Search results

Various biological problems such as disease mechanisms, drug development and toxicological studies motivated the introduction of cellular models that today also represent an alternative for reducing the use of animals in controversial medical and pharmaceutical experiments. Cells are complex matrices where several processes occur simultaneously. Because of this, analytical methods with specific p

The question of whether proteins originate from random sequences of amino acids is addressed. A statistical analysis is performed in terms of blocked and random walk values formed by binary hydrophobic assignments of the amino acids along the protein chains. Theoretical expectations of these variables from random distributions of hydrophobicities are compared with those obtained from functional pr

A directly cooled winding in an electrical machine is an appealing solution for a traction application when the electrical machine is operating near peak power for extended periods of time. This directly cooled winding is based on a laminated structure where the power losses in the conducting strips are instantly dissipated by an air-flow between the strips. As an outcome, the hottest component of

The closely related receptor tyrosine kinases c-Kit and Flt3 are mainly expressed in hematopoietic cells and are involved in driving cell proliferation and promoting survival in response to growth factor stimulation. Several gain-of-function mutations of both c-Kit and Flt3 have been found in malignancies like acute myeloid leukemia, gastrointestinal stroma tumors and small cell lung carcinomas, a

Johansson BB. Current trends in stroke rehabilitation. A review with focus on brain plasticity. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2010.01417.x. (c) 2010 John Wiley & Sons A/S. Current understanding of brain plasticity has lead to new approaches in ischemic stroke rehabilitation. Stroke units that combine good medical and nursing care with task-oriented intense training in an environm

Adsorption of uncharged homopolymers in good and theta solvents onto planar surfaces at various chain flexibility and polymer-surface attraction strengths was investigated by using a coarse-grained bead-spring polymer model and simulation techniques. Equilibrium properties of the interfacial systems were obtained from Monte Carlo simulations by monitoring the bead and polymer density profiles, the

Popular Abstract in Swedish Genom att använda marina sedimentkärnor från havbotten kan vi dyka ner i forna tiders hav och förstå hur klimat och havsmiljö har utvecklats över tid. Sedimenten och dess innehåll av olika mikrofossil utgör ett fantastiskt miljöarkiv och ju längre ner i sedimenten vi kommer desto äldre är de vanligtvis. I mitt doktorandprojekt har jag studerat marina sediment från kusteThere is a limited understanding of how the benthic environment within upwelling regions responded to past rapid climatic changes. Within this thesis, a multiproxy approach is applied to two marine sediment cores from two coastal upwelling sites in the low latitude subtropical Atlantic. With a focus on benthic foraminiferal faunal analyses, the response of the benthic environment to rapid climatic

Alpha-synuclein (SNCA) protein aggregation plays a causal role in Parkinson's disease (PD). The SNCA protein modulates neurotransmission via the SNAP receptor (SNARE) complex assembly and presynaptic vesicle trafficking. The striatal presynaptic dopamine deficit is alleviated by treatment with levodopa (l-DOPA), but postsynaptic plastic changes induced by this treatment lead to a development of in

The ammoxidation of propane is commonly regarded as being the future route for producing acrylonitrile, and the Mo-V-Nb-Te-oxide system studied here has thus far been seen as the most promising candidate for achieving this. Yields of up to 62% have been presented very elegantly in the patent literature. A great disadvantage has been, however, that the crystalline quality of the catalyst tends to b

Bacteria and fungi are the main agents in decomposition of soil organic matter. Their activity is determined by the availability and quality of substrate, especially its content of carbon, but also nitrogen and phosphorus. Other environmental factors, which affect the activity of the microbial community in soil, are temperature, moisture and pH. In this thesis the focus was on how temperature and

Popular Abstract in Swedish Den svenska grundskolan har under de senaste åren genomgått och genomgår fortfarande en stark utveckling inom ramen för den allmänna decentraliseringen i samhället. Beslut och ansvar läggs allt längre ner i organisationen. De krav som ställdes på en skolledare tillbaka i tiden var i första hand att han skulle vara administratör och den som bevakade att skolans verk-samThe issues of the study are: How do the assistant principals face the work as school leaders? Which demands of competence do the new school leaders face? Which needs of competence development exist for new school leaders? In the school studied the organization of the management was changed from one principal and one director of studies to one principal and six assistant principals. All of these we

Purpose of this paper The purpose of this paper is to present a comparative case study of the procedures and guiding principles in the packaging selection practice of two international companies. Design/methodology/approach A qualitative case study with an inductive approach was conducted. The data was collected through semi-structured interviews, documentation, and field visits. Findings Th

Previous research has found that weak institutions can hamper investment and alter patterns of trade. However, little is known about the impact of institutional quality on offshoring. This lack of knowledge is surprising, given that offshoring has become an important part of many firms' internationalization strategies. This study uses detailed firm-level data for the 1997-2005 period to examine th

This study investigated a possible mechanism behind employment discrimination. Participants completed a recruitment task where emphasis on cohesion (employees should “fit in”) vs. fairness (everybody should be treated equally) was manipulated by describing the norms of a fictitious company differently. There was a comparatively stronger preference in the cohesion condition for traits and interview

Direct ozone (O-3) injection is a promising flue-gas treatment technology based on oxidation of NO and Hg into soluble species like NO2, NO3, N2O5, oxidized mercury, etc. These product gases are then effectively removed from the flue gases with the wet flue gas desulfurization system for SO2. The kinetics and mixing behaviors of the oxidation process are important phenomena in development of pract

A measurement of elastic deeply virtual Compton scattering gamma*p --> gamma p using e(+) p and e(-) p collision data recorded with the HI detector at HERA is presented. The analysed data sample corresponds to an integrated luminosity of 306 pb(-1), almost equally shared between both beam charges. The cross section is measured as a function of the virtuality Q(2) of the exchanged photon and the ce