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Popular Abstract in Swedish Populärvetenskaplig sammanfattning Felaktig DNA-reparation av typen mismatch repair (MMR) uppkommer i 15-17% av cancer i tjock- och ändtarm (kolorektalcancer). MMR defekter är av betydelse i tre situationer: • MMR defekta tumörer har en bättre prognos än övrig tjock- och ändtarmscancer, vilket kan användas för att avgöra huruvida en patient skall erbjudas sk. adjuvant Mismatch repair (MMR) deficiency is carcinogenic and can either have somatic/sporadic causes (i.e. epigenetic silencing or somatic inactivation) or hereditary causes (Lynch syndrome due to a germline mutation in one of the MMR genes ¬- MLH1, MSH2, MSH6, PMS2). The identification of MMR defective colon cancer is clinically relevant for diagnostic, prognostic and potentially also for treatment-predi

Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet

This thesis examines the enforcement of art 101 TFEU by the European Commission through the lens of the Charter, in particular, art 48(1) thereof which provides for the presumption of innocence. The fact that the fines imposed by the Commission in competition proceedings are considered to be ‘criminal charges’ by the ECtHR seems to have been settled for quite some time now. Granted, the EU has not

Boreal and temperate forests have been greatly affected by clear-cutting. Alternative management systems, such as continuous cover forestry and selective logging, have remained secondary to the dominant even-aged management regime. This regime has its roots in scientific forest management, whose dissemination and development have been well described. But the experiences of rural communities living

This paper deals with the disputable issue of the existence of Malthus’ Preventive Check in Chinese population. With the help of a newly established historical database (Demographic Database of Colonial Taiwan, DDCT), which currently including the individual level data regarding to the socio-demographic backgrounds of the registered population in fifteen townships in North and Western Taiwan, we t

Microsoft Word - Kallelse årsmöte 2020.docx KALLELSE Ledamöterna i Saco-S-rådet vid Göteborgs universitet kallas till ordinarie årsmöte Tisdag den 26 maj 2020 kl 15:45 Plats: Mikael Brisslert is inviting you to a scheduled Zoom meeting. Topic: Årsmöte Saco-S Time: May 26, 2020 03:45 PM Stockholm Join Zoom Meeting https://gu- se.zoom.us/j/66968855936?pwd= TGNaMWVRRk96VlVmNlFyTEZT Umh6QT09 Meeting I

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/goteborgs-universitet/dokument/kallelse-dagordning-och-zoom-lank20201.pdf - 2026-07-24

The underwater noise has a significant negative impact on marine animals. The EU has made efforts to keep noise emission within sustainable limits, but only in regards to boats with Automatic Identification System (AIS). The noise of recreational boats, which are the main noise emitter in coastal areas, is overlooked. Thus, there is a need to quantify the noise emitted by recreational boats and, i

CAT bonds allow institutions to transfer insurance exposure from their balance sheet onto the capital market to hedge against catastrophe-linked payment obligations. For investors in the capital markets, CAT bonds are, at least theoretically, a means of employing capital to earn a return that is uncorrelated with alternative investments. Grounded in this theoretical approach, we investigate the po

Popular Abstract in Swedish By building a strong brand that is favourably perceived by target customers, a firm can establish a competitive advantage that enables greater revenues and profitability. This is at least what the branding literature always has assumed, and something few marketing and brand managers seem to disagree with. When asked how exactly a brand can be charged with such great valBy building a strong brand that is favourably perceived by target customers, a firm can establish a competitive advantage that enables greater revenues and profitability. This is at least what the branding literature always has assumed, and something few marketing and brand managers seem to disagree with. When asked how exactly a brand can be charged with such great value, however, neither academi

Popular Abstract in English This thesis provides new insights into parents’ patterns of daily occupations. It proceeds from the basis of an occupational perspective on family life, using an occupational lens to understand how, when and where individuals spend their time. In recent decades, lifestyles have changed worldwide and the transition into an increasingly sedentary lifestyles is a major heaThis thesis provides new insights into parents’ patterns of daily occupations. It proceeds from the basis of an occupational perspective on family life, using an occupational lens to understand how, when and where individuals spend their time. In recent decades, lifestyles have changed worldwide and the transition into an increasingly sedentary lifestyles is a major health concern, the origins whi

Objective: To evaluate under- and overreporting and their determinants in the EPIC :24-hour diet recall (24-HDR) measurements collected in the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: Cross-sectional analysis. 24-HDR measurements were obtained by means of a standardised computerised interview program (EPIC-SOFT). The ratio of reported energy intake (EI) to estim

Dissolved organic carbon (DOC) plays a key role in linking terrestrial and aquatic carbon cycles. Most of the work on soil and water DOC has been conducted in temperate watersheds. There is still a gap in knowledge on DOC dynamics within the tropics. This study assesses water extractable organic carbon (WEOC) in topsoils and describes the relationship between WEOC and land use/land cover (LULC), s

At self-similarity the strain history is implicit in and deducible from the strain field at each instance of the loading process. This fact is taken advantage of in a FEM-technique which allows the load to be applied in one single step, only, even when the incremental theory of plastic flow has to be used. Two self-similar problems are solved. Firstly an analytically solvable anti-plane strain craAt self-similarity the strain history is implicit in and deducible from the strain field at each instance of the loading process. This fact is taken advantage of in a FEM-technique which allows the load to be applied in one single step, only, even when the incremental theory of plastic flow has to be used.Two self-similar problems are solved. Firstly an analytically solvable anti-plane strain crac

Air pollution is recognized as the most important environmental factor that adversely affects human and societal wellbeing. Due to rapid urbanization, air pollution levels are increasing in the Sub-Saharan region, but there is a shortage of air pollution monitoring. Hence, exposure data to use as a base for exposure modelling and health effect assessments is also lacking. In this study, low-cost s

At synchrotron light storage rings there is demand for serving high-brilliance users requesting multibunch operation while simultaneously serving timing users who require single-bunch operation. One method to accomplish this is PPRE developed and currently in user operation at BESSY II. In the method, the transverse emittance of one of the bunches in the bunch train is increased by an incoherent b

Context. Parallaxes for 331 classical Cepheids, 31 Type II Cepheids, and 364 RR Lyrae stars in common between Gaia and the Hipparcos and Tycho-2 catalogues are published in Gaia Data Release 1 (DR1) as part of the Tycho-Gaia Astrometric Solution (TGAS). Aims. In order to test these first parallax measurements of the primary standard candles of the cosmological distance ladder, which involve astrom

Purpose: The purpose of this study was to explore the relationship between oxidative stress, antioxidant defense, mitochondrial structure, and biomechanical tissue support in the isolated porcine retina.Methods: Full-thickness retinal sheets were isolated from adult porcine eyes. Retinas were cultured for 2 or 48 h using (1) a previously established low-support explant protocol with photoreceptors