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In the in vitro motility assay, actin filaments are propelled by surface-adsorbed myosin motors, or rather, myosin motor fragments such as heavy meromyosin (HMM). Recently, efforts have been made to develop actomyosin powered nanodevices on the basis of this assay but such developments are hampered by limited understanding of the HMM adsorption geometry. Therefore, we here investigate the HMM adso
Personuppgifter blir allt viktigare i den digitala ekonomin. Omfattningen av insamling och behandling ökar och riskerar att hota den personliga integriteten. Trots att personlig integritet och respekten för privatlivet räknas som som en mänsklig rättighet har dessa en väldigt svag position relativt andra rättigheter och samhälleliga behov. Detta ter sig ganska underligt eftersom den personliga intPersonal data is becoming increasingly important in the digital economy. The scope of collection and treatment increases and may threaten personal integrity. Although privacy is regarded as human right, privacy has a very weak position relative other rights and social needs. This is quite strange as privacy is often considered a prerequisite for many of the traditional rights such as freedom of sp
Reflections of Fire. Images of the First World War in Sweden This thesis investigates the cultural impact of the First World War in Sweden, and how it shaped Swedish images and narratives about war and neutrality from 1914 to 1935. In line with Paul Fussell, George L. Mosse, and Jay Winter, among others, I discuss the symbolic, discursive aspects of the war at a popular, everyday level. The theor
Popular Abstract in English Extraction of valuable substances from plants using a solvent has been practised in many fields. One of the examples is making coffee or tea using hot water. In agricultural and food industry, there are tons of wastes containing valuable compounds that can be extracted before they go to incineration. Extractions are usually performed in organic solvents such as methanolPressurised hot water is an environmentally friendly alternative to hazardous organic solvents such as methanol and heptane. One of the many applications of using pressurised hot water extraction (PHWE) is to extract polyphenols from plants. The challenges in PHWE lies with the optimisation of extraction yield. One factor that is often overlooked is the risk of degradation of thermally labile comp
Popular science summary: Huntington’s disease (HD) is a rare disease but more commonly found in ethnic populations belonging to Europe and North America than in those of Asian or African ancestry. This disease causes loss of neurons in different areas of the brain, that gives rise to different behavioural changes and psychological disturbances including involuntary movements and depression. The
Abstract Dopamine as a neurotransmitter was discovered in the late 1950s. The dopaminergic system is one of the most well studied neurotransmitter systems in the brain. It is involved in many important functions, such as motor function control; reward, reinforcement, motivation, associative learning, salience information encoding; cognition etc. Disturbances of the dopaminergic system may result
Background: The global gene regulator Special AT-rich sequence-binding protein1 (SATB1) has been reported to reprogramme tumour cells into a more malignant phenotype and associate with poor clinical outcome in several cancer forms. In this study, we investigated the molecular correlates and prognostic impact of SATB1 expression in human epithelial ovarian cancer (EOC). Findings: Immunohistochemica
To go with HEXTRA worklist: HIV-1 Single Genome Amplification Worksheets Sequencing plate set-up Date Prepared: 31/07/18 Plate ID: S0039 Operator: Sara/Jamirah * Shaded wells with weak bands (red [extremely weak], orange [moderately weak] and yellow [weak] bands). Date collected: Collected by: Signature: Page 1 of 1 image1.emf E18_07 1 2 3 4 5 6 7 8 9 10 11 12 A 271117_A02 050318_E10 050318_F10 03
https://www.virology.lu.se/sites/virology.lu.se/files/s039_310718.docx - 2026-06-27
Partially premixed combustion (PPC) in internal combustion engine as a low temperature combustion strategy has shown great potential to achieve high thermodynamic efficiency. Methanol due to its unique properties is considered as a preferable PPC engine fuel. The injection timing to achieve methanol PPC conditions should be set very close to TDC, allowing to utilize spray-bowl interaction to furth
Intracerebral transplantation of porcine embryonic dopamine-producing neurons has been suggested as a method to treat patients with Parkinson's disease. Even though the brain is an immunologically privileged site, neuronal xenografts are usually rejected within a few weeks. T cells are important for this process, but the exact cellular events leading to rejection are poorly characterized. Brain ce
We present a study of high-order-harmonic generation (HHG) assisted by extreme ultraviolet (XUV) attosecond pulses, which can lead to the excitation of inner-shell electrons and the generation of a second HHG plateau. With the treatment of a one-dimensional model of krypton, based on time-dependent configuration interaction singles (TDCIS) of an effective two-electron system, we show that the XUV-
OBJECTIVE:: Arterial stiffening increases with age and is associated with increased cardiovascular risk. Several risk factors have been shown to predict the development of arterial stiffening; however, a positive family history (FH+) of cardiometabolic disease (CMD) and hypertension has not been extensively studied. We hypothesize that FH+ of CMD plays a significant role in the development of arte
In this letter, the fading statistics of wireless channels in high-speed railway cutting scenarios are characterized based on measurements. A multiple scattering model called second-order scattering fading (SOSF) is used to model the small-scale fading considering the influence of cuttings and bridges. The SOSF model can offer the possibility of analytical estimation for different fading severitie
Background: Incidental gallbladder cancer (IGBC) is an unexpected finding when a cholecystectomy is performed upon a benign indication, and the use of routine or selective histological analysis of gallbladder specimen is still debated. The aim of this study was to investigate whether the proportion of submitted gallbladder specimens for pathological investigation influences the proportion of IGBC
In order to improve the surface quality of TC4 titanium alloy parts, the effect of grinding parameters on surface integrity must be known. In this research, an experimental analysis has been conducted to understand the effect of grinding parameters, including cutting velocity, feed rate, grinding depth and abrasive size, on material removal and surface integrity. Before conducting experiment, test
AIMS : Transcatheter aortic valve implantation (TAVI), now a common procedure to treat high-risk patients with severe aortic stenosis, has rapidly been expanding into younger and lower-risk populations, creating a need to better understand long-term outcome after TAVI. The aim of the present investigation was to determine the incidence, risk factors for, clinical presentation of, and outcome after
BACKGROUND: Current clinical assessments of motor function in Huntington's Disease (HD) rely on subjective ratings such as the Unified Huntington's Disease Rating scale (UHDRS). The ability to track disease progression using simple, objective, inexpensive, and robust measures would be beneficial.METHODS: One objective measure of motor performance is hand-tapping. Over the last 14 years we have rou
