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Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) occurs as either a 27- or 38-amino acid neuropeptide and belongs to the vasoactive intestinal polypeptide/glucagon/secretin family of peptides. PACAP and vasoactive intestinal polypeptide have a 68% homology of their amino acid sequences and share three B-type G-protein coupled receptors: VPAC1, VPAC2 and PAC1 receptors. Method

What Christian worship is all about has been discussed and expressed in many contexts: in dogmatic pronouncements, in ecumenical documents and declarations, in the writings of individual theologians. This article is a simple attempt to summarize the essence of some of the more influential of those writings. In order to make it as basic and as uncontroversial as possible I have based it on Bible pa

We present estimates of standardized selection (directional and quadratic) differentials via reproductive success on eight morphological traits in a newly founded long-term study population of great reed warblers Acrocephalus arundinaceus in Sweden. In order to predict the evolutionary response to selection in these traits we present estimates of heritabilities (h(2)), phenotypic (r(P)) and geneti

The fractional dispersion model for natural rivers, extended by including a first order reaction term, contains four parameters. In order to estimate these parameters a fractional Laplace transform-based method is developed in this paper. Based on 76 dye test data measured in natural streams, the new parameter estimation method shows that the fractional dispersion operator parameter F is the contr

In order to obtain biomarker values that reflect body burden of persistent organohalogen pollutants (POP), concentrations of lipophilic POP in serum or plasma are generally expressed on a lipid weight basis, and not on a fresh weight basis. There are two different approaches to determine the lipid content in serum and plasma. The gravimetric determination is more expensive, and longer experience i

Within the paradigm of population dynamics a central task is to identify environmental factors affecting population change and to estimate the strength of these effects. We here investigate the impact of observation errors in measurements of population densities on estimates of environmental effects. Adding observation errors may change the autocorrelation of a population time series with potentia

Malignant hyperthermia susceptibility is diagnosed using an in vitro contracture test (IVCT). In families in which the mutation is known, genetic tests are also available. The inheritance pattern is regarded as autosomal dominant, which predicts equal proportions of men and women affected. The aim of this study was to investigate whether there were sex differences in the diagnostic outcome of the

We propose a rational fabrication method for nanoimprinting moulds by scanning probe lithography. By wet chemical etching, different kinds of moulds are realized on Si( 110) and Si( 100) surfaces according to the Si crystalline orientation. The structures have line widths of about 200 nm with a high aspect ratio. By reactive ion etching, moulds with patterns free from the limitation of Si crystall

In this study, we developed a microdispenser technique in order to create protein patterns for guidance of neurites from cultured adult mouse dorsal root ganglia (DRG). The microdispenser is a micromachined silicon device that ejects 100 picolitre droplets and has the ability to position the droplets with a precision of 6-8 mu m. Laminin and bovine serum albumin (BSA) was used to create adhesive a

This paper presents some functional differences as well as similarities observed when comparing the newly discovered cellobiose dehydrogenase (CDH) from Trametes Villosa (T.v) with the well-characterized one from Phanerochaete chrysosporium (P.c.). The enzymes were physically adsorbed on spectrographic graphite electrodes placed in an amperometric flow through cell connected to a flow system. In t

Purpose: Rollators are used in order to make mobility possible for people with restricted walking ability. The use of rollators is increasing, but little is known about outcomes. The aim of this study was to investigate users' satisfaction with rollators. Method: A follow-up study was carried out in seven Danish municipalities. One month after they got their device, 89 users of rollators were inte

By the use of wavelength-modulation diode laser spectroscopy, water vapor and oxygen are detected in scattering media nonintrusively, at 980 nm and 760 nm, respectively. The technique demonstrated is based on the fact that free gases have extremely sharp absorption structures in comparison with the broad features of bulk material. Water vapor and oxygen measurements have been performed during the

In order to distinguish various film-worlds among themselves and from our intersubjective, shared reality I propose to introduce two parameters: warpedness and enfoldednes. The various ratios between these two parameters serve to create what I call »the film-world map«. The time-imageʼs embeddedness within the temporal dimension is what I mean by strong enfoldedness. A world that is enfolded is a

The need for a scientific formalism for product realization is the translation of a need onto a product which is developed right in time, at the right costs, and fulfills the specifications set out for the product. To achieve this, most existing methods focus on the customer, or on a key technology as the backbone of product development. In this paper, we claim that efforts must be directed toward

This book argues that we are currently witnessing not merely a decline in the quality of social science research, but the proliferation of meaningless research, of no value to society, and modest value to its authors - apart from securing employment and promotion. The explosion of published outputs, at least in social science, creates a noisy, cluttered environment which makes meaningful research

In this study, a new strategy for fault detection and isolation is presented. This strategy is based on the design of a Lüneburg observer which is implemented via pole placement using linear matrix inequalities. Two residuals are formulated based on the state estimation error in order to be utilized in detecting and isolating faults happened on the system. Fault detection problem solves by change

In order to understand how visions and narratives about the Internet are articulated, negotiated, and circulated in China, one needs to address and unpack a number of interrelated issues. It is important to map who has the possibility to articulate visions on the Internet in China, who is actually doing it and why, what having a ‘vision’ actually means, and which platforms different individuals an

Even though anthropogenic nano-sized tungsten carbide nanoparticles (WC NPs) have been found in the environment, there are currently no investigations on their environmental fate. This work studies the interaction between natural organic matter (NOM) and WC NPs, as well as the potential uptake by the aquatic model organism Daphnia magna. We here show that the affinity between WC NPs and humic acid