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Heat processing and storage of a berry-based beverage and its influence on polyphenolic compounds – a preparatory analysis of a study product for a clinical trial

Research suggests that polyphenols, such as anthocyanins, that are found in considerable amounts in many types of berries, contributes with a positive effect on human cognition. However, clinical trials are warranted to support these findings. Preparation for such a trial includes developing a berry-rich study product and a corresponding reference beverage. Phenolic compounds are highly unstable a

Surgical outcomes for perforated peptic ulcer: A prospective case series at an academic hospital in Monrovia, Liberia

Introduction The incidence of perforated peptic ulcer remains high in low and middle-income countries. Mortality can be significant, and early surgical management with careful evaluation of pre-operative risk factors is essential. The purpose of this study was to describe the clinical outcomes of surgical treatment for perforated peptic ulcer disease in Liberia and to explore risk factors for adve

Miniaturised and Quantitative Techniques Targeting Prostate Cancer

The prostate-specific antigen (PSA) test used in the clinic today has been subjected to suspicions regarding specificity and sensitivity, since cases of benign prostatic hyperplasia or prostatitis are hard to distinguish from those with prostate cancer. This thesis is based upon five original papers describing efforts to develop antibody microarrays enabling improved diagnostic prostate cancer ana

The influence of ageing on the salt-frost resistance of concrete

Popular Abstract in Swedish Jämte korrosionsangrepp är skador på grund av saltfrostangrepp den vanligaste skadetypen hos betongkonstruktioner som utsätts för miljöer med fukt, salt och frost. Exempel på sådana miljöer är marina miljöer och tösaltade vägmiljöer. Betongens saltfrostbeständighet bestäms till stor del av betongsammansättningen, främst av förhållandet mellan mängden vatten och cement oAbstract This thesis presents the results of an investigation of the influence of ageing on the salt-frost resistance of concrete. The ageing mechanisms investigated were hydration, drying and carbonation. Specimens of ‘micro’-concrete, either with OPC alone as the binder or with silica or slag as part of the binder, were freeze/thaw tested at different ages after casting. Prior to testing, the sp

Aortic valve calcification across stages of dysglycemia in middle-aged individuals from the general population

Background: Aortic valve calcification (AVC) is an underlying pathophysiological mechanism in aortic stenosis, which shares many risk factors with diabetes. However, the association between dysglycemia and early stages of AVC remains unclear. The aim was to examine the associations between stages of dysglycemia and signs of AVC among middle-aged individuals from the general population. Methods: Th

Pediatric Heart Transplantation within the Scandiatransplant Region - A Multinational Observational Study Spanning 38 years

BACKGROUND: Thirty-eight years of pediatric heart transplantation (pHTx) within the Scandiatransplant organization were analyzed to describe volume trends, regional prevalence, underlying etiologies and outcomes following listing and pHTx.METHODS: Children <18 years listed for pHTx from January 1st 1986 to December 31st 2023 were identified in the Scandiatransplant registry. The cohort was split i

Iron insight : exploring dietary patterns and iron deficiency among teenage girls in Sweden

PURPOSE: This observational study examined the relationship between self-reported dietary patterns-omnivore, pescatarian, vegetarian, and vegan-and iron status among Swedish teenage girls. Additionally, we compared the consumption of various food groups in relation to iron status.METHODS: Data were collected from 475 female high school students in Malmö and Lund, Sweden, using questionnaires on di

Severe-Extensive Coronary Atherosclerosis in Low-Risk Individuals and Absence of Coronary Atherosclerosis in High-Risk Individuals : The SCAPIS Extremes Project

AIM: Factors associated with unexpected absence or presence of coronary atherosclerosis in individuals at high/low estimated cardiovascular (CV) risk are largely unexplored. We assessed two extreme phenotypes: 1) no coronary atherosclerosis despite very high CV risk; and 2) severe-extensive coronary atherosclerosis despite low CV risk.METHODS: A multicenter, cross-sectional nationwide, population-

Gaia Data Release 2 : The celestial reference frame (Gaia -CRF2)

Context. The second release of Gaia data (Gaia DR2) contains the astrometric parameters for more than half a million quasars. This set defines a kinematically non-rotating reference frame in the optical domain. A subset of these quasars have accurate VLBI positions that allow the axes of the reference frame to be aligned with the International Celestial Reference System (ICRF) radio frame. Aims. W

Production time analysis at a ring mill

Ovako Ajax me, in York, South Carolina, USA manufactures seamless steel rings. The rings are made from blocks, which are heated, pressed, punched and then rolled to desired size and shape. Due to tougher competition on the seamless steel ring market, it is necessary to know the total production time for an order of specific rings, in order to be able to price the rings correctly and plan the prod

Prevalence of angina pectoris and association with coronary atherosclerosis in a general population

Objective To assess the contemporary prevalence of, and factors associated with angina pectoris symptoms, and to examine the relationship to coronary atherosclerosis in a middle-aged, general population. Methods Data were based on the Swedish CArdioPulmonary bioImage Study (SCAPIS), in which 30 154 individuals were randomly recruited from the general population between 2013 and 2018. Participants

Assessing the Costs of Neuropsychiatric Disease in the Systemic Lupus International Collaborating Clinics Cohort Using Multistate Modeling

Objective: To estimate direct and indirect costs associated with neuropsychiatric (NP) events in the Systemic Lupus International Collaborating Clinics inception cohort. Methods: NP events were documented annually using American College of Rheumatology definitions for NP events and attributed to systemic lupus erythematosus (SLE) or non-SLE causes. Patients were stratified into 1 of 3 NP states (n

A dose planning study for cardiac and lung dose sparing techniques in left breast cancer radiotherapy : Can free breathing helical tomotherapy be considered as an alternative for deep inspiration breath hold?

Purpose: To investigate the possibility to be able to offer left sided breast cancer patients, not suitable for DIBH, an organ at risk saving treatment. Materials and Methods: Twenty patients receiving radiotherapy for left breast cancer in DIBH were enrolled in the study. Planning CT scans were acquired in the same supine treatment position in FB and DIBH. 3DCRT_DIBH plans were designed and optim

Association of metformin use and survival in patients with cutaneous melanoma and diabetes

BACKGROUND: Metformin use has been associated with improved survival in patients with different types of cancer, but research regarding the effect of metformin on cutaneous melanoma (CM) survival is sparse and inconclusive.OBJECTIVES: To investigate the association between metformin use and survival among patients with CM and diabetes.METHODS: All adult patients with a primary invasive CM between

Subject-specific literacy in Physical Education and Health : the case of Sweden

The overall aim of this paper is to introduce a new way of analysing and understanding the framing and potential of Physical Education and Health (PEH) practice. Focusing on subject-specific literacy, which is defined as an abstract and generalising language, containing words and concepts typical for a specific subject [Nestlog, B. E. (2019). Ämnesspråk – en fråga om innehåll, röster och strukture

Delayed and altered post-fire recovery pathways of Mediterranean shrubland under 20-year drought manipulation

Increasing water deficits and severe droughts are expected to alter the dynamics of vegetation post-disturbance recovery by decreasing new recruitment and limiting growth in semi-arid Mediterranean ecosystems in future. However, which vegetation metrics will be shifted and how they respond over time are not clear, and the experimental evidence is still limited. Here we assessed the impacts of a lo

Utilization of psychiatric services prior to suicide- a retrospective comparison of users with and without previous suicide attempts

INTRODUCTION: The aim was to investigate psychiatric health care utilization two years before death by suicide among individuals with previous suicide attempts (PSA) compared with those without (NSA).METHOD: A retrospective population-based cohort study was conducted including 484 individuals who died by suicide in Sweden in 2015 and were in contact with psychiatric services within the two years p

Causes of nephrotic syndrome in Sweden: The relevance of clinical presentation and demographics

Background: Many pathological processes can disrupt the integrity of the glomerular capillary wall and cause a massive leakage of protein, resulting in nephrotic syndrome (NS). Clinical parameters such as age, sex, renal function, presence of diabetes, and how NS is defined influence the spectrum of underlying diseases. In this study, we examine how these parameters interact.Methods: Age, sex, hem

The risk for celiac disease after Covid-19 infection

Background: Celiac disease (CD) is an autoimmune disease leading to gastrointestinal symptoms and mineral deficiencies. The pathogenetic mechanisms, besides the clear HLA association, are elusive. Among environmental factors infections have been proposed. Covid-19 infection results in a systemic inflammatory response that often also involves the gastrointestinal tract. The aim of the present study

Distribution of type 2 biomarkers and association with severity, clinical characteristics and comorbidities in the BREATHE real-life asthma population

Background Type 2 (T2) high asthma is recognised as a heterogenous entity consisting of several endotypes; however, the prevalence and distribution of the T2 biomarkers in the general asthma population, across asthma severity, and across compartments is largely unknown. The objective of the present study was to describe expression and overlaps of airway and systemic T2 biomarkers in a clinically r