Filetype
Background: The worries of next of kin about their older loved ones in nursing homes can be extensive and can adversely affect their subjective experiences of their own physical, mental and social well-being. It is thus of utmost importance to measure the quality of life of next of kin in a valid and reliable way. Methods: The design is a cross-sectional study with psychometric evaluation based on
Background: Online gambling has increased in recent years, including online casino games and live sports betting which constitute rapid gambling activities with significant potential for gambling-related harm. There is a paucity of research examining whether specific gambling patterns are related to problem gambling and over-indebtedness, when controlling for psychological distress, gender, and ot
Objective: To determine factors associated with higher degree of meniscal body extrusion in overweight and obese women at high risk of knee osteoarthritis (OA). Design: We used baseline data of the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study, Netherlands, comprising overweight or obese women aged 50-60 years, free of clinical knee OA. All subjects completed a questionnair
We investigated the relationship between nitric oxide (NO) and Na+,K+-ATPase (NKA) in the gill of anadromous Atlantic salmon. Cells containing NO-producing enzymes were revealed by means of nitric oxide synthase (NOS) immunocytochemistry and nicotinamide adenine dinucleotide phosphate diaphorase (NADPHd) histochernistry, which can be used as an indicator of NOS activity, i.e. NO production. Antibo
Introduction: Soft tissue knee injury is a well-established and potent risk factor for development of knee osteoarthritis. However, there is a paucity of epidemiological data from the general population. Our aim was to estimate the annual person-level incidence for a wide spectrum of clinically diagnosed soft tissue knee injuries, and their distribution by age, sex, and season. Methods: In Sweden,
The introduction of L-DOPA pharmacotherapy revolutionized the treatment of Parkinson’s disease close to fifty years ago. Before the discovery of dopamine as a neurotransmitter and its involvement in the disease, these patients had very little aid from medication and were bound to a life without movement. The dopamine neurons in the midbrain are a key player in the circuitry that is responsible for
Popular Abstract in Swedish Nervsystemet är sannolikt en av de mest vidunderliga strukturer som skapats i detta universum - denna avhandling hade till exempel varken kunnat skrivas eller läsas utan det. Som av en slump handlar den också om just nervsystemet och läsande och skrivande är två exempel på olika funktioner som möjliggjorts på grund av det. Även om dessa utgör funktioner som är ovanliga Bodies with multiple limbs and joints have endless possibilities to move around in their surrounding space. How the nervous system controls this amount of degrees of freedom in motor execution is a question under vigorous debate. In an ambition to explore related aspects of motor control we conducted parallel electrophysiological recordings of motor circuits in the cortex and basal ganglia in the
PURPOSE: As a prelude to developing updated, evidence-based, international consensus recommendations for the management of hip and knee osteoarthritis (OA), the Osteoarthritis Research Society International (OARSI) Treatment Guidelines Committee undertook a critical appraisal of published guidelines and a systematic review (SR) of more recent evidence for relevant therapies. METHODS: Sixteen exper
OBJECTIVES: To evaluate the outcome of treatment for deep sternal wound infection (DSWI) in a nationwide patient cohort, before and after the introduction of negative-pressure wound therapy (NPWT). METHODS: This was a population-based cohort of all patients treated for DSWI in Iceland out of 2446 open heart operations performed between 2000 and 2010. Length of hospital stay, survival and reoperati
Prior work demonstrated increased levels of hypoxia-inducible factor-1α (HIF-1α) in the bladder following outlet obstruction, associated with bladder growth and fibrosis. Here we hypothesized that HIF induction in outlet obstruction also switches energetic support of contraction from mitochondrial respiration to glycolysis. To address this hypothesis, we created infravesical outlet obstruction in
Since the feminist movement developed today, women still face the challenges of gender inequality. In some countries, women even cannot see the hope for change. Hence, when aiming to counteract gender inequality, it is important to address the macro level and the micro level. The research focuses on the micro level of resistance to gender inequality instead of large-scale protest movements to exp
I denna uppsats har psykiskt störda lagöverträdares ansvarsförutsättningar i svensk- respektive dansk rättsordning undersökts. Sveriges val, att i samband med brottsbalkens införande 1965, avskaffa tillräknelighetsbestämmelserna, har genom åren mött en hel del kritik. Uppsatsen avser att besvara frågan kring huruvida ett tillräknelighetsrekvisit bör återinföras i svensk lagstiftning eller ej. DåThis thesis examines the conditions of liability for mentally disturbed offenders in the legal systems of Sweden and Denmark. Sweden’s decision to abolish the insanity defense provisions upon the introduction of the Penal Code in 1965 has faced considerable criticism over the years. This study aims to address whether a legal requirement for criminal accountability should be reintroduced into Swedi
Individuals with immigrant background generally perform less well in school than non-immigrants. Performing well in school may decrease the risk of substance use disorder (SUD). We investigated whether higher school performance is associated with a decreased risk of SUD in early adulthood among immigrants and non-immigrants and whether subsequent educational attainment and employment status partly
BACKGROUND: Pediatric cancer diagnosis and treatment reduce Health-Related Quality of Life (HRQoL). The Pediatric Quality of Life (PedsQL) Cancer Module is the most commonly used cancer specific HRQoL instrument, but most studies included relatively small cohorts and no reference scores are available. The development of a PedsQL Cancer Module benchmark, based on a large population of pediatric can
The technological evolution and widespread availability of wearables and handheld ECG devices capable of screening for atrial fibrillation (AF), and their promotion directly to consumers, has focused attention of health care professionals and patient organizations on consumer-led AF screening. In this Frontiers review, members of the AF-SCREEN International Collaboration provide a critical apprais
Objectives. To study the in vitro stability of free and complexed forms of prostate specific antigen (PSA) in blood samples in order to establish guidelines for specimen handling, in particular for the clinical utility of the analysis of percentage free PSA. Methods. Blood samples were collected and processed to generate serum, heparin plasma, and EDTA plasma. Three different two-site immunoassays
Primary debulking surgery (PDS) followed by platinum-based postoperative chemotherapy isthe standard of care for advanced ovarian cancer (AOC). Absence of macroscopic residualdisease after debulking surgery is the strongest prognostic factor achieved by surgery. Correctcharacterization of the tumor specimen and tumor spread in combination with patient’scharacteristics such as age, comorbidity, and
Laglotten regleras i ärvdabalken (1958:637) 7 kap. 1 § och fungerar som ett arvsrättsligt skydd till förmån för bröstarvingar. Skyddet aktualiseras i de fall då en avliden valt att testamentera bort all kvarlåtenskap. Bröstarvingar har i dessa fall en lagstadgad rätt till hälften av den dödes arvslott. Laglottsregleringen infördes år 1857, men har som institut funnits betydligt längre inom svensThe statutory share of inheritance is regulated by the inheritance code (1958:637) 7 chap. 1 § and work as a protection for the forced heir to secure its right for inheritance. The protection is activated in those cases where a deceased person has chosen to not give any of the properties left to a forced heir. In these cases, the statutory share of inheritance gives the forced heir the right to a
The terrestrial ecosystem stores up to 2400Gt of carbon in the upper 1m of the soil profile. However, this carbon storage is not stable and is vulnerable to loss. Agricultural soils with continuous heavy management drive a release of this soil carbon to the atmosphere. Recently, the implementation of perennial crops has been suggested as a method to facilitate a greater carbon sequestration. Howev
