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Studies were conducted to elucidate co-receptor spectrum and function of the inflammatory receptor, CMKLR1/ChemR23, which was recently identified as the receptor for the cystatin-like chemoattractant, TIG2, also named chemerin. An infection model was applied based on stably transfiected NP-2.CD4 host cells expressing various co-receptor constructs and exposed to panels of HIV-1, HIV-2 and SIV prim

In-situ nutrient sensors are now a proven technology. Having ion membranes eliminates the need for ultrafiltration, and consequently the sensors can be located at suitable places in any of the reactors. This gives the potential for new control structures for the control of nitrification, denitrification, and phosphorus removal. In the paper some examples of such controllers are demonstrated as use

This paper presents a study of phase noise in CMOS Colpitts and LC-tank oscillators. Closed-form symbolic formulas for the 1/f/sup 2/ phase-noise region are derived for both the Colpitts oscillator (either single-ended or differential) and the LC-tank oscillator, yielding highly accurate results under very general assumptions. A comparison between the differential Colpitts and the LC-tank oscillat

Neutrophil apoptosis occurs both in the bloodstream and in the tissue and is considered essential for the resolution of an inflammatory process. Here, we show that p38–mitogen-activated protein kinase (MAPK) associates to caspase-8 and caspase-3 during neutrophil apoptosis and that p38-MAPK activity, previously shown to be a survival signal in these primary cells, correlates with the levels of cas

In order to clarify the origins and pathways of vasoactive intestinal polypeptide (VIP)-containing nerve fibers in cerebral blood vessels of rat, denervation experiments and retrograde axonal tracing methods (true blue) were used. Numerous VIP-positive nerve cells were recognized in the sphenopalatine ganglion and in a mini-ganglion (internal carotid mini-ganglion) located on the internal carotid

Popular Abstract in Swedish Svensk sammanfattning (Swedish Summary) Inflammatoriska sjukdomar i luftvägarna tillhör ett av de vanligaste skälen till ohälsa. Astma, både allergisk och icke allergisk, kan debutera redan under de första levnadsåren och kan på lång sikt ge kroniskt nedsatt lungfunktion. Bland medelålder's och äldre personer är kronisk obstruktiv lungsjukdom (KOL) vanligast, oftast etEndothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. The present thesis concerns the role of th

Popular Abstract in Swedish Teknikutvecklingen leder till att vi får allt mer avancerade elektroniska medicinska implantat. Dessa spänner idag från den välkända hjärtpacemakern till avancerade hörselimplantat, hjärnstimulatorer och implanterbara medicinpumpar. Med de allt mer avancerade implantaten har också deras behov av att ta emot styrsignaler från utsidan av kroppen, och deras förmåga att sänWith the increased sophistication of medical implants, there is a growing need for flexible high-speed communication with the implant from outside the body. Today the communication is done by an inductive link between the implant and an external coil at a low carrier frequency. Extended range and communication speed are possible to achieve by increasing the carrier frequency and the bandwidth. One

The effects on wood of simultaneous mechanical and moisture loading are studied. In order to clarify the mechano-sorptive behaviour of wood, a review of different phenomena presented in the literature is included. Compressive tests have been performed on spruce. The tests have been performed with both constant load and varying load. The humidity has been varied during the tests. The properties of

To mimic the electron donor side of Photosystem II (PSII), a number of supramolecular model complexes have been designed and synthesized. Ruthenium(II) tris-bipyridyl complexes have been used in most cases as photosensitizers, mimicking the function of P-680 in PSII. As electron donors, monomeric and dimeric manganese complexes and tyrosine have been introduced into the supramolecular systems, mod

The principal fate during litter decomposition and mineralization is rather well established only for a limited number of elements, mainly essential plant nutrients and a few potentially very toxic metals. Elements which occupy the majority of the positions in the periodical system seems almost unknown in this context. The objectives were, therefore to assess differences in the behavior of 58 mine

Pyridinium triflate protic ionic liquids have been demonstrated to be highly dissociated, and nonstoichiometric compositions have been used in protic energy devices such as the all-organic proton battery. Herein, we use a combination of pulsed field gradient NMR spectroscopy and electrochemical impedance spectroscopy to investigate the charge transport properties of the nonstoichiometric protic io

Originally believed to primarily affect neurons, Parkinson's disease (PD) has recently been recognized to also affect the functions and integrity of microglia and astroglia, two cell categories of fundamental importance to brain tissue homeostasis, defense, and repair. Both a loss of glial supportive-defensive functions and a toxic gain of glial functions are implicated in the neurodegenerative pr

The objective of this paper is to present the main results of an engineering-research project dealing with model-based evaluation of waste streams treatment from a biotech company. This has been extensively done in domestic treatment systems, but is equally important, and with different challenges in industrial wastewater treatment. A new set of biological (activated sludge, anaerobic digestion),

IntroductionSelf efficacy (SE) relates to pupils' beliefs about their own capacities within a given field. It has been shown that an overestimation of one's own SE beliefs affects learning outcomes negatively. In the present study we examine SE beliefs in writing skills in two groups of secondary school pupils, one with hearing impairment, the other without.PurposeText writing is a complex skill,

This paper aims to describe the reasons why abnormal heat transfer occurs under the condition of regenerative cooling applied in scramjet engines. Supercritical n-decane flowing in a horizontal tube under various mass flow rates (G = 0.001, 0.002, 0.003, 0.004 kg/s) and heat fluxes (qw = 100, 200, 300, 400 kW/m2) is investigated by numerical simulations. The mechanisms of the abnormal heat transfe

Non-invasive characterization of brain structure has been made possible by the introduction of magnetic resonance imaging (MRI). Graph modeling of structural connectivity has been useful, but is often limited to defining nodes as regions from a brain atlas. Here, we propose two methods for encoding structural connectivity in a huge brain graph at the voxel-level resolution (i.e., 850'000 voxels) b

When a literary text is translated from a dominated to a dominating language, Yvonne Lindqvist (2018) observes, it generally undergoes a cosmopolitanizing process. Consecrated by the dominating literary culture, the text is lifted up to a transnational level and deemed significant for an international readership. Lindqvist’s observation is confirmed by the English translations of Swedish working-c

Objective: The introduction of hematopoietic stem cell transplantation (HSCT) has significantly improved the life-span of Hurler patients (mucopolysaccharidosis type I-H, MPS I-H). Yet, the musculoskeletal manifestations seem largely unresponsive to HSCT. In order to facilitate evidence based management, the aim of the current study was to give a systematic overview of the orthopaedic complication