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Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330) measured using dual energy X-ray absorptiometry or bioelectrical impedance analysis, adjusted for sex, age, height, and fat mass. Twenty-one si
The problem of designing robust and noise-insensitive PI controllers for pressure-sensor based combustion-timing control was studied through simulation. Different primary reference fuels (PRF) and operating conditions were studied. The simulations were done using a physics-based, control-oriented model with an empirical ignition-delay correlation. It was found that the controllable region, in-betw
A full-scale inside out hollow fibre membrane module was operated in a pilot-scale water treatment plant in Sweden for a period of 12 months from August 2013 to July 2014. Liquid chromatography– organic carbon detection (LC-OCD) chromatogram indicated the membranes could effectively remove 86% of dissolved organic carbon and 92% of humic substances from the feedwater. Routine cleaning-in-place was
The 2017 Global Award for Entrepreneurship Research is given to Hernando de Soto, president of the Institute for Liberty and Democracy (ILD) in Lima, Peru. Over the last 30 years, Hernando de Soto has been a world-leading intellectual engaged in academic and public policy discussions on global development. He has made substantial contributions to our understanding of the informal economy and of th
This paper reports simultaneous detection of ultra violet (UV) absorbance and native UV-excited fluorescence in an electrophoresis microchip using UV transparent integrated waveguides. Absorbance detection enables detection of a wide range of analytes. When exposed to UV light, some compounds also exhibit native fluorescence, which is here detected simultaneously. Calibration curves were measured
[Context and motivation] In market-driven software development it is crucial, but challenging, to find the right balance among competing quality requirements (QR). [Problem] In order to identify the unique challenges associated with the selection, trade-off, and management of quality requirements an interview study is performed. [Results] This paper describes how QR are handled in practice. Data i
Type 1 (T1D) and type 2 (T2D) diabetes share pathophysiological characteristics, yet mechanistic links have remained elusive. T1D results from autoimmune destruction of pancreatic beta cells, whereas beta cell failure in T2D is delayed and progressive. Here we find a new genetic component of diabetes susceptibility in T1D non-obese diabetic (NOD) mice, identifying immune-independent beta cell frag
Background: Current prostate cancer screening guidelines conflict with respect to the age at which to initiate screening. Objective: To evaluate the effect of prostate-specific antigen (PSA) screening versus zero screening, starting at age 50-54 yr, on prostate cancer mortality. Design, setting, and participants: This is a population-based cohort study comparing 3479 men aged 50 yr through 54 yr r
This qualitative study examines how the Israeli occupation affects and interferes with Palestinian intimate relationships in the Occupied Palestinian Territories. The research material consists of semi-structured interviews with female students and graduates conducted during a short period of fieldwork in the West Bank in September 2016. The thesis shows that Israeli mechanisms of control, such as
Den iranska staden Bam drabbades av en kraftig och ödesdiger jordbävning den 26 december 2003 som resulterade i att hela staden ödelades och tiotusentals av stadens invånare omkom. Det faktum att jordbävningen inträffade 05.26 på morgonen i kombination med traditionellt byggda bostadshus med lera som huvudmaterial var de främsta anledningarna till den höga dödssiffran och förstörelsen i staden. Ok
Background: Warehouses serve an important role in many supply chains as they can affect business competitiveness in terms of both costs and customer service. However, the cost of operating a warehouse is often high due to the presence of many non-value adding activities. Lean is a philosophy that can be used to eliminate waste and enable cost reductions in companies. By implementing Lean warehousi
