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The interferon inducible protein TRIM22 has been identified as a p53 target gene, with possible involvement in proliferation and differentiation of leukaemia cells. Here, the expression levels of TRIM22 during haematopoietic differentiation are characterised. Expression of TRIM22 correlates inversely to differentiation, as TRIM22 is highly expressed in CD34(+) human bone marrow progenitor cells, b

Background and aims: In the elderly, balance and walking impairments are assumed to play an important role in causing falls. We have assessed prospectively the predictive ability of health, function and balance variables regarding falls and their location. Methods: Falls which occurred during one year in a random sample of 307 women aged 75 years and over (mean 80.8 years, response rate 74.5%) liv

The previous round-robin (RR) study on clothing evaporative resistance (Ret) has shown that the repeatability and reproducibility of clothing Ret measurements on sweating manikins were rather low. To further examine and enhance the measurement accuracy, a new strict but feasible test protocol was proposed and thoroughly examined in a new round-robin test. Eight laboratories participated in this st

Popular Abstract in Swedish Beräkningar från Cancerfonden visar på att ungefär var tredje person i Sverige kommer att få en cancerdiagnos under sin livstid. Cancerceller är celler som har utvecklat speciella förmågor som gör att de har börjat dela sig ohämmat. Denna ohämmade celldelning leder till bildandet av en tumör och när tumören har nått ett visst stadie i sin utveckling så börjar den spridaAs a cancer grows it will, at a certain stage of disease progression, start spreading in the body. For several types of cancer this spreading will first occur through the lymphatic system and the first place where metastatic cell will be encountered is the first lymph node that drains the area where the tumor is located. This lymph node is defined as the sentinel lymph node (SLN). By analyzing the

Aim To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology. Methods A majority of all ambulance organizations in Sweden (covering 85% of Sweden inhabitants) participate in a National survey of out of hospital cardiac arrest. Results I

Popular Abstract in Swedish Allt levande består till stor del av proteiner. De bygger upp muskler och hår, transporterar syre i blodet och ser till att kemin i kroppen fungerar som den ska. Men hur tillverkas då dessa proteiner? Jo i alla celler finns ribosomer, proteinfabriker. En bakterieribosom är ungefär 0.02 mikrometer stor. Den är sammansatt av proteiner och RNA-kedjor. RNA utgör den funktioTranslation is a central biological process, that is catalysed by a machinery consisting of RNA and protein. In this thesis three different protein components of the bacterial protein synthesis system have been structurally studied. Ribosome recycling factor (RRF) is essential for the recycling step of the translation cycle, elongation factor SelB is a specialised elongation factor needed for co-t

OBJECTIVE: To investigate feasibility and target engagement of high-dose, add-on pramipexole treatment in anhedonic depression.METHOD: In this open-label pilot study, we included 12 patients with unipolar or bipolar, moderate-to-severe depression and with significant anhedonia symptoms. All patients were on a stable dose of one or a combination of antidepressants and/or mood stabilizers and receiv

Antibody microarrays are becoming increasingly established in clinical studies. However, the arrays are seldom used in a quantitative approach but rather for detecting up or down regulated proteins. In this study we describe a microarray procedure being standardized by placing the in-house developed porous silicon surfaces into a commercially available 96 well microtiter plate for analyzing the PS

Forskare vid Lunds universitet har utvecklat en lovande nanoteknikbaserad metod för att leverera biomolekyler till mänskliga blodstamceller. Metodens förmåga att bibehålla cellernas funktion utan någon negativ påverkan har stor potential inom både grundforskning och kliniska tillämpningar. Här beskrivs den nya kunskapen av forskarna Ludwig Schmiderer, Jonas Larsson och Martin Hjort vid Lunds unive

1 URVALSPROV MKULÄ 191107 1. En 75-årig kvinna med primär biliär cholangit (PBC) sedan många år och endast sporadiska kontakter med vården utom receptförnyelser av Ursofalk söker akut på akuten på grund av hematemes. Hennes partner beskriver en successiv avtackling med trötthet och förvirring de senaste månaderna. I lab ses ett spontant förhöjt PK på 1,9, trombocyter 85, albumin 28 men normala tra

https://www.medicin.lu.se/sites/medicin.lu.se/files/facit_urvalsprov191107.pdf - 2026-05-27

Under 1800-talets första hälft antog samtliga skandinaviska länder nya för-fattningar. Sverige var först med 1809 års regeringsform (RF) och 1810 års riksdagsordning (RO), följt av Norge genom 1814 års grundlag och slutligen Danmark med 1849 års grundlag. Författningarna tillkom under en period präglad av omfattande utveckling inom den statsteoretiska forskningen. En av de filosofer som bidrog tilDuring the first half of the nineteenth century new constitutions were adopted in all Scandinavian countries. Sweden introduced the 1809 Instrument of Government, followed by the Norwegian Constitution of 1814 and the Dan-ish Constitution of 1849. These constitutional reforms took place during a time of significant development in constitutional theory. One of the theorists who contributed to these

This Bachelor’s degree project investigates how to create a modular chair system. It should let the consumer combine different parts to create a chair that fits their home, style and needs. The focus is on how a low number of parts can be used in different ways to create differentcombinations. It should also be easy to replace and recycle all parts when needed. This document shows the full design

Ny teknik hjälper till att svara på gamla frågor - Flyttfågelrörelser kartläggs med hjälp av minimala dataloggar I alla tider har man fascinerats över flyttfåglars förmåga att genomresor som sträcker sig över kontinenter följa säsongernas cykler. Att anlända i rätt tid för att kunna utnyttja sommarens överflöd av resurser för att lika flyktigt, ge sig av när höstmörkret närmar sig är vad många f1. Migratory birds show predictable annual routines, divided in breeding and wintering in separate areas and migration in-between. For obligate insectivorous birds this includes continental-wide journeys. How birds perform these schedules and how they time their use of space is not well understood. 2. I have used geolocator-derived data to describe the non-breeding movement of 14 individually tra