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Immune cells of the tumor microenvironment are central but erratic targets for immunotherapy. The aim of this study was to characterize novel patterns of immune cell infiltration in non-small cell lung cancer (NSCLC) in relation to its molecular and clinicopathologic characteristics. Lymphocytes (CD3+, CD4+, CD8+, CD20+, FOXP3+, CD45RO+), macrophages (CD163+), plasma cells (CD138+), NK cells (NKp4

PURPOSE: Tamoxifen prevents breast cancer in high-risk women and reduces mortality in the adjuvant setting. Mammographic density change is a proxy for tamoxifen therapy response. We tested whether lower doses of tamoxifen were noninferior to reduce mammographic density and associated with fewer symptoms.PATIENTS AND METHODS: Women, 40-74 years of age, participating in the Swedish mammography scree

Background: Quantitative magnetic resonance imaging (MRI), e.g. relaxation parameter mapping, may be sensitive to structural and compositional tissue changes, and could potentially be used to non-invasively detect and monitor early meniscus degeneration related to knee osteoarthritis. Objective: To investigate MR relaxation times as potential biomarkers for meniscus degeneration through comparison

BACKGROUND AND OBJECTIVES: Several pathologic processes might contribute to the degeneration of the cholinergic system in aging. We aimed to determine the contribution of amyloid, tau, and cerebrovascular biomarkers toward the degeneration of cholinergic white matter (WM) projections in cognitively unimpaired individuals. METHODS: The contribution of amyloid and tau pathology was assessed through

Course: FEKN90, Degree project for Master of Science in Business and Economics (30 ECTS) Authors: Petrea Godderidge, Nicole Johansson and Lina Larsson Supervisor: Annette Cerne Key words: Generation Y, store loyalty, private labels, grocery retailer Purpose: The purpose of this thesis is to investigate what impact private labels, in relation to other store loyalty driving factors within the

Citizenship regimes in Western Europe are changing. On the one hand, over the past 30 years, citizenship has been liberalized. On the other, in particular over the past ten years, access to citizenship through naturalization has become restricted in most Western European states. This development has been intertwined with public discourses on ‘integration’ of those Europeans who once migrated to th

KOMPLEXA VILLKOR FÖR SJUKHUSLEDNING RESEARCH IN SERVICE STUDIES Working paper No 9, March 2012 The Department of Service Management Campus Helsingborg | Lund University Skrivet för Lodin, H. & Nordgren, L. (red) (2013), Service i ett hälsoperspektiv (Lund: Studentlitteratur) 1 Komplexa villkor för sjukhusledning Skrivet för Lodin, H. & Nordgren, L. (red) (2013), Service i ett hälsoperspektiv (Lund

https://www.ses.lu.se/sites/ses.lu.se/files/wp_9_2012.pdf - 2026-05-19

Background Obesity is increasing among patients with inflammatory bowel disease, but bariatric surgery has been rare in this group owing to concerns about worsening the inflammatory bowel disease. The aim of the study was to evaluate inflammatory bowel disease-related outcomes following bariatric surgery. Methods Nationwide cohort of all adult patients in Sweden between 2007 and 2020 with obesity

Introduction: Carbon monoxide (CO) is a leading cause of environmental poisoning in the United States with substantial mortality and morbidity. The mechanism of CO poisoning is complex and includes hypoxia, inflammation, and mitochondrial dysfunction. Currently both biomarkers and therapies for CO poisoning are limited and require new approaches. Methods: Rats (~ 300 g) were divided into four grou

Rationale, Aims and Objectives: Colonoscopy, though common, can be uncomfortable, necessitating routine assessment of patient experience per European guidelines. Positive patient experiences are crucial as they influence willingness for repeat procedures. Patient-reported experience measures (PREMs) effectively capture patient perspectives through surveys, empowering patients to influence healthca

Background and Aims The prognosis of adult-onset type 1 diabetes (T1D) and prognostic factors are sparsely investigated. This study assessed mortality, major adverse cardiovascular events (MACE), and prognostic factors in adult-onset T1D, particularly focusing on those diagnosed at age ≥40. Methods Participants were people diagnosed with adult-onset T1D (n = 10 184) or type 2 diabetes (T2D, n = 37

Ibrutinib was approved for relapsed/refractory (R/R) mantle cell lymphoma (MCL) based on high response rates in clinical trials, but it is unclear how effective ibrutinib is in the real-world setting. This study provides population-based response rates and survival estimates and characterization of prognostic indicators and adverse events (AEs) to ibrutinib for patients with R/R MCL. All patients

Subject motion and eddy-current distortions represent significant challenges in diffusion MRI, particularly for clinical protocols utilizing "half-sphere" sampling. While the current gold standard, FSL’s eddy, employs Gaussian Process (GP) predictions to correct these artifacts, its performance can degrade under specific acquisition constraints, most notably when sampling lacks antipodal

We report the discovery of two warm exoplanets orbiting the cool binary system TOI-2267, composed of the M5 (TOI-2267A) and M6 (TOI-2267B) stars, whose angular separation is 0.384 arcsec, corresponding to a projected distance of only about 8 au at 22 pc from the Solar System. To confirm the planetary nature of these objects, we combined photometry from the Transiting Exoplanet Survey Satellite (TE

The purpose of this study was to characterize the emissions of a large number of chemical compounds emitted from birch wood combustion in a wood stove. Birch wood is widely used as fuel in Swedish household appliances. The fuel load was held constant during six experiments. Particles < 2.5 mum diameter were collected and the size distribution of the particles was measured. The results were compare

Publications Archive - Page 24 of 43 - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Pro

https://rwi.lu.se/publications/page/24/ - 2026-05-19

BACKGROUND: To reduce the costs of maintaining a poliovirus immunization base in low-income areas, we assessed the extent of priming immune responses after the administration of inactivated poliovirus vaccine (IPV).METHODS: We compared the immunogenicity and reactogenicity of a fractional dose of IPV (one fifth of a full dose) administered intradermally with a full dose administered intramuscularl

For historical reasons, Swedish railways use 15 kV/16? Hz overhead contact lines for train traction, while the most common standard worldwide is 25 kV/50-60 Hz. This leads to higher investment costs for railway conversions and expansions, and to greater energy losses in the distribution of electricity to the trains. Yet to get away from these drawbacks by investing in a 25 kV/50 Hz overhead contac

Heterogena katalysatorer för användning i bränslecellssystem har undersökts baserat på aktiv fas och tillverkningsmetoder för granulat- och monolitkatalysatorer. Katalysatorerna tillverkades genom att använda θ – aluminiumoxid som bärare, dopad med lantan och cerium, där den aktiva fasen bestod av ädelmetall X och nickel i varierande halter. Analys gjordes genom att låta en blandning av vattenångaHeterogeneous catalysts to be used in a pre-reformer for fuel cell systems have been investigated based on active phase composition and catalyst preparation methods for granulate and monolithic catalysts. The catalysts were manufactured using θ – aluminum oxide as carrier, promoted with lanthanum and cerium, with active phases consisting of noble metal X and nickel in various concentrations. Analy

Sandvik Rock Processing in Svedala is a business area within the Sandvik Group who manufactures crushers and spare parts. A new production plant, Greenfield, will be completed in 2013 and as part of the change the company makes in connection with the new plant, there is a desire to revise and optimize the order quantities in the production. There are several models for lot sizing. Economic Order Q