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Acute postoperative pain remains a major clinical challenge, affecting both recovery and resource utilisation. Beyond nociceptive input, pain is shaped by cognitive and emotional factors, including patient expectations. This narrative review examines the role of expectations in perioperative pain modulation, framed within predictive coding and Bayesian inference models. These models conceptualise
BACKGROUND: Secondary peritonitis caused by gastrointestinal perforation is associated with significant morbidity and mortality. Effective management includes surgical source control, antibiotic therapy, and intensive resuscitation. The choice between primary abdominal closure (PAC) and vacuum-assisted closure (VAC) in the management of secondary peritonitis remains a subject of debate.METHODS: Th
Swedish contract law is based on the main principle of freedom of contract, which means that a contract is built on a voluntary agreement of both parties. There are exceptions from the principle of freedom of contract. In some instances a party is obliged to contract (kontraheringsplikt), which also is the subject for this paper. Kontraheringsplikt can be described as an obligation for one of the
In 2014 during an organisational restructuring of Sony Electronics in Lund, an ongoing inhouse project to develop a resource management software was rushed to completion. The software had at the time been in active development by a team of software engineers for over a year but was quickly brought to completion to meet the new directives. Without clear product ownership and review, the softwa
Popular Abstract in Swedish Sexuella övergrepp väcker starka känslor hos oss. Ibland tycks känslorna bli så svåra att vi försöker utestänga den plågsamma verkligheten genom att "blunda" för faktum. För att studera hur människor handskas med förekomsten av ett sexuellt övergrepp på ett barn i en bild, framställdes en bild, som avsåg att visa ett sådant övergrepp. Bilden visades för ett stort antal This investigation comprises five studies of factors determining adults' interpretations of a picture (Threat), drawn to represent sexual abuse of a child. The sexes of the two persons in the picture were on purpose drawn ambiguously. In Study I, the Threat picture was interpreted by 515 undergraduates in three experiments, all resulting in the same four interpretation categories, and similar freq
Popular Abstract in Swedish BLY I BLOD. ICP-MS-studier av bly i plasma, blod och erythrocyt-proteiner De flesta studier som har gjorts av blys giftighet är grundade på blyhalten i blod, och man vet idag mycket om vilka halter som är förknippade med olika skador. Cirka 99% av blyet i blod finns i de röda blodkropparna, medan plasma vanligen innehåller mindre än 1%. Man har länge trott att anledninAn inductively coupled plasma mass spectrometry (ICP-MS) method for the determination of lead in blood plasma has been developed. The detection limit was below 0.1 microgram/liter, and the precision 5%. There was no significant difference between levels in plasma and serum. Studies of individuals with varying lead exposure showed that in the general population the plasma concentrations were less t
Despite the egalitarianism that informs French civic culture, the socio-economic marginalization of citizens of non-European origin, mostly from North African countries, provide empirical evidence that challenges the French Republican ideal of integration. Such marginalization needs to be reconciled especially within the cultural realm. In this article, we look at French newspapers’ coverage of th
Background: L1 is an important primary rRNA-binding protein, as well as a translational repressor that binds mRNA. It was shown that L1 proteins from some bacteria and archaea are functionally interchangeable within the ribosome and in the repression of translation. The crystal structure of bacterial L1 from Thermus thermophilus (TthL1) has previously been determined. Results: We report here the
We evaluated clinical significance of serum alpha-fetoprotein (AFP)-IgM immune complexes, in comparison with free AFP, on the diagnosis of primary hepatocellular carcinoma (HCC). Serum levels of AFP-IgM immune complexes and free AFP were determined by the ELISA method and electrochemiluminescence, respectively, in 103 healthy controls, 74 patients suffering from primary HCC, 27 patients suffering
Structural design is today concerned with single component performance where each limit state is related to a single mode of failure of a single component. Further, in limit state codes the strength variables are related to a deterministic value (usually the 5-percentile). However, in a structure with a number of elements, two different effects (called system effects) can be found: The probabilist
Infantile malignant osteopetrosis (IMO) is a fatal disease caused by lack of functional osteoclasts, and the only available treatment is hematopoietic stem cell (HSC) transplantation. In the majority of patients, the TCIRG1 gene, coding for a subunit of a proton pump essential for bone resorption, is mutated. Oc/oc mice have a deletion in the homologue gene (tcirg 1) and die at 3 to 4 weeks, but c
Many decisions in drug development and medical practice are based on measuring blood concentrations of endogenous and exogenous molecules. Yet most biochemical and pharmacological events take place in the tissues. Also, most drugs with few notable exceptions exert their effects not within the bloodstream, but in defined target tissues into which drugs have to distribute from the central compartmen
In the present work the genetically modified Trichoderma reesei strain QM9414 was used to produce full-length Ce17B (endoglucanase I, EGI) under the control of the constitutive Aspergillus nidulans gpdA promoter in the presence of glucose. However, the full-length Ce17B enzyme was found to be truncated to lower molecular weight components in the culture broth. Truncation of recombinant proteins pr
The compound eye of the cricket Gryllus bimaculatus contains a specialized dorsal rim area (DRA) populated by distinct blue-sensitive photoreceptors responsible for perception of polarized light. The rest of the eye is dominated by green-sensitive photoreceptors. Using patch clamp we studied dissociated ommatidia of nocturnal adults and diurnal eight-instar nymphs with the goals (1) of characteriz
This is the first report of the Twin Mom Study, an investigation. of three hypotheses concerning influences on maternal adjustment. These hypotheses concern the role of the marital and parent-child relationships in mediating genetic influences on maternal adjustment and on the importance of the mothers' marital partners as a specifiable source of influences on their adjustment not shared with thei
Free sodium metal clusters have been studied by probing the Na 2p core level using x-ray photoelectron spectroscopy (XPS) and Auger electron spectroscopy (AES). The development of electronic structure with size has been studied and discussed in comparison with the atom, dimer, and solid. Information on cluster metallic properties, size, and temperature has been deduced from the XPS measurements. F
Popular Abstract in Swedish Blodet innehåller några av de mest grundläggande komponenterna för mänskligt liv. Med hjälp av hjärtats pumpkraft transporterar röda blodkroppar ut syre från lungorna till de mest avlägsna delarna av kroppen via gradvis tunnare blodkärl. Livshotande blödningar stoppas via blodplättarnas koagulerande förmåga och läkande egenskaper, medan de vita blodkropparna bekämpar inHematopoietic stem cells (HSCs) are defined by their capacity to self-renew and differentiate into all hematopoietic cell lineages. Postnatally, HSCs reside predominantly in the bone marrow and are relatively rare, but important cells because of their therapeutic potential in bone marrow transplantation protocols and in their involvement in the origin of certain leukemias. To study how various gen
Using Monte Carlo simulation of 99Tcm single-photon-emission computed tomography (SPECT), we investigate the effects of tissue-background activity, tumour location, patient size, uncertainty of energy windows, and definition of tumour region on the accuracy of quantification. The dual-energy-window method of correction for Compton scattering is employed and the multiplier which yields correct acti
