Filetype
Background: Malignant melanoma is the most lethal form of skin cancer with a variable clinical course even in patients with thin melanomas and localized disease. Despite increasing insights into melanoma biology, no prognostic biomarkers have yet been incorporated into clinical protocols. Reduced expression of the RNA binding motif protein 3 (RBM3) has been shown to correlate with tumour progressi
BACKGROUND: High concentrations of lithium in drinking water were previously discovered in the Argentinean Andes Mountains. Lithium is used worldwide for treatment of bipolar disorder and treatment-resistant depression. One known side effect is altered thyroid function. OBJECTIVES: We assessed associations between exposure to lithium from drinking water and other environmental sources and thyroid
The compact city model emerged as a sustainable response against the dominant trend of urban sprawl. However, the compact city model is not without controversy. Many scholars have questioned the veracity, feasibility and desirability of the compact city through three sets of critiques. Results from the desirability dimension have led to criticism of the model for running counter to the residential
Geofysiska mätmetoder kan tids- och kostnadseffektivt skapa tvådimensionella (2D) och tredimensionella (3D) modeller som avspeglar geologin och som kan användas som ett verktyg för kartläggning av grundvattentillgångar. I denna studie har fyra profiler belägna i den s.k. Vombsänkan i sydöstra Skåne undersökts med galvanisk resistivitetsmätning (ERT) och Transient Elektronmagnetisk Sondering (TEM)Geophysical methods can create 2D- and 3D-models that reflects the geology. These models can be used as a tool for mapping groundwater resources. Four profiles, located in Vombsänkan in southeastern Skåne, have been investigated with Electrical Resistivity Tomography (ERT) and ground-based Transient Electromagnetic Soundings (TEM) as a study of the two methods. The resistivity profiles from the g
BACKGROUND: Postmenopausal hormone therapy (HRT) and oral contraceptive (OC) use have in several studies been reported to be associated with a decreased colorectal cancer (CRC) risk. However, data on the association between HRT and OC and risk of different clinicopathological and molecular subsets of CRC are lacking. The aim of this molecular pathological epidemiology study was therefore to evalua
Popular Abstract in Swedish Mikroorganismer finns överallt! De klarar av att överleva i extrema miljöer, extrema pH, extrema temperaturer och kan motstå strålning och gift i doser som vi inte skulle överleva. Framförallt klarar mikroorganismer av att överleva i en specifik extrem miljö - människan. Hundratals olika mikroorganismer bor på och i oss, i ett antal som långt överskrider vårt eget cellaMicroorganisms are everywhere! They can tolerate many diverse extreme environments, such as the human body. Even though many of us might associate the word microorganism with infections and disease, most are actually either harmless or even beneficial for us. Those commensals often fight off more dangerous bacteria and might also directly benefit their host. The human skin harbors several differen
In my paper I have compared popular science and neutral science regarding language and construction. My task was to find out if there are differences between the language of popular science and that of scientific science. The purpose of my paper is to answer four questions 1.How do the authors present the bogbodies and the mummies in the two categories? 2.What does the popular science imagine th
Article 28 is one of the key Treaty Articles concerning the integration of national markets. But finding the right way to apply Article 28 is far from being easy, as history shows. The ECJ has not been consistent in its case law on Article 28 EC. The main problem in its approach in the application of Article 28 has been the wideness of the Dassonville-formula, which by its wording catches smallest
Due to the globalization with free labour transfer, migrant workers are unavoidably the most targeted group for human trafficking business. Trafficking in persons is a global issue because of its engagement with the international organized crime. Apart from that, as the Protocol on Trafficking in Persons has been in force since 2003, States have turned their attention to the issue and many of them
Cities affected by the impacts of climate change have to find new ways to adapt to the variability in weather patterns, such as heavy rainfalls and storms. The coastal city Malmö, a former industrial city, aims to be carbon neutral by 2020 and provided by 100 percent renewable energies in 2030. However, Malmö is facing many environmental and socio-economic challenges. One of these challenges is to
Den här uppsatsen handlar om nedskräpning, insamling och återvinning av plast på Bali i Indonesien. På grund av osäkra avfallshanteringssystem, brist på kunskap och få incitament för insamling, har plastavfall en tendens att hamna i naturen där det sedan förorenar mark och vatten, och därmed utgör en risk för djurs och människors hälsa. Genom en fallstudie av den vinstdrivande och sociala organisaThis thesis studies plastic littering, collection and recycling on Bali in Indonesia. Due to unsound waste management systems, low awareness and few incentives for collection, plastic waste has the tendency to leak to the environment, where it pollutes land and water, and poses a threat to wildlife and human health. With a case study of the for-profit social enterprise the Plastic Bank that trades
Induction machines have been used in a wide range of applications due to its robustness and its low price. These characteristics make the induction machine a suitable option for industrial and home environments especially for those applications where the required speed is constant and the load does not change drastically. As an alternative to the induction machine, the synchronous machine, particu
Avtalslicensbestämmelserna ger en nyttjare rätt att, på vissa i upphovsrättslagen angivna områden, träffa avtal om användning av upphovsrättsligt skyddade verk med en organisation som företräder ett flertal svenska upphovsmän på området. Genom avtalslicensen får användaren även rätt att nyttja verk av det slag och på de villkor som preciseras i avtalet av upphovsmän som inte är medlemmar av den avThe extended collective licenses grant a user the right to, under provisions that are stated in the Swedish Act on Copyright in Literary and Artistic works, enter agreement about exploitation of works with an organization that represent a substantial number of Swedish authors in the field concerned. Thanks to the extended collective license, the user is granted the right to use works protected by
Phosphoryl transfer plays key roles in signaling, energy transduction, protein synthesis, and maintaining the integrity of the genetic material. On the surface, it would appear to be a simple nucleophile displacement reaction. However, this simplicity is deceptive, as, even in aqueous solution, the low-lying d-orbitals on the phosphorus atom allow for eight distinct mechanistic possibilities, befo
Diffusion-MRI techniques allow the non-invasive investigation of microstructural changes in living tissues. However, a detailed interpretation of the data is complicated by the fact that multiple microscopic environments with varying diffusion properties all contribute to the measured signal. To address this problem, we adapt strategies from solid-state NMR spectroscopy and magnetic resonance of p
Myeloid cells play a central role in atherosclerosis. We investigated the associations between the plasma levels of growth factors and chemokines that regulate myeloid cell homeostasis and function and the risk of first-time acute coronary events in middle-aged persons. Methods and Results-We measured baseline plasma levels of macrophage colony-stimulating factor monocyte chemotactic protein 1; C-
Introduction: In Sierra Leone, West Africa, there are many people with disabilities in need of rehabilitation services after a long civil war. Sierra Leone is among the ten least developed countries in the world and half of the population live under the absolute poverty line with an income less than $1.25 a day. Aim: The aim of this qualitative study was to explore the experiences of prosthetic an
Background: In stage I/II natural killer (NK)/T-cell lymphoma, concurrent chemoradiotherapy (CCRT) had previously been shown to result in superior outcome compared with anthracycline-containing regimens, which have since been considered ineffective. The role of CCRT in comparison with approaches employing nonanthracycline-containing chemotherapy (CT) and sequential radiotherapy (RT) in such patien
Background: Alzheimer's disease (AD) is the most common neurodegenerative disorder. Depositions of amyloid β peptide (Aβ) and tau protein are among the major pathological hallmarks of AD. Aβ and tau burden follows predictable spatial patterns during the progression of AD. Nevertheless, it remains obscure why certain brain regions are more vulnerable than others; to investigate this and dysregulate
Background: The epidemic of Alzheimer's disease (AD) represents a significant challenge for the health care and social service systems of many developed countries. AD affects both patients and family caregivers, on whom the main burden of care falls, putting them at higher risk of stress, anxiety, mortality and lower quality of life. Evidence remains controversial concerning the effectiveness of p
