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Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.

Dyskinesia seen in the off-state, referred as graft-induced dyskinesia (GID), has emerged as a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. Although the mechanism underlying the appearance of GID is unknown, in a recent clinical study the partial 5-HT(1A) agonist buspirone was found to markedly reduce GID in three grafted patients, who showed signifi

Stories without significance in the discourse of breast reconstruction

Breast reconstruction is an everyday, apparently non-violent, even benevolent, remaking of the normal and the reasons for why reconstruction is motivated and legitimate are uncontroversial and widely accepted. In this article I will, through Donna Haraway’s way of conceptualizing discourses, analyze what I call “stories without significance”. I have mapped the stories and interpretations women und

Detailed numerical simulation of transient mixing and combustion of premixed methane/air mixtures in a pre-chamber/main-chamber system relevant to internal combustion engines

Transient mixing and ignition mechanisms in a simplified pre-chamber/main-chamber system are investigated using direct numerical simulation (DNS) with detailed chemical kinetics. Full ignition and flame propagation processes in the premixed methane/air mixtures are simulated. Ignition, the progress and topology of flame evolution, and the mean burning velocity in the main chamber are analyzed in d

Stubborn Swedes : The persistence of the Swedish corporate governance system under international reform

Despite a number of corporate governance reforms introduced following an Anglo-American blueprint, the Swedish corporate governance system still contains several country-specific traits. In this article, we try to understand this continuity of the national corporate governance system. We do this by outlining a model for describing the processes of change built on Mary Douglas’ (1986) theory of ‘inDespite a number of corporate governance reforms introduced following an Anglo-American blueprint, the Swedish corporate governance system still contains several country-specific traits. In this article, we try to understand this continuity of the national corporate governance system. We do this by outlining a model for describing the processes of change built on Mary Douglas’ (1986) theory of ‘in

Quantitative outcome measures for systemic sclerosis-related Microangiopathy – Reliability of image acquisition in Nailfold Capillaroscopy

Background Nailfold capillaroscopic parameters hold increasing promise as outcome measures for clinical trials in systemic sclerosis (SSc). Their inclusion as outcomes would often naturally require capillaroscopy images to be captured at several time points during any one study. Our objective was to assess repeatability of image acquisition (which has been little studied), as well as of measuremen

Tunable high-harmonic generation by chromatic focusing of few-cycle laser pulses

In this work we study the impact of chromatic focusing of few-cycle laser pulses on high-order-harmonic generation (HHG) through analysis of the emitted extreme ultraviolet (XUV) radiation. Chromatic focusing is usually avoided in the few-cycle regime, as the pulse spatiotemporal structure may be highly distorted by the spatiotemporal aberrations. Here, however, we demonstrate it as an additional

Brandprovning av gasolflaskor : Med respektive utan tryckavlastning

The purpose of this work was to experimentally examine the importance of safety devices (pressure valve and melting fuse) on propane bottles for consumer use (5 – 6 kg propane). The bottles tested included construction types based on composite (PK5, two different types), aluminum (PA6), and steel (P6). Bottles were tested with and without safety devices. The tests were made as a comparative study.

Understanding the pulse of existence : An examination of capurro’s angeletics

The contribution of Rafael Capurro to the clarification of the uses of the concept of information has a conceptual as well a historical dimension; in this last sense, there are few philosophers of information that can follow the history of the concept of information in the works of the Classics with the accuracy and erudition of Capurro We find that his contribution embraces the following fields:

Half-lives of PFOS, PFHxS and PFOA after end of exposure to contaminated drinking water

BACKGROUND: Municipal drinking water contaminated with perfluorinated alkyl acids had been distributed to one-third of households in Ronneby, Sweden. The source was firefighting foam used in a nearby airfield since the mid-1980s. Clean water was provided from 16 December 2013.OBJECTIVE: To determine the rates of decline in serum perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonate (PFOS) a

The economic burden of chronic obstructive pulmonary disease in the elderly : Results from a systematic review of the literature

Purpose of review: Chronic obstructive pulmonary disease (COPD) is a high prevalence condition with a significant clinical and economic burden. In elderly people, COPD is often associated with other chronic comorbidities (i.e. cardiovascular diseases), determining clinical complications and requiring frequent acute healthcare interventions. The aim of this article is to review the economic studies

Characterization of Hairdresser Exposure to Airborne Particles during Hair Bleaching.

Respiratory symptoms among hairdressers are often ascribed to the use of bleaching powders that contain persulfate salts. Such salts can act as allergens and airway irritants but the mechanisms behind the negative health effects are not fully known. In order to understand why some hairdressers experience respiratory symptoms during, and after, sessions of hair bleaching, it is of importance to cha

Tysk film efter muren. En tudelad historia

This article deals with German films after “die Wende”. The films studied are some of the most domestically successful in Germany, films that seldom found their way into the international market. The discussion shows how the narratives differed in films produced in the former East respectively West Germany, and that, among other things, the films often presupposed that the adaption process to a un

Laser Triggering of Electric Breakdown In Liquids

Electric breakdown in semihomogeneous geometries has been studied in n-hexane and transformer oil using a laser triggering method for fields far below the spontaneous breakdown field. The method uses a laser-produced plasma to initiate the breakdown. Strong self focusing in the liquids was limited by increasing the numerical aperture of the laser beam to > 0.20 prior to focusing. Electrical breakd

High Solids Waterborne Hybrid Systems: Effect of Surfactant Concentration and pH on Droplet Size and Morphology

Hybrid systems have been made by taking an acrylic latex dispersion and slowly dropping an alkyd resin into the dispersion while stirring to achieve a solid content of 75–80%. The particle size distributions of alkyd droplets were studied with a laser diffraction instrument and the structure of the hybrid system in the liquid state has been studied by light microscopy. The hybrid system was define

Admission control for Web server systems - design and experimental evaluation

In communication systems, all service control nodes, such as for example Web sites or mobile switching centers, can be modeled as a server system with one or more servers processing the incoming requests. To avoid overload at the service node some type of admission control mechanism is usually implemented to guarantee good performance also during high traffic loads. In this paper we investigate, f

EU-Asia and the re-polarization of the global economic arena

At the end of the 1980s, a tri-polar world comprising the US, EU and Japan emerged. However, the economic turbulence of the early 21st century has destabilized this order, and the rise of other Asian powers has implications for the formation of a new economic configuration. This book discusses the probability of the different tentative global economic power balances to emerge, as well as the diff

Time-stamping accuracy in virtualized environments

The swift acceptance and the widespread use of virtual environments has substantially increased the stress on networks as each of the operating systems running in parallel sends out packets over the same network. As an increased number of packets traverse a network, the importance to continuously monitor whether the network is providing satisfactory service has increased. The metrics for such anal

On the Ring-Opening Reaction of Thiophene-1,1-dioxides and the Intramolecular Diels-Alder Reaction of Azanona- and AzadecatrienesI

Substituted thiophene-1,1-dioxides were synthesized and their ring-opening reactions with omega-unsaturated secondary amines were investigated; this led to a synthetic route to azatrienes and to the preparation of some polyhydroisoindoles and polyhydroisoquinolines via an intramolecular Diels-Alder reaction. By using 2-substituted pyrrolidines and piperidines various tetrahydrobenzo[f]indolizidine