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This study was undertaken to evaluate the role of internalization in the action of the peptide autacoid bradykinin (BK). At 4°C [3H]BK binds to an apparently single class of B2 kinin receptors on DDT1 MF-2 smooth muscle cells (C. M. Munoz, S. Cotecchia, and L. M. F. Leeb-Lundberg, manuscript submitted). At this temperature the [3H]BK binding was confined exclusively to the cell surface. On the oth

Climate change has caused significant impacts on water resource redistribution around the world and posed a great threat in the last several decades due to intensive human activities. The impacts of human water use and management on regional water resources remain unclear as they are intertwined with the impacts of climate change. In this study, we disentangled the impact of climate-induced human

Diamonds are one of the most valuable elements on earth, having the potential to contribute to economic development. However, in recent years, it has come to the world’s attention that the illicit trading in diamonds has financed gruesome wars and human rights abuse, and the problem has not gone away. These diamonds have come to be termed as conflict diamonds. In order to mitigate conflict diamond

We have implemented an Intelligent Tutoring System (ITS) prototype for teaching multi-column addition and subtraction to children aged 5-10, using a digitalized version of the Montessori bank game exercises. An Intelligent Tutoring System is a piece of software that teaches a certain subject to its users, and that typically uses artificial intelligence related algorithms to personalize the educati

This thesis has been performed at Saab Technologies in Gothenburg. Saab is a global defense- and security company that specializes in air-, land and marine defense. Saab in Gothenburg develops effective solutions for monitoring, warning, location and defense systems. The thesis work which has been initiated by Saab, involves development of methods and tools in order to dimension the network compon

Kan geofysiska undersökningsmetoder vid undersökning av förorenade områden bidra till att uppnå en giftfri miljö? Sverige lider idag av stora mängder giftiga ämnen i marken som dumpats av olika sorters industrier under åtskilliga år, från en tid då ekonomiskt välstånd stod högt på agendan och okunskapen om miljön var utbredd. De här föroreningarna riskerar nu att skada både människors hälsa och mA central part of the risk assessment of contaminated sites is to conduct surveys of the area to assess the need for remediation. Through literature and interview studies this essay examined how geophysical methods can help to improve the environmental risk assessment of contaminated sites in Sweden. The results point to five main strengths in combining geophysical methods with the conventional me

"Growing up in Rosengård is quite nice!" – Social capital - a different perspective to consider young adults in Rosengård [translated title]. The aim of this study was to understand young adults’ experiences of living in the segregated and stigmatized inner-city neighbourhood of Rosengård. This area is well known in Sweden as a poverty zone, with high criminality, drugs and unemployment

Kol har lagrats is torvmarker i tusentals år och idag innehåller torvmarkerna ca en tredjedel av all markkol på jorden. Det råder stor osäkerhet hur torvmarker kommer att reagera på klimatförändringar. Detta beror på att de kalla, blöta och syrefattiga förhållandena leder till motsatta effekter för global uppvärmning; dels lagras koldioxid eftersom fotosyntesen är större än respirationen (kylande Northern peatlands have accumulated carbon for thousands of years and currently hold around one third of all soil carbon on earth. Large uncertainties are associated with predictions of how northern peatlands will react to climate change. This is because the cold, wet and anaerobic conditions lead to two opposing forces from a radiative forcing perspective – CO2 sequestration from photosynthesis b

Skiljeförfarandet är en privat alternativ tvistlösningsmetod, med syfte att snabbt och slutligt avgöra tvister utan insyn utifrån. Från den utgångspunkten är det viktigt att skiljeförfarandet inte följs av en långdragen och offentlig domstolsprocess. Skiljedomar kan därmed inte överprövas på materiella grunder. För att skiljeförfarandet ska vara ett rättssäkert och godtagbart alternativ till domstThe arbitration procedure is a private alternative dispute resolution method aimed at quickly and definitively resolving disputes without external oversight. From this perspective, it is important that the arbitration is not followed by a prolonged and public court process. Arbitral awards, therefore, cannot be appealed on substantive grounds. However, for the arbitration to be a legally secure an

Electrification of the automotive industry calls for high performing electric engines. Since the use of iron from primary sources in the production of engine cores has a high environmental impact, it would be beneficial if they could be made mostly from recycled materials. Soft magnetic composites used as cores in electric engines have lower mechanical strength compared to the alternatives. This i

Sports have been shown to influence and shape humans in many ways. However, how sports background influences decision-making in early stage entrepreneurial ventures has not been examined closely. Hence, this thesis addressed this gap and explored how sports backgrounds influence decision-making in early-stage ventures. More specifically, it delved into how experience as an elite team sports athlet

Uppsatsen syftar till att synliggöra och problematisera hur omfattningen av domens negativa rättskraft förhåller sig till konsumentens rättigheter härrö-rande ur EU-rätten. Efter en jämförelse mellan HD:s rättspraxis och EU-domstolens avgöranden i konsumenträttsliga mål är min slutsats att den rätts-kraftslära HD utvecklat kan försämra konsumenträttens genomslag och såle-des strida mot den EU-rättThis essay aims to illustrate and problematize how the extent of res judicata rules relates to EU-regulated consumer rights. After a comparison between case law from the Swedish High Court (HD) and the European Court of Jus-tice (ECJ), I’ve concluded that the HD-created jurisprudence regarding res judicata might be incompatible with the EU principle of effectiveness. This is due to its potential i

Inom läkemedelsindustrin är det väldigt viktigt att göra en noggrann kontroll av läkemedel så att de är tillräckligt rena för personen som ska använda dem. En vanlig analysteknik i industrin är HPLC (High Performance Liquid Chromatography), som används för att separera och identifiera olika ämnen i exempelvis krämer eller tabletter. Analysmetoden används för att upptäcka orenheter i produkterna. HPLC is one of the most widely used analytical techniques in the pharmaceutical industry used for separation and identification of compounds in complex formulations. Despite its advantages, HPLC method development remains challenging. This is due to the need to optimize multiple interdependent parameters simultaneously, while gaining high precision, reproducibility, and efficiency. Even minor cha

This thesis explores the state-of-the-art methods for the optimization of Wireless Power Transfer (WPT) for Radio Frequency (RF) energy harvesting with a view of increasing the efficiency of the Radio Frequency to Direct Current (RF-to-DC) conversion, which is a key parameter in the creation of Zero Energy Devices (ZEDs) in the context of Internet of Things (IoT). The research focuses on waveform

As supply uncertainties and increased lead times were more prominent than ever during the covid-19 pandemic, many companies experienced disrupted supply chains and realized the weaknesses in their inventory management and supply chain planning. Many organizations, including the case company in this thesis, Beijer Ref, experienced the impact of the bullwhip effect on their operations. The bullwhip

The increase in crime is a high-profile problem area within the criminal policy debate in Sweden. Most political parties present stricter penalties as a possible solution. It is regulated by Swedish law how inmates shall, during their imprisonment, receive support in order to successfully reintegrate into society upon their release. This is in order to not relapse into crime. At the same time, for

Isolation of mycobacteriophages for tuberculosis treatment Tuberculosis (TB) is the second deadliest infectious disease after Covid-19. Due to the recent rise in antibiotic resistance, new avenues for TB treatment need to be explored. Bacteriophages are viruses that can infect bacteria and kill them. Mycobacteriophages consist of a phage head containing dsDNA and tail fibres that are used to atta

The creation of floral resources for pollinators, such as flower strips, is seen as a relevant and needed intervention but comes with both cost and an opportunity for farmers. It may be worth it if, for example, pollinators are attracted to pollinator-dependent crops and deliver crop pollination. Unfortunately, since pollinators are mobile organisms, the spatial distribution of crop pollination re