the level of education, particularly because it has since become apparent that the measures of lite
Pancreatic cancer has a dismal prognosis and there is an increasing and unmet need to identify better diagnostic and therapeutic targets in order to ameliorate the course of the disease. HMGB1, a nuclear DNA-binding protein that acts as a transcription factor, is currently in the limelight. HMGB1 exhibits a dual role in pancreatic cancer; when intracellular, it acts as an anti-tumor protein stabil
The structure tensor is a powerful tool describing the local intensity structure of an image or image sequence. In this paper we give a model for the noise distribution of the components of the tensor. In order to do so we have also investigated some properties of the gamma distribution. We show that, given an input image corrupted with Gaussian noise, the noise in the structure tensor can be modThe structure tensor is a powerful tool describing the local intensity structure of an image or image sequence. In this paper we give a model for the noise distribution of the components of the tensor. In order to do so we have also investigated some properties of the gamma distribution. We show that, given an input image corrupted with Gaussian noise, the noise in the structure tensor can be mode
All languages borrow words from other languages. Some languages are more prone to borrowing, while others borrow less, and different domains of the vocabulary are unequally susceptible to borrowing. Languages typically borrow words when a new concept is introduced, but languages may also borrow a new word for an already existing concept. Linguists describe two causalities for borrowing: need, i.e.
The sFLASH project at DESY is an experiment to study direct seeding using a source based on the high-harmonic generation (HHG) process. In contrast to SASE, a seeded FEL exhibits greatly improved longitudinal coherence and higher shot-to-shot stability (both spectral and energetic). In addition, the output of the seeded FEL is intrinsically synchronized to the HHG drive laser, thus enabling pump-p
Malignant melanoma is one of the most aggressive tumors which often gives metastasis to distant organs thereby limiting the chances of survival. Brain metastasis occurs in nearly half of the advanced tumors. In order to improve outcome early diagnosis is important. The discovery and better understanding of genetic and epigenetic changes is essential for developing new effective therapies, which ca
Medical students’ access to clinical supervision when rotating through hospital workplaces and the quality of that supervision are and have been an area of growing professional and societal concern. Increased training measures targeted at supervising physicians have been suggested to address this issue. Traditionally, such training has focused on offering physicians opportunities to develop as sup
Several studies demonstrate the value of residents’ voices in the place branding process, however, relatively little is known about how residents experience participating in place branding campaigns and the consequences for place identity. This chapter explores the question of whether participatory branding initiatives could potentially lead to more inclusionary representational spaces in the city
Dispersal is important for determining both species ecological processes, such as population viability, and its evolutionary processes, like gene flow and local adaptation. Yet obtaining accurate estimates in the wild through direct observation can be challenging or even impossible, particularly over large spatial and temporal scales. Genotyping many individuals from wild populations can provide d
