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Popular Abstract in Swedish Förr trodde man att de delar av genomet som inte uttrycks till proteiner är oviktiga, eftersom man trodde att det nästan uteslutande är proteinerna som utför de nödvändiga funktionerna i cellen. Man kände till att DNA och RNA innehåller information om hur proteiner ska se ut och när de ska uttryckas, men man kände bara till ett fåtal andra uppgifter som RNA har i cellen
Current market trends for industrial automation are the need for customizable production, shorter time to market, and powerful global competitive pressure. Based on these trends two challenges have been identified: 1) flexible production systems and 2) integration and utilization of devices and software. Applications from both process automation, manufacturing, and robotics have been considered.
This article aims to expand our understanding of projectification in Swedish municipalities. Above all the article explores to what extent processes of projectification can be identified and if so how they unfold. The article draws its inspiration from critical management studies and uses the notion of sensemaking to identify the practices of projectification processes. Three processes of projecti
Context: The dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits glucagon secretion at hyperglycemia but appears to enhance glucagon counterregulation during hypoglycemia in type 2 diabetes.Objective:The objective of the investigation was to study whether vildagliptin also improves α-cell function in type 1 diabetes (T1D). Patients and Methods: The study was a single-center, double-blind, ra
Attention is drawn to the feasibility of using high sensitivity isothermal heat conduction calorimetry to study metabolic responses of differently processed and stored fresh-cut fruit. The heat production of endogenous (tissue metabolism during 12 h of analysis at 10 degrees C for kiwifruit and strawberry) and exogenous (microbial growth during 18 d of analysis at 10 degrees C for cantaloupe) biol
Patients with Type 2 diabetes and coronary heart disease (CHD) are infrequently treated to risk factor targets in current guidelines. We aimed to examine risk factor management and control levels in a large sample of patients with Type 2 diabetes with CHD. This was an observational study of 1612 patients with first incidence of CHD before 2002, and of 4570 patients with first incidence of CHD befo
Background. In metastatic colorectal cancer, mutation testing for KRAS exon 2 is widely implemented to select patients with wild-type tumors for treatment with the monocloncal anti-EGFR antibodies cetuximab and panitumumab. The added predictive value of additional biomarkers in the RAS-RAF-MAPK and PI3K-AKT-mTOR pathways in colorectal cancer is uncertain, which led us to systematically review the
Compact SPECT systems with cadmium zinc telluride (CZT) solid-state detectors with improved energy resolution and shorter acquisition times have recently been introduced. These systems have, however, different energy characteristics compared to NaI(Tl) crystal-based cameras; therefore, a need exists to develop new simulation models for these cameras. We modeled the charge transport within the CZT
The objective of this work was to examine the atazanavir-bilirubin relationship using a population-based approach and to assess the possible application of bilirubin as a readily available marker of atazanavir exposure. A model of atazanavir exposure and its concentration-dependent effect on bilirubin levels was developed based on 200 atazanavir and 361 bilirubin samples from 82 patients receiving
The key role of tropical forest belowground carbon stocks and fluxes is well recognised as one of the main components of the terrestrial ecosystem carbon cycle. This study presents the first detailed investigation of spatial and temporal patterns of fine root stocks and fluxes in tropical forests along an elevational gradient, ranging from the Peruvian Andes (3020 m) to lowland Amazonia (194 m), w
Isomeric states in the semimagic Sn128-130 isotopes were populated in the fragmentation of a Xe-136 beam on a Be-9 target at an energy of 750 A.MeV. The decay of an isomeric state in Sn-128 at an excitation energy of 4098 keV has been observed. Its half live has been determined to be T-1/2 = 220(30) ns from the time distributions of the delayed gamma rays emitted in its decay. gamma gamma coincide
Sammanfattning I Europakonventionen artikel 8 skyddas rätten till privatliv. Varje person har rätt till skydd av personuppgifter som tillhör honom eller henne. Globalisering och teknologisk utveckling har anmärkningsvärt förändrat sättet på hur personuppgifter behandlas. En uppdaterad lagstiftning för personuppgiftsskydd behövs och EUs föreslagna förordning reflekterar tydligt utmaningarna för Summary The protection of personal data is a fundamental right in accordance with Article 8 of the European Convention of Human Rights. Every person has the right to the protection of information that concerns him or her. Globalisation and technological advancements have enormously transformed the way our personal data is collected. An updated legislation on data protection is needed and the pr
The Protogine Zone is a system of steep shear zones running approximately parallel to the boundary between the Svecofennian and the Southwest Scandinavian orogens of southern Sweden. The geological nature of the zone is not very well known, mainly because detailed mapping has not begun until recently. This work is the beginning of an attempt to start changing this situation. An area of l km², situ
Detta arbete handlar om en behandlingsteknik för hudterapi där lågenergetiska elektroner utnyttjas för strålbehandling där patienten står eller sitter på en roterande plattform. För att behandlingen skall få ett lyckat resultat krävs en viss stråldos (den absorberade energin per massenhet) till patientens hud. För att kontrollera att dosen är rätt används normalt mätningar med olika detektorer. DeBackground and purpose: This study refers to a rotational radiotherapy technique for the treatment of mycosis fungoides. Patients are irradiated by a high dose-rate low-energy electron beam while they stand on a rotating platform. This report presents a first effort to use the Geant4 simulation program to calculate the relation between the stationary and rotational depth dose distributions in an e
Technical assistance to public sector organisations is a much-debated topic and showcases a considerable size in contemporary international development assistance. Yet, the empirical evidence base on which factors contribute to the outcomes of projects within this field is surprisingly slim and diffuse. Particularly, the mechanisms through which different factors affect project outcomes remains un
This essay is about a deserted medieval habitation called Skyttsie Hage which is located in the south of Sweden in the Scania province where it lies on a moor on the Falsterbopeninsula. Remains of five to six larger buildings have been found here with a surrounding earthwork, although it's not known for sure what kind of habitation they have been part of. Local folklore from the 17:th century
Abstract In this thesis I have discussed the ongoing international state-building mission in Kosovo in the context of the final status issue and examining the future prospects. The main question of this study has been in which direction the state-building process is moving Kosovo and whether it can be regarded as a success or a failure. This qualitative case study has employed the ?institutional
We have made a thesis about Collaboration for Innovation in the Öresund region from a Swedish perspective. The thesis is taking both regional and corporate aspects into consideration when studying this subject. The empiric material is based upon several interviews with persons having knowledge about our subject as well as a web survey including 49 companies situated in the Öresund region. We have
