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Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology
A central question in Alzheimer's disease concerns the mechanism by which β-amyloid contributes to neuropathology, and in particular whether intracellular versus extracellular β-amyloid plays a critical role. Alzheimer transgenic mouse studies demonstrate brain dysfunction, as β-amyloid levels rise, months before the appearance of β-amyloid plaques. We have now used immunoelectron microscopy to de
RE:WATERFRONT : A sustainable architectural approach
RE:WATERFRONT evaluates theories and results from an interdisciplinary design experience with focus on urban architecture in sustainability discourse. Taking the design teaching of “RE:WATERFRONT: Post-industrial harbor transformation at Frihamnen in Gothenburg, Sweden” as a case study, this book intends to tackle the theme of re-development in urban voids. The aim is to introduce a methodological
Finding Gender at the Intersection of Family and Field : Family Presences in Sweden
Gender influences how researchers engage with the field (Porter & Schänzel, 2018). Departing from this proposition, this chapter offers reflections on gender from masculine vantages in the context of a qualitative research project investigating tourism enterprising in southern Sweden. Tourism enterprising is an important aspect of tourism development. Focusing on personal experiences associate
With increasing age at tumor diagnosis in familial cancer: Cancer is limited to fewer organs
Hereditary cancer that has monogenic inheritance affects every tenth patient, on average, who is diagnosed with cancer, and it has been suggested, based on twin studies, that approximately 30% of all cancer patients have a genetic predisposition to developing cancer. In this article, the author posited that familial syndromes become more organ specific with increasing age at tumor presentation to
Mitotic activity and survival in advanced non-Hodgkin's lymphoma of unfavourable histology
Juxtaposed narrative : The dilemma of cultural memory on display in George Town’s street art
Street art is a ubiquitous visual landmark in contemporary George Town, the capital city of Penang state in Malaysia. Both private commissioned and state-sanctioned types of street art are the new significant cultural identification of this World Heritage Site city as inscribed by UNESCO in 2008. Street art in this multicultural city becomes the articulated media that deals with the notion of cult
Catch Me if You Can : Streptococcus pyogenes Complement Evasion Strategies
The human host has evolved elaborate protection mechanisms to prevent infection from the billions of microorganisms to which it host is exposed and is home. One of these systems, complement, is an evolutionary ancient arm of innate immunity essential for combatting bacterial infection. Complement permits the efficient labelling of bacteria with opsonins, supports phagocytosis, and facilitates phag
Wild African Drosophila melanogaster are seasonal specialists on marula fruits
Although the vinegar fly Drosophila melanogaster isarguably the most studied organism on the planet,fundamental aspects of this species’ natural ecologyhave remained enigmatic [1]. We have here investigateda wild population of D. melanogaster from amopane forest in Zimbabwe. We find that these fliesare closely associated with marula fruit (Sclerocaryabirrea) and propose that this seasonally abunda
Results of the COVID-19 mental health international for the health professionals (COMET-HP) study: depression, suicidal tendencies and conspiracism
Introduction: The current study aimed to investigate the rates of anxiety, clinical depression, and suicidality and their changes in health professionals during the COVID-19 outbreak. Materials and methods: The data came from the larger COMET-G study. The study sample includes 12,792 health professionals from 40 countries (62.40% women aged 39.76 ± 11.70; 36.81% men aged 35.91 ± 11.00 and 0.78% no
The effect of natural biomolecules on yttrium oxide nanoparticles from a Daphnia magna survival rate perspective
The attention to rare earth oxide nanoparticles (NPs), including yttrium oxide (Y2O3), has increased in many fields due to their unique structural characteristics and functional properties. The aim of our study was to investigate the mechanisms by which bio-corona formation on Y2O3 NPs affects their environmental fate and toxicity. The Y2O3 NPs induced toxicity to freshwater filter feeder Daphnia
Modelling natural pest control across the world’s agroecosystems – an archetype approach
Control of crop pests by shifting host plant availability and natural enemy activity at landscape scales has great potential to enhance the sustainability of agriculture. However, mainstreaming natural pest control requires improved understanding of how its benefits can be realized across a variety of agroecologies. Empirical studies suggest significant but highly variable responses of natural pes
Making in turbulent times:new insights into late 18th-and early 19th-century ceramic crafts and connectivity in the Magaliesberg region
Among Simon Hall's influential contributions to historical archaeology are two research agendas: The need to focus attention on lower scalar levels of analysis, and broadening the concept of ceramic style to include less visible technological qualities. The latter is of particular importance to the stylistically bland and less decorated assemblages from the 18th and 19th centuries. Combining and d
Storage Assignment using Nested Annealing and Hamming Distances
The assignment of products to storage locations significantly impacts the efficiency of warehouse operations. We propose a multi-phase optimizer for a Storage Location Assignment Problem (SLAP) where solution quality is based on a distance estimate of future-forecasted order picking. Candidate assignments are first sampled using a Markov Chain accept/reject method. Future-forecasted pick-rounds ar
The value of street art : on the commodity status of artworks removed from the street
Localization of an RF source inside the Human body for Wireless Capsule Endoscopy
This paper presents a method based on the phase dierence of arrival and the non-linear least square estimation to lo- calize a radio-frequency (RF) source, e.g a wireless capsule endoscope, inside the human body. The phase dierence of arrival at multiple frequencies of a signal is used to estimate the distance of the source to a receiver. The linear least square estimation is used to estimate the
Yeasts as cellular factories: Saccharomyces cerevisiae strains with improved inhibitor-tolerance to furaldehydes via a mutant alcohol dehydrogenase- and- Human ameloblastin production in Pichia pastoris
Several yeast species, usually engineered by humans in order to produce compounds of biotechnological interests, are currently used as cellular factories. This thesis presents two main themes. In the first, Saccharomyces cerevisiae is used for bio-ethanol production from lignocellulose hydrolysates and in the second Pichia pastoris is used for the heterologous expression of human ameloblastin. Th
Efficacy of Methotrexate in the Treatment of Psoriatic Arthritis: A Critical Literature Review
Msfm01 medicinsk stralningsfysik - grundkurs 2020-05-11
1 HT2018 – VT2019 Kursanalys MSFM01 Medicinsk strålningsfysik - grundkurs MSFM01: Joniserande strålning: produktion, växelverkan, detektion Produktion Martin Bech Analys finns ej för denna delkurs Växelverkan Ronnie Wirestam Undervisningsform och examination Kursen innehåller 21 föreläsningstimmar (laddade partiklar, fotoner, neutroner) under terminens första veckor med en och samma föreläsare (RW
https://www.msf.lu.se/sites/msf.lu.se/files/msfm01_medicinsk_stralningsfysik_-_grundkurs_2020-05-11.pdf - 2026-06-07
Msfm21 medicinsk stralningsfysik - sjukhusfysik 2019-01-17
1 HT2017 – VT2018 Kursanalys MSFM21 Medicinsk strålningsfysik - sjukhusfysik MSFM21: Bildbehandling och dess matematiska metoder Katarina Sjögreen Gleisner Undervisningsform och examination Som ett resultat av att en kursvecka lades till HT 16 är den totala kurstiden nu 7 veckor. Föreläsningarna på kursen ligger i huvudsak fördelade över kursens första tre veckor. Dessa varvas med programmeringsöv
https://www.msf.lu.se/sites/msf.lu.se/files/msfm21_medicinsk_stralningsfysik_-_sjukhusfysik_2019-01-17.pdf - 2026-06-07
