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Dementia is a decline in cognitive function that impairs a person’s previous level of social and occupational function. Dementia is a very common medical condition that can result from diverse causes. Dementias are classified based on common clinical, genetic, and neuropathological features. The most common cause of dementia is Alzheimer’s disease. Other major classes of disorders that cause demen

The possible importance of virus infections before the development of islet autoimmunity and then for the appearance of clinical type 1 diabetes is reviewed. There is a lack of specific data on the role of virus to induce islet autoimmunity. There is also a paucity of data to demonstrate that virus infections may contribute to an accelerated disease process resulting in clinical onset of type 1 di

The foundation of this study is a dynamic model, describing wealth effects on aggregate consumption in Sweden based on annual data 1980-2008. The dynamic model is conducted with reference to the life-cycle hypothesis, and results in a short-term as well as a long-term relationship between the examined variables. In general, its method is a conventional cointegration study, where the long term rela

We study a stochastic model of consensus formation, introduced in 2015 by Grinfeld, Volkov and Wade, who called it a multidimensional randomized Keynesian beauty contest. The model was generalized by Kennerberg and Volkov, who called their generalization the Jante's law process. We consider a version of the model where the space of possible opinions is a convex body B in Rd. N individuals in a pop

Characterization of emissions from fires in a laboratory-controlled environment are presented in this report. The project is initiated by the CERN HSE Unit and is called FIRIA, Fire-Induced Radiological Integrated Assessment. The objective of FIRIA is to enhance the knowledge of aerosols emitted from fires in order to develop dispersion models of radiologically-activated material in case of fire.

L-DOPA-induced dyskinesia (LID) is the most common form of hyperkinetic movement disorder resulting from altered information processing in the cortico-basal ganglia network. We here review recent advances clarifying the altered interplay between striatal output pathways in this movement disorder. We also review studies revealing structural and synaptic changes to the striatal microcircuitry and al

The problems of de-blurring, de-noising, compression and segmentation are fundamental problems in image processing. Each of these problems can be formulated as a problem to find some approximation of an initial image. To find this approximation one needs to specify the approximation space and in what space the error between the image and its approximation should be calculated.Using the space of Bo

The selection of pharmaceutical polymorphisms in the final production step is very important in terms of product recovery, properties, and storage. The amorphous, dihydrated crystalline, and anhydrous crystalline forms of paclitaxel were prepared using precipitation, spray drying, and colloid formation methods. These methods were found to be highly efficient and convenient, giving high recovery, s

Many people and organizations across the globe work towards a sustainable future. Artificial intelligence (AI) can be a powerful tool in their efforts.AI technologies, which aim to imitate the natural intelligence of humans and animals, have made enormous progress in the past decade. AI has brought us a whole range of futuristic tools — from self-driving cars to virtual assistants, smart home appl

The phenomena of landgrabbing and monopolizing of water sources have gained increasing attention in recent years. Nevertheless, very few studies have dealt with the problem of the grabbing and concentration of resources from an ethnographic perspective that would make it possible to illustrate the different ways in which dispossession takes place, as well as its concrete mechanisms and effects in

The gas in scattering media absorption spectroscopy (GASMAS) technique was used to investigate the possible presence of free gas pores in human condyle bones, extracted from the tibia in knee revision surgical procedures in response to arthrosis development. Following earlier studies showing free gas presence in femoral head bones, decaying because of inadequate blood flow, we investigated condyle

During recent years, several spectacular collapses happened in large timber structures and the question is what can be done to prevent future failures. The main hypothesis for this project has been that quality assurance, control systems and improved training may be necessary, since the unwanted events are primarily related to human errors. A survey of failures in 127 timber structures has been ma

Absolute quantification of cerebral blood flow, cerebral blood volume and mean transit time is desirable in the determination of tissue viability thresholds and tissue at risk in acute ischaemic stroke, as well as in cases where a global reduction in cerebral blood flow is expected, for example, in patients with dementia or depressive disorders. Absolute values are also useful when comparing seque

This paper explores the concept of organizations as complex human activity systems, through the perspectives of alternative systemic models. The impact of alternative models on perception of individual and organizational emergence is highlighted. Using information systems development as an example of management activity, individual and collective sense-making and learning processes are discussed.

Accumulation of acetate tends to reduce growth and recombinant protein production in E. coli cultivations. Formation of acetate can be avoided by a proper substrate feeding strategy, but most strategies require considerable process knowledge to work well. A feedback strategy is presented that requires minimal a priori information. The key idea is to exploit a characteristic change in the cell meta

What can artificial intelligence learn from the cognitive sciences? We review some fundamental aspects of how human cognition works and relate it to different brain structures and their function. A central theme is that cognition is very different from how it is envisioned in classical artificial intelligence which offers a novel path toward intelligent systems that in many ways is both simpler an

Sweden has during the past decades experienced increasing challenges in suburban, segregated areas: the inhabitants have different cultural and socio-economic backgrounds but despite that, face similar problems. Many inhabitants lack relevant networks as well as other opportunities to become a part of the society. These inhabitants claim they don´t have the “keys” to understand their society and iSweden has during the past decades experienced increasing challenges in suburban, segregated areas: the inhabitants have different cultural and socio-economic backgrounds but despite that, face similar problems. Many inhabitants lack relevant networks as well as other opportunities to become a part of the society. These inhabitants claim they don´t have the “keys” to understand their society and i