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This Study has been carried out in co-operation with SJ AB, Banverket, Västtrafik and the department for Production Management and Economics at the Faculty of Engineering of the Lund University, LTH. The Study has been based on a requirement specification from SJ AB, (the major railway traffic operator in Sweden). The objective of the study is to: · clarify the importance of methodically working w
The thesis idea originated from that the authors experienced that they would have liked to have more opportunities to apply their educational and personal skills before attending the business world. The authors found a way to accomplish this by the application of a multidiscipline case simulation. The purpose of this master’s thesis is to test an idea and the application of the same. Another purpo
Skattetilläggsbestämmelserna och skatteflyktslagen utgör var för sig till viss del kontroversiella metoder för att skydda den svenska skattebasen. Skatteflyktslagen infördes till att börja med som medel för att åstadkomma en jämlik och korrekt beskattning i fall då de skattskyldige på ett lagenligt vis kringgått skattebestämmelser. Som tiden gått har skatteflyktslagen fått ett utvidgat tillämpningThe regulations on tax surcharge and the Tax Evasion Act are both considered to be controversial ways of protecting the Swedish tax base. The Tax Evasion Act was passed in order to achieve an equal and correct taxation even though the taxpayer in a legal way has evaded tax. Over the years the scoop of application of the Tax Evasion Act has increased and with the ruling in the case RÅ 2010 ref. 51
Populärvetenskaplig sammanfattning: Naturbetesmarkerna minskade med 86,7% från 1927 till 1990. Denna minskning är alarmerande eftersom många idag hotade och sällsynta arter är beroende av dessa. En stor del av anledningen till detta är att staten ända in på 1980-talet i sin rådgivning danade för att dessa marker antingen skulle bearbetas med konstgödsel och ogräsbekämpning eller planteras med trädThe rural landscape of Sweden has changed rapidly during the 20:th century. Measurements from 1927 compared to those from 1990 show that the area of non managed pasture in Sweden has declined by 86.7 %. Since a lot of threatened and rare species are dependent of this kind of land, these figures are alarming. During the last 30-40 years non managed pasture has declined due to abandonment, tree plan
An association between high Galectin-4 (Gal-4) and prevalence of diabetes in subjects with heart failure (HF) has previously been reported. The purpose of this study was to confirm these findings, as well as to further investigate this association, in a Swedish HF population. In addition, a second aim was to explore Gal-4’s association with obesity and biomarkers of metabolism and heart failure. G
Background: Synaptic dysfunction and degeneration are central contributors to the pathogenesis and progression of parkinsonian disorders. Therefore, identification and validation of biomarkers reflecting pathological synaptic alterations are greatly needed and could be used in prognostic assessment and to monitor treatment effects. Objective: To explore candidate biomarkers of synaptic dysfunction
Flame front structure is one of the most fundamental characteristics and, hence, vital for understanding combustion processes. Measuring flame front structure in turbulent flames usually needs laser-based diagnostic techniques, mostly planar laser-induced fluorescence (PLIF). The equipment of PLIF, burdened with lasers, is often too sophisticated to be configured in harsh environments. Here, to sh
Winter cover crops could contribute to more sustainable agricultural production and increase resiliency to climate change; however, their adoption remains low in California. This paper seeks to understand barriers to winter cover crop adoption by monetizing their long-term economic and agronomic impacts on farm profitability in two of California's specialty crop systems: processing tomatoes and al
Most stomatopod crustaceans have complex retinas in their compound eyes, with up to 16 spectral types of photoreceptors, but members of the superfamily Squilloidea have much simpler retinas, thought to contain a single photoreceptor spectral class. In the Atlantic stomatopod Squilla empusa, microspectrophotometry shows that all photoreceptors absorb light maximally at 517 nm, indicating that a sin
Background: Pelvic exenteration for locally advanced rectal cancer (LARC) and locally recurrent rectal cancer (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes of exenteration over time.Methods: This was a multicentre retrospective study of patients who underwent exenteration for LARC and LRRC between 2004 and 2015. Su
Background: Environmental and genetic factors possibly trigger thyroid autoimmunity. Studies on perinatal risk factors for childhood thyroid autoimmunity are sparse.Objectives: The aim was to investigate if perinatal factors, family history of autoimmune diseases, and HLA-DQ genotypes contribute to thyroid autoimmunity in the Diabetes Prediction in Skåne (DiPiS) study.Methods: Samples from 1,874 t
Background: A dysregulated postprandial metabolic response is a risk factor for chronic diseases, including type 2 diabetes mellitus (T2DM). The plasma protein N-glycome is implicated in both lipid metabolism and T2DM risk. Hence, we first investigate the relationship between the N-glycome and postprandial metabolism and then explore the mediatory role of the plasma N-glycome in the relationship b
Deciding the optimal project scope that fulfills the needs of the most important stakeholders is challenging due to a plethora of aspects that may impact decisions. Large companies that operate in rapidly changing environments experience frequently changing customer needs which force decision makers to continuously adjust the scope of their projects. Change intensity is further fueled by fierce ma
OBJECTIVES: Genomewide association studies (GWAS) have identified consistent associations with obesity, with a number of studies implicating eating behavior as a primary mechanism. Few studies have replicated genetic associations with dietary intake. This study evaluates the association between obesity susceptibility loci and dietary intake. METHODS: Data were obtained as part of the Diabetes Prev
Optical measurement techniques have proven to be useful tools for studying combustion-related phenomenon. The fact that the techniques are optical facilitates performing the measurements without impinging upon the measurement object, such as the combustion event that can be involved. Such techniques can be species-specific and be performed in situ, i.e. in the setting in which the phenomena in que
Introduction: ECG-derived vectorcardiography (VCG) has diagnostic and prognostic value in various diseases. Hypertrophic cardiomyopathy (HCM), a genetic disease with unexplained left ventricular hypertrophy, is one of the most common causes of sudden cardiac death (SCD) in young persons. Genotype positive status is associated with increased risk of systolic dysfunction, heart failure, and (SCD). H
Aim: The aim of this study is to evaluate the quality of data on endometrial (EC) and ovarian, fallopian tube, peritoneal, abdominal or pelvic cancers (OC) registered in the Swedish Quality Register of Gynecologic Cancer (SQRGC). Method: A random sample of 500 patients was identified in the SQRGC and their medical charts were reviewed for re-abstraction of 31 selected core variables by an independ
The increased demand for high purity nanoparticles (NPs) of defined geometry necessitates the continuous development of generation routes. One of the most promising physical techniques for producing metal, semiconductor or alloy NPs in the gas phase is spark discharge NP generation. The technique has a great potential for up-scaling without altering the particles. Despite the simplicity of the set
