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Popular Abstract in Swedish Patienter som drabbats av Parkinsons sjukdom (PD) saknar förmågan att medvetet kontrollera sina rörelser. Livslång medicinering krävs, vilket lindrar symptomen och leder till att rörelsemönstret förbättras, men med varierad effektivitet. Trots att de läkemedel (t ex L-DOPA) som finns tillgängliga idag har fantastisk effekt, minskar deras effektivitet i takt med att sjukParkinson’s disease (PD) is a neurodegenerative disorder characterised by motor deficits such as slowness in movement, difficulty in initiating movement and tremor at rest. The cause of these motor symptoms is the selective loss of mesencephalic dopaminergic (mesDA) neurons, located in the substantia nigra (SN). These neurons project axons to the striatum where they release dopamine, a neurotransm

Popular Abstract in Swedish Leukemi kännetecknas av en okontrollerad tillväxt av omogna vita blodkroppar och orsakas av förvärvade genetiska förändringar. Genetiska förändringar eller avvikelser, som är drivande i cancerutvecklingen, uppstår när normala celler delar sig. Identifiering av sådana förändringar på gen-och kromosomnivå är av stor klinisk betydelse. Behandling styrs av vilka genetiska aAcute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children <4 years and adults >50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. In contrast to pediatric ALL, which has a favorable prognosis, adult ALL is associated with a much poorer outcome with less than 40% overall

This essay concerns the legislation and legal procedures concerning the crime “rape”. We focus on rapes committed by young offenders and where young victims (girls) are involved. Media often presents a picture that raped girls don’t get a fair trial because she comes out as a bad looking girl in court. Our purpose has been to investigate and analyse rape from a historical and legal perspective and

Uppsatsen redogör för rättsläget kring uppsägningar och avsked med arbetstagarens brottslighet som grund. För avskedande krävs att arbetstagaren grovt åsidosatt sina åligganden enligt anställningsavtalet och för uppsägning finns ett krav på saklig grund. Vid bedömningen av huruvida saklig grund föreligger ställs krav på hur arbetsgivaren handlat. Arbetsgivaren har en rad lojalitetsplikter gentemotThis essay describes the legal situation regarding ordinary dismissals and summary dismissals based on an employee’s criminal activity. In order for the employer to be able to accomplish a summary dismissal the employee must have severely neglected his obligations against the employer. To accomplish an ordinary dismissal, the employer must show that the dismissal is based on objective grounds. The

Mervärdesskatt och Transfer Pricing är två av de stora områdena inom internationell skatterätt, då det förra är en indirekt skatt och baseras på det subjektiva priset och det senare området tillhör direkt beskattning och använder ett objektivt, fiktivt pris för beräkning kan de vid första anblick sakna anknytning. Det finns dock en risk att justeringar av det pris som använts för Transfer Pricing-Value added tax and Transfer Pricing are two of the major areas of international tax law, as the former one uses a subjective price for the calculation of taxation and the latter one uses an objective price the two regimes seemingly lack interaction. There is however a possibility that an adjustment of the price used for Transfer Pricing purposes might have an effect on the VAT due. VAT is a har

Unlike commonly used regular transformers, high voltage, high frequency, pulsed transformers are generally represented in special purpose applications. This often means that these electrical devices must be tailored in accordance with the specic requirements of the project. The pulse transformer under analysis in this thesis is a prototype machine variation of which will serve as an essential part

Avfallsförebyggande syftar till att förhindra uppkomsten av avfall och är det högst uppsatta målet inom svensk och europeisk avfallshantering. Trots det har avfallsmängderna fortsatt att öka och de prognoser som gjorts inför framtiden visar att mängderna kommer fortsätta att öka med befintliga styrmedel. Syftet med examensarbetet är att undersöka om avfallsförebyggande åtgärder kan anpassa till dWaste prevention aims at preventing the generation of waste and is the highest target of the Swedish and European waste management. Nevertheless, the amount of waste continues to increase, and the projections made for the future show that volumes will continue to increase with the existing policy instruments. The purpose of this study is to investigate whether waste prevention measures can be ada

Oxytocin (OT) is a small neuropeptide, which is present in human plasma at extremely low endogenous levels of only a few pg/ml. It is mainly involved during labour and lactation but it has recently also been found that OT is involved in social behaviours like bonding and feeling empathy. During the last couple of years, the interest in OT has been raised and due to the matrix complexity, it is ver

Abstract: Serial dependence (SD) refers to the influence of a recent stimulus on a person’s perceptual judgement of a current stimulus. SD has been found to arise for a wide variety of objects and features, including faces. Perceptual and mnemonic processes, along with response and decisional biases, are thought to contribute to SD effects. Here, two experimental studies are reported examining the

In Sweden there are laws and recommendations from The National Board of Health and Welfare about the importance of a user's involvement in and possibility of influencing services directed at them. Even with such good intentions the same board reports that it is hard to know if people experience that they do. The purpose of my study was to examine how professionals can use their knowledge to he

The purpose of this thesis is to examine and analyze why, in the case of Afghanistan, the government chose to establish a highly centralized political system, when from a democratic standpoint a less centralized system would be preferable. The time period that is examined span from 2001 when the so-called Bonn-Accord was signed, to the parliamentary elections held in 2005, a period often referred

Problems: What is human capital? How is a knowledge worker’s human capital cultivated? In what way can an impresario help a knowledge worker to cultivate and capitalise on his or her human capital? Purpose: The purpose of this paper is to explore the impresario approach on talent with today’s knowledge workers and their human capital. A visualisation of such an approach might lead to ways of assis

Today plant-based alternatives to animal-agricultural products are made available or developed alongside ‘cultured’ meat, and products utilising genetic modification. To proponents, this signifies the emergence of ‘cellular agriculture’ as a food-production field or the possibility of a ‘post-animal bioeconomy’: a way to safely and sustainably produce animal products without animals. Drawing on pr

Alla ryggradsdjur har ett immunförsvar vars funktion är att skydda oss mot mikroorganismer som kan orsaka sjukdom, såsom bakterier och virus. Dessa sjukdomsframkallande ämnen kallas patogener. Immunförsvaret behöver kunna skilja mellan proteiner som kommer från den egna kroppen och från patogener. Molekylerna som kodas av gener i major histocompatibility complex (MHC) har en viktig del i denna igeThe function of the vertebrate immune system is to enable recognition and elimination of microorganisms that can cause harm (pathogens). A key component in adaptive immunity is the major histocompatibility complex (MHC) that codes for molecules with antigen presentation function. There are two main types of MHC molecules, class-I (MHC-I) and class-II (MHC-II) and the focus of my thesis has been MH

Attoscience is the emerging field that accesses the fastest electronic processes occurring at the atomic and molecular length scales with attosecond (1 as = 10−18 s) time resolution having wide ranging physical, chemical, material science and biological applications. The quintessential and one of the most fundamental processes in this domain is the generation of phase locked XUV attosecond pulses.

The upcoming Cherenkov Telescope Array (CTA) ground-based gamma-ray observatory will open up our view of the very high energy Universe, offering an improvement in sensitivity of 5-10 times that of previous experiments. NectarCAM is one of the proposed cameras for the Medium-Sized Telescopes (MST) which have been designed to cover the core energy range of CTA, from 100 GeV to 10 TeV. The final came

To date, research on warehouse order-batching has been limited by reliance on rigid assumptions regarding rack layouts. Although efficient optimization algorithms have been provided for conventional warehouse layouts with Manhattan style blocks of racks, they are limited in that they fail to generalize to unconventional layouts. This paper builds on a generalized procedure for digitization of ware