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The PEFC has emerged as the most viable fuel cell type for automotive and some portable applications, and also has potential back-up power unit applications due to its low operating temperature, comparative simplicity of construction, high power density, and ease of operation. In spite of tremendous scientific advances, as well as engineering progress over the last few decades, the commercializati
Background and Purpose-Hematoma volume is an important determinant of clinical outcome in spontaneous intracerebral hemorrhage (ICH). We performed a genome-wide association study (GWAS) of hematoma volume with the aim of identifying novel biological pathways involved in the pathophysiology of primary brain injury in ICH. Methods-We conducted a 2-stage (discovery and replication) case-only genome-w
Giant planets migrate though the protoplanetary disc as they grow their solid core and attract their gaseous envelope. Previously, we have studied the growth and migration of an isolated planet in an evolving disc. Here, we generalise such models to include the mutual gravitational interaction between a high number of growing planetary bodi
BACKGROUND: Hyperthyroidism is known to have a significant impact on quality of life (QoL), at least in the short term. The purpose of the present study was to assess QoL in patients 6-10 years after treatment for Graves' disease (GD) with radioiodine (RAI) compared to those treated with thyroidectomy or antithyroid drugs (ATD) as assessed with both thyroid-specific Thyroid-Related Patient-Reporte
Popular Abstract in Swedish Gränsvärden för NOX-utsläppen i avgaserna från tunga dieselmotorer kommer att minskas i den Europeiska Unionen från 3,5 g/kWh (Euro IV) idag till 2,0 g/kWh (Euro V) år 2008. I USA och Japan är trenden likadan och utveckling av ett avgassystem för tunga dieselfordon verkar oundviklig. I detta arbetet har en motorrigg byggts upp som bestod av en 11 l dieselmotor och ett aThe legislative limits for NOX emissions in the exhaust gas from heavy-duty diesel engines will be decreased in the European Union from today 3.5 g/kWh (Euro IV) to 2.0 g/kWh in 2008 (Euro V). In the USA and Japan a similar trend can be seen. Accordingly, the development of an exhaust aftertreatment system for heavy-duty trucks seems unavoidable. In this work, an 11 l diesel engine rig has been bu
Background: The prevalence of obesity is increasing worldwide and prevention is needed. Whole grain has shown potential to lower the risk of obesity, cardiovascular disease and type 2 diabetes. One possible mechanism behind the benefits of whole grain is the gut fermentation of dietary fiber (DF), e.g. non-starch polysaccharides and resistant starch (RS), in whole grain. The purpose of the study i
Popular Abstract in Swedish Många åtminstone i min generation kommer säkert ihåg att de under gymnasiets biologilektioner fick lära sig att vatten diffunderade fritt över cellens membran ? osmos och fri diffusion var ledorden. Jag vet inte hur läroböckerna är utformade idag, men efter att Nobelpriset i kemi år 2003 tilldelades Peter Agre för upptäckten av att aquaporiner fungerar som vattenkanalerIn order to identify integral and peripheral proteins associated with the plasma membrane (PM), highly purified Arabidopsis PMs were analyzed by mass spectrometry. In total, 238 putative PM proteins were identified, of which 114 were predicted to have transmembrane domains or to be PM-anchored. Identified proteins were involved in transport, signal transduction, membrane trafficking and stress res
Popular Abstract in Swedish Ett material som utsätts för varierande last, även under gränslasten för statisk kollaps, riskerar att utveckla sprickor som i sin tur kan orsaka brott. Denna typ av materialnedbrytning kallas utmattning och är ett ständigt aktuellt forskningsområde. Väldigt korta sprickor är kända för att växa på ett sätt som avviker från hur längre utmattningssprickor beter sig, ävenThe growth of short fatigue cracks deviates from the behaviour of long fatigue cracks even if subjected to the same nominal driving force. The influence from the microstructure is pronounced, while crack closure effects may not be that important as for longer cracks. The objective of this thesis is to study the local conditions for crack growth for two different short crack problems, and to develo
The aim was to gain knowledge of young people's physical status and physical activity, and to further the understanding of the role of school physical education in a salutogenic public health perspective. Two studies were performed in southern Sweden. Study 1 was performed in 1996 among 301 adolescents aged 16-19 in upper secondary school. It comprised three parts: a questionnaire, seven physical
Popular Abstract in Swedish Kritiskt sjuka patienter på intensivvårdsavdelningar (IVA) har ofta störningar i blodets levringsförmåga (koagulation). Kliniska tecken som blodpropp (djup ventrombos eller blodpropp i lungorna) och/eller blödning kan vara resultatet av aktivering och konsumtion av koagulationsfaktorer och koagulationshämmare. Disseminerad intravaskulär koagulation (DIC, som är en samtiCritically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. Global haemostatic tests are inexpensive, widely available, and ma
Popular Abstract in Swedish Avregleringen av elmarknaden uppmuntrar kraftbolag och oberoende kraftproducenter till att driva sina kraftverksanläggningar på ett marknadsorienterat sätt. För att behålla de ekonomiska marginalerna på plussidan så har de mest populära åtgärderna varit att förbättra elverkningsgraden genom ändringar i hårdvaran samt höja totalverkningsgraden genom till exempel samproduThe deregulation of the electricity market drives utilities and independent power producers to operate heat and power plants as profit centers. In order to keep the economic margins on the credit side, the preferred measures have been to improve the electrical efficiency through changes in the hardware and boost the overall efficiency through e.g. combined heat and power (CHP) generation. The bett
Background Analysis of the Swedish Farmacotherapy (Swefot) trial at 12 months showed that the addition of an anti-tumour-necrosis-factor agent gave an improved clinical outcome compared with the addition of conventional disease-modifying antirheumatic drugs in patients with methotrexate-refractory early rheumatoid arthritis. Here we report the 2 year follow-up assessment. Methods In this randomise
OBJECTIVE: The influence of the gastrointestinal (GI) microflora in patients with irritable bowel syndrome (IBS) has not been clearly elucidated. This study was undertaken to see if patients with IBS have an imbalance in their normal colonic flora, as some bacterial taxa are more prone to gas production than others. We also wanted to study whether the flora could be altered by exogenous supplement
Background: Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be generally well tolerated and efficacious in reducing OFF-time in two pivotal trials in patients with PD and end-of-dose motor fluctuations. The OpiCapone Effect on motor fluctuations
Galactic Archaeology is the study of the formation and evolution of the Milky Way through the properties of stars and stellar populations. The combination of stellar ages, chemical compositions, positions, and velocities can reveal the history of star formation and chemical enrichment in different regions of the Galaxy. A large number of stellar spectroscopic, photometric, and astrometric surveys
BACKGROUND: Critically ill newborn infants undergo a variety of painful procedures or experience a variety of painful conditions during their early life in the neonatal unit. In the critically ill paediatric and neonatal population, clonidine is prescribed as an adjunct to opioids or benzodiazepines aiming to reduce the doses of these drugs that are required for analgesia or sedation, or to facili
Popular Abstract in Swedish Varje vecka firar ett stort antal människor gudstjänst i Svenska kyrkan. Vid varje enskild gudstjänst bildas en sorts gemenskap. Men vad är egentligen en gudstjänstgemenskap, hur kan den förstås sociologiskt och teologiskt, vilken ställning har den i Svenska kyrkan och vilken ställning borde den ha? Gudstjänstgemenskaper i Svenska kyrkan i dag kan beskrivas som öppna, iThe dissertation examines the theoretical identity and formal status of a worship community within the Church of Sweden. Two theoretical perspectives form the basis of the investigation. The first is that the identity of the church cannot be reduced to an abstract idea of its essential nature, but what is said about the church must refer to the actual people who belong to it, especially those who
Background: The benefits of exercise in mild and moderate knee or hip osteoarthritis (OA) are apparent, but the evidence in severe OA is less clear. We recently reported that neuromuscular training was well tolerated and feasible in patients with severe primary hip or knee OA. The aims of this controlled before-and-after study were to compare baseline status to an age-matched population-based refe
The rationale for thrombolysis, the most promising pharmacological approach in acute ischaemic stroke, is centred on the principal cause of most ischaemic strokes: the thrombus that occludes the cerebral artery, and renders part of the brain ischaemic. The occluding thrombus is bound together within fibrin. Fibrinolysis acts by activation of plasminogen to plasmin; plasmin splits fibrinogen and fi
Aims. The nature of the thick disc and its relation to the thin disc is presently an important subject of debate. In fact, the structural and chemo-dynamical transition between disc populations can be used as a test of the proposed models of Galactic disc formation and evolution. Methods. We used the atmospheric parameters, [alpha/Fe] abundances, and radial velocities, which were determined from t
