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Background: Recently developed buprenorphine depot injections have the potential to reduce risk for diversion and misuse, and to increase adherence with fewer visits for supervised intake. However, it is unclear how patients perceive this new form of medication. The purpose of this study was to explore patients experiences of depot injections and their reasons for continuing, discontinuing, or dec

I denna studie undersöks en vanlig fråga i utvecklingsländer - att informella arbetsrelationer kvarstår när den småskaliga gruvsektorn (ASM) ställs under statlig kontroll. Detta undersöks genom en studie av formaliseringsreformer i Rwandas 3Ts-sektor (tenn, tantal, volfram) för småskalig gruvdrift, som intensifierades från 2010. Forskningen syftar till att förklara den roll som arbetskraft, som båThis study explores a common issue in developing countries – the persistence of informal labour relations when the artisanal and small-scale mining (ASM) sector is brought under state control. It investigates this through a study of formalisation reforms in Rwanda’s 3Ts (tin, tantalum, tungsten) small-scale mining sector, which intensified from 2010. The research aims to explain the role that labo

Background: This study compared levels of physical activity (PA) and sedentary behavior (SB) in adults with and without chronic diseases or multimorbidity, acknowledging sociodemographic factors. Methods: A cross-sectional analysis was conducted with data from 27,890 participants (52% women), aged 50–64, from the Swedish CArdioPulmonary bioImage Study cohort. Over 1500 chronic diseases were includ

Purpose: This study aimed to evaluate the ability of a thigh-worn accelerometer to detect walking during daily life in individuals with Lumbar Spinal Stenosis (LSS). Two hypotheses were made regarding how walking measurements from the accelerometer, a walking test, and an ankle-worn StepWatch would relate in order for the accelerometer to be valid. The hypotheses were: (a) there is no difference b

δ13C data from Tethyan sections provide evidence of profound changes in the carbon cycle during the Lower Triassic. Sections from the Panthalassa realm were investigated to establish whether these variations are also present there. In the Jurassic accretionary wedges in Japan, exotic blocks having a Panthalassan affinity, have been incorporated. The majority of the blocks are pelagic cherts but ra

Understanding how environmental variation influences even cryptic traits is important to clarify the roles of selection and developmental constraints in past evolutionary divergence and to predict future adaptation under environmental change. Female yellow dung flies (Scathophaga stercoraria) typically have three sperm storage compartments (3S), but occasionally four (4S). More spermathecae are th

System Thinking is the mindset of defining and confining a problem and its symptoms as well as a method for communicating system understanding. System Analysis is taking that problem apart to understand its causalities and structural arrangement. System Dynamics is the use of the results of System Analysis in order to reconstruct the system of causalities. Modelling is used for understanding comp

The aim of this study was to evaluate the contribution of insulin processing to the improved meal-related B-cell function previously shown with the DPP-4 inhibitor vildagliptin. Fifty-five patients with type 2 diabetes (56.5 +/- 1.5 years; BMI=29.6 +/- 0.5kg/m(2); FPG = 9.9 +/- 0.2 mmol/l; HbA1c=7.7 +/- 0.1 %) were studied: 29 pateients were treated with vildagliptin and 26 patients with placebo,

OBJECTIVES: To correlate femoral neck Hounsfield units (HUs) measured on a computed tomography (CT) scan to dual-energy x-ray absorptiometry (DEXA) T-scores allowing evaluation of bone mineral density (BMD) over time after lower extremity trauma-related amputation.DESIGN: Retrospective cohort study.SETTING: United States military trauma referral center.PATIENTS: Military combat-related lower extre

Introduction. The introduction of publicly available large language models (LLMs) since 2022 has significantly challenged traditional library and information studies (LIS) core concepts. This paper argues that LIS needs to rethink aspects of its conceptual framework to address the challenges posed by the proliferation of AI-generated content and how this content is produced.Analysis. The study emp

Land use change from agricultural intensification has been highlighted as one of the major drivers of global declines in insects, reducing species diversity and abundance and shifting community composition towards generalist species. However, it remains a challenge to determine how land use change impacts the genetic diversity of species and populations even if this diversity is vital to their lon

OBJECTIVE: Systemic inflammatory autoimmune diseases (SIADs) such as systemic lupus erythematosus (SLE), primary Sjögren disease (pSS), and idiopathic inflammatory myopathies (myositis) are complex conditions characterized by shared circulating autoantibodies and clinical manifestations, including skin rashes, among others. This study was aimed at elucidating the genetics underlying these common f

Purpose: Pancreatic ductal adenocarcinoma (PDAC) can be classified into distinct histological subtypes based on the WHO nomenclature. The aim of this study was to compare the prognosis of conventional PDAC (cPDAC) against the other histological variants at the population level. Methods: The Surveillance, Epidemiology and End Results (SEER) database was used to identify patients with microscopicall

Background: Non-β-hemolytic streptococci (NBHS) cause blood stream infections (BSI) which can be complicated by infective endocarditis (IE). To stratify the risk for IE in NBHS BSI and to guide the use of echocardiography in this condition, two risk stratification systems (RSSs), the HANDOC score (HANDOC), and the Chamat-Hedemand algorithm (CH-A) have been developed.Objectives: To compare the sens

I situationer där vårdnadshavare inte är överens om ett barn ska få psykiatrisk utredning eller behandling finns det en möjlighet för socialnämnden att besluta i en vårdnadshavares ställe enligt 6 kap. 13 a § föräldrabalk (1949:381) (FB). Bestämmelsen aktualiseras exempelvis när vårdnadshavare är oense om huruvida ett barn ska utredas eller medicineras mot ADHD. Syftet med bestämmelsen är att till

Denna uppsats syftar till att undersöka det strukturella problem som uppstår i säkerhetsrådet när rådet hamnar i en rättslig återvändsgränd på grund av ett veto. Uppsatsen utgår från diskussioner kring soft laws påverkan samt användning inom folkrätten och huruvida det kan vara ett användbart instrument för att kringgå sådana rättsliga återvändsgränder. FN-stadgan konstruerades på ett sätt som möjThis essay aims to examine the structural problem that arises in the Security Council when the Council finds itself in a legal impasse due to a veto. The essay is based on discussions on the impact and use of soft law in international law and whether it can be a useful instrument to circumvent such legal impasses. The UN Charter was constructed in a way that allowed for this structural problem bec

Denna uppsats behandlar EU:s nya regler som förändrar kravet på prospekt - ett detaljerat informationsdokument som företag måste publicera när de erbju-der aktier till allmänheten eller noterar dem på en marknadsplats. Prospektet skyddar investerare genom att ge klar information om företaget, aktierna och riskerna, så att de kan fatta välgrundade beslut. Uppsatsen fokuserar på "tröskelvärdet&This essay discusses how the EU's new regulations change the requirement for prospectus - a detailed information document that companies must publish when offering shares to the public or listing them on a marketplace. The prospectus protects investors by providing clear information about the company, the shares, and the risks, enabling them to make well-informed investments. The essay focuses

Abstract: Quantum coherence plays a fundamental role in the study and control of ultrafast dynamics in matter. In the case of photoionization, entanglement of the photoelectron with the ion is a well-known source of decoherence when only one of the particles is measured. Here, we investigate decoherence due to entanglement of the radial and angular degrees of freedom of the photoelectron. We study

OBJECTIVE: To compare experts' perceived usefulness of audit filters from Ghana, Cameroon, WHO and those locally developed; generate context-appropriate audit filters for trauma care in selected hospitals in urban India; and explore characteristics of audit filters that correlate to perceived usefulness.DESIGN: A mixed-methods approach using a multicentre online Delphi technique.SETTING: Two large

We present a statistical mechanics theory of rubber-like elasticity in swollen and unswollen polymer networks characterized by explicitly non-Gaussian distribution functions (Laplace's, Cauchy's, and continuous Poisson's in the exponential limit). An important outcome is the derivation of new families of statistical and mechanical laws, including a discussion of energy functions of strain invarian