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Objectives The aim of this study was to confirm the influence of TNFSF4 polymorphisms on systemic sclerosis (SSc) susceptibility and phenotypic features. Methods A total of 8 European populations of Caucasian ancestry were included, comprising 3014 patients with SSc and 3125 healthy controls. Four genetic variants of TNFSF4 gene promoter (rs1234314, rs844644, rs844648 and rs12039904) were selected

Background: Little is known regarding treatment with cangrelor during percutaneous coronary intervention (PCI) in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Objectives: The aim of this study was to investigate the effects of such cangrelor treatment during PCI in patients with myocardial infarction complicated by cardiogenic shock or cardiac arrest. Met

This study aimed to obtain high-resolution 3D isotropic turbo spin-echo (TSE) wrist MRI acquisitions at 7T, with and without fat suppression, facilitated by compressed-sensing (CS) acceleration. In 16 healthy subjects, fat-suppressed (FS) and nonfat-suppressed (NFS) TSE wrist images were obtained. The protocol consisted of a SENSE-accelerated scan, with an isotropic voxel size of 0.45 mm and acqui

BACKGROUND: Platelet transfusions are frequent in the Intensive Care Unit (ICU), either as prophylaxis against bleeding complications or as treatment for bleeding. The European Society of Intensive Care Medicine guidelines for ICU patients generally recommend not using prophylactic platelet transfusions unless the platelet count falls below 10 × 10 9 cells/L in non-bleeding patients and make no re

Popular summary The fate of non-steroidal anti-inflammatory drugs The knowledge about distribution of drugs between sewage sludge, water phases and water living organisms is vital for predictions of the fate and transport routes of toxic substances to the environment. And the distribution of drugs in the environment can be used as a base for risk assessments and it also can be used to define desir

Executive summary Title: Energy optimization at a chemical industry enterprise Case study - Perstorp AB Authors: Sandra Leksell and Anna Parsdotter Supervisors: Patrick Lauenburg, PhD, Dept. of Energy Sciences, Faculty of Engineering, Lund University and Daniel Hansson, Technical Manager, Perstorp Specialty Chemicals AB Background: The industrial sector in Sweden consumed 152.4 TWh energy in 2010,

We set out to investigate whether the methodologies used in extreme value analysis are applicable in estimating Value at Risk (VaR) for the spot price returns of the European Energy Exchange (EEX). An initial inspection of hourly data reveals a volatile behaviour where returns of extreme proportions occur frequently. Applying the two traditional extreme value theory methods to the data, Block Maxi

Overheating in buildings is becoming a major concern and cause for various health issues. Existing research and previous studies on the issue were examined to acquire relevant information about the definition of overheating, its possible causes, and the heath impacts it could have on human health. The review included data on the current status of thermal comfort and overheating regulations in Swed

OBJECTIVE—To examine the effects of dipeptidyl peptidase-IV (DPP-4) inhibition on meal-related β-cell function and insulin sensitivity over 52 weeks in type 2 diabetes. RESEARCH DESIGN AND METHODS—In a 12-week core study, placebo (n = 51) or vildagliptin (n = 56; 50 mg OD) was added to metformin treatment (1.5–3.0 mg/day). A 40-week extension followed in 71 patients. Meal tests were performed at

Leptin is a key biological marker related to energy balance and development of diabetes and cardiovascular diseases. Its levels are increased in populations with a high degree of the metabolic syndrome. Life history of evolution has, however, largely taken place under the ecological context of hunting and gathering. In this study, we explored whether the first steps of transition to sedentary agri

Background: Metabolic syndrome (MetS) remains a controversial entity. Specific clusters of MetS components - rather than MetS per se - are associated with accelerated arterial ageing and with cardiovascular (CV) events. To investigate whether the distribution of clusters of MetS components differed cross-culturally, we studied 34,821 subjects from 12 cohorts from 10 European countries and one coho

Background: Frontotemporal dementia (FTD) is recognised as a clinically and morphologically heterogeneous group of interrelated neurodegenerative conditions. One of the subtypes within this disease spectrum is the behavioural variant FTD (bvFTD). This is known to be a varied disorder with a mixture of tau-positive and tau-negative underlying pathologies. The other subtypes include semantic dementi

Objective To investigate the possible association of the BANK1 gene with genetic susceptibility to systemic sclerosis (SSc) and its subphenotypes. Methods A large multicentre case-control association study including 2380 patients with SSc and 3270 healthy controls from six independent case-control sets of Caucasian ancestry ( American, Spanish, Dutch, German, Swedish and Italian) was conducted. Th

Looking back at the TEDDY study: lessons and future directions Nature Reviews Endocrinology nature reviews endocrinology https://doi.org/10.1038/s41574-024-01045-0 Review article Check for updates Looking back at the TEDDY study: lessons and future directions Åke Lernmark   1 , Daniel Agardh1, Beena Akolkar2, Patricia Gesualdo   3, William A. Hagopian4, Michael J. Haller   5, Heikki Hyöty6, Suzann

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-04/170_MP303_Lernmark_Nature%20Rev%20Endo_2024.pdf - 2026-05-07

Date Speaker Topic Author ads December 15, 2020 Eero Vaher GAIA EDR3     December 8, 2020 Christian Sahlholdt astronomical databases: miscellaneous; astrometry; stars: distances; Astrophysics - Astrophysics of Galaxies de Jong et al. Benford's law in the Gaia universe November 17, 2020 Thomas Ronnet Planetary Science Deng et al. Early oxidation of the martian crust triggered by impacts November 10

https://www.astro.lu.se/calendar/journal-club/past-speakers-2016-2020 - 2026-05-05

Rutin för chefer med ansvar för anställdas arbetsmiljö På denna sida kan du läsa mer om hur riskbruk och skadligt bruk på arbetsplatsen kan förebyggas. Innehåll på sidan:InledningSystematiskt arbetsmiljöarbeteKunskaper hos anställdaUtbildning och information som riktar sig till anställdaBedöm risker gällande riskbruk och skadligt brukTillbud och olycksfallLäs mer om medberoende och om alkohol i sa

https://www.hr-webben.lu.se/arbetsmiljo/anstalldas-halsa/riskbruk-och-skadligt-bruk/rutin-chefer-med-ansvar-anstalldas-arbetsmiljo/forebygg-riskbruk-och-skadligt-bruk-pa-arbetsplatsen - 2026-05-05

24 to 27 April 2025 The collaboration between INTONAL and IAC is renewed this year, once again hosting IAC’s Acousmonium in the Red Room. First set up fifteen years ago, this unique sound system, now comprising more than 40 speakers, has been continuously refined and improved year after year thanks to the artists who have used it, experimented with it, and proposed innovations to expand its possib

https://www.iac.lu.se/intonal-2025-acousmatic-concerts-iac - 2026-05-05

Allmän civilrätt med juridikdidaktik (JACL01) – distanskurs Det här är kursen för dig som vill lära dig mer om civilrätt! Under kursens gång arbetar du med ämnesdidaktiska seminarier och praktiska övningar. Kursen ger dig en bred förståelse för allmän civilrätt samt hjälper dig att utveckla ett analytiskt och reflekterande förhållningssätt. Anmäl dig för att lära dig mer om juridiken som omger oss

https://www.jur.lu.se/utbildning/utbildning-gymnasielarare/sommarkurser-gymnasielarare/allman-civilratt-med-juridikdidaktik-15-hp - 2026-05-05