Filetype
OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>
Objective Blood cell populations, including red blood cells (RBC) unique to the extremely preterm (EPT) infant, are potentially lost due to frequent clinical blood sampling during neonatal intensive care. Currently, neonatal RBC population heterogeneity is not described by measurement of total haemoglobin or haematocrit. We therefore aimed to describe a subpopulation of large RBCs with hyper high
BackgroundA novel non-invasive method for generation of pressure volume loops (PV-loops) using brachial blood pressure and cardiovascular magnetic resonance (CMR) imaging has recently been presented and validated (1). The non-invasive nature of this method enables calculation of PV-loops in large patient cohorts previously not feasible due to the need of invasive measurements.PurposeThe purpose of
In this group we study how metastatic processes depend on suppression of the immune response and how the immune system actually instead promotes breast cancer metastasis. The research has a strong translational character with clinical collaborations and primary material as base in all projects. The focus is on immunosuppressive cell populations and metastatic processes in breast cancer. Understand
Our research is focused on the regulation of the complement system in health and disease. Complement is crucial part of innate immunity and thus protects host from infections and contributes to removal of dying cells. We study involvement of complement in pathology of rheumatic and inflammatory diseases as well as several types of cancer. Further, we investigate strategies developed by bacterial
The aim of this thesis is to explore what impacts the IDF’s Military Orders regarding water have on Palestinians in the West Bank, taking international humanitarian law (IHL) and International Convention on Civil and Political Rights (ICCPR) into consideration. Thus, to discover whether or not Israel’s actions are compatible with IHL and treats everyone equal before the law, as stated in ICCPR Art
Background: Under inflammatory conditions, T cell-dependent (TD) protein antigens induce proinflammatory T-and B-cell responses. In contrast, tolerance induction by TD antigens without costimulation triggers the development of regulatory T cells. Under both conditions, IgG antibodies are generated, but whether they have different immunoregulatory functions remains elusive. Objective: It was shown
