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Thrombotic disease in systemic lupus erythematosus is associated with a maintained systemic platelet activation

Patients with systemic lupus erythematosus (SLE) have an increased risk of thrombosis. Platelet-induced extracellular phosphorylation of plasma proteins suggests that this is due to persistent activation of the platelets. We examined 30 SLE patients (15 with thrombotic disease), 18 non-SLE patients with deep vein thrombosis (DVT) and 50 healthy controls by analysing beta-thromboglobulin, activated

Fire properties of borated polyethylene

This work has been made as a thesis for a BSc degree in Fire Protection Engineering at Lund University. The work has been supported and funded by ESS AB, European Spallation Source, in Lund. ESS AB is a publicly held company, owned by Sweden and Denmark as host countries. These host countries, together with at least 17 other European countries, will build and establish a multidisciplinary research

Symptoms, problems and quality of life in patients newly diagnosed with oesophageal and gastric cancer - a comparative study of treatment strategy

BACKGROUND: Patients with oesophageal and gastric cancer have a low likelihood of being cured and suffer from a broad spectrum of symptoms and problems that negatively affect their quality-of-life (QOL). Although the majority (67-75%) of patients at the time of diagnosis suffer from an incurable disease, research has primarily focused on the pre- and postoperative phase among patients treated with

Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

Background: Oral contraceptive use has been associated with an increase in the risk of breast cancer in young women. We examined whether this association is seen in women at high risk of breast cancer because they carry a mutation in one of two breast cancer susceptibility genes, BRCA1 and BRCA2. Methods: We performed a matched case-control study on 1311 pairs of women with known deleterious BRCA1

Antiretroviral therapy non-adherence among children living with HIV in Dire Dawa, Eastern Ethiopia : a case-control study

Background: In 2018, nearly 90% of the global children living with human immunodeficiency virus (HIV) were in sub-Saharan Africa (SSA). Compared to the adult population, antiretroviral therapy (ART) coverage among children was limited. However, adherence remained a problem among children though they had limited access to ART. This study was conducted to identify the risk factors of non-adher

Nationwide observational study of incidence, management and outcome of spontaneous coronary artery dissection : a report from the Swedish Coronary Angiography and Angioplasty register

Objectives The aim of this study was to conduct a nationwide all comer description of incidence, contemporary management and outcome in Swedish spontaneous coronary artery dissection (SCAD) patients. The incidence of SCAD as well as the management and outcome of these patients is not well described. Design A nationwide observational study. Participants and setting All patients with SCAD registered

Acetylcholine release in the rat hippocampus as studied by microdialysis is dependent on axonal impulse flow and increases during behavioural activation

Changes in extracellular levels of acetylcholine and choline in the hippocampal formation were measured using intracerebral microdialysis coupled to high performance liquid chromatography with post-column enzyme reaction and electrochemical detection. Various pharmacological and physiological manipulations were applied to awake unrestrained normal rats and rats subjected to a cholinergic denervati

Empowering students and helping them experience success (using SI-PASS)

SI-PASS is an academic assistance program that provides help for students in “difficult” courses, often introductory courses for first-year students. The idea behind SI is that learning a subject is enhanced by an exchange of thoughts and ideas between students. The goal is to make the students become active and independent learners that sees peers as a learning resource. SI-PASS is connected to a

Iliac Branch Devices in the Repair of Ruptured Aorto-iliac Aneurysms : A Multicenter Study

PURPOSE: To evaluate the outcomes of preserving the internal iliac artery (IIA) with iliac branched devices (IBDs) during acute endovascular repair of ruptured aortoiliac aneurysms.MATERIAL AND METHODS: This is a multicenter retrospective review of all consecutive patients undergoing acute endovascular repair of ruptured aortoiliac aneurysm with an IBD at 8 aortic centers between December 2012 and

Are Danish doctors comfortable teaching in English?

BackgroundFrom 2012–2015, the Departments of Obstetrics and Gynecology and of Pediatrics at the University of Copenhagen conducted a project, “Internationalization at Home ”, offering clinical teaching in English. The project allowed international students to work with Danish speaking students in a clinical setting. Using semi-quantitative questionnaires to 89 clinicians about use of English and n

Semi-Autonomous Weapon Systems in International Humanitarian Law

Syftet med mitt examensarbete är att undersöka i detalj hur gällande folkrätt förhåller sig till autonoma vapensystem. Bakgrunden till detta projekt är att internationell humanitär rätt förutsätter att aktörerna i kriget, soldater och officerare är människor. Krigföring har dock förändrats i allt högre grad sedan de första Genèvekonventionerna skrevs i augusti 1949. Krig kämpas numera med maskinerThe purpose of my Master Thesis is to examine, in detail, how current international law relates to autonomous weapon systems. The background for this project is that the requirement of current international humanitarian law presupposes that the characters of war, namely soldiers and military officers, are human beings. Warfare has, however, changed increasingly since the Geneva Conventions were wr

Screening for infection by the endosymbiotic bacteria Wolbachia pipientis in Russian Melitaea butterflies

Do Russian Melitaea butterflies contain the symbiotic bacteria Wolbachia? Background Up to 60 percent of insect species in the world are infected with the intracellular, obligate symbiont called Wolbachia pipientis, making it one of the most common arthropod endosymbionts, and potentially one of the most successful organisms on Earth. The bacterium affects its host species in negative and/or posi

2010 års hyresreform -nödvändig för att ej stå i strid med EU-rättens konkurrens- och statsstödsregler?

Sammanfattning Den svenska bostadshyresmarknaden präglas av en öppenhet för alla grupper i samhället. Syftet med den svenska bostadspolitiken är att skapa social, ekonomisk och etnisk mångfald i alla stadsdelar genom att kunna erbjuda prisvärt boende samt hyra oavsett inkomst. För att nå detta mål, införde Sverige samma hyressättningssystem för alla typer av bostäder, oavsett om de tillhandahölls Summary The Swedish housing market is characterized by being accessible to all groups in society and by the objective of achieving an overall social cohesion in its rental market. The purpose of this is to further integration and counter segregation by creating diverse neighborhoods accessible to all groups in society regardless of social status and for a reasonable price. To reach this goal, Swed

Mapping wetlands in Sweden using multi-source satellite data and random forest algorithm

Wetlands are valuable ecosystems, and assets for human life, that must be regularly monitored, starting with accurately mapping their location and extent. However, an updated national inventory of wetlands is needed. The availability of multi-source data, and advanced machine learning algorithms in Google Earth Engine (GEE) offers excellent opportunities to map wetlands on a country-wide scale. Th

Trådar av historien : en studie av bevarandet av textilt kulturarv i arkiv

This master’s thesis aims to illuminate how the textile cultural heritage such as textiles and the documentation about textiles is currently preserved in archives. This is a field of study that is currently absent in the research of archival science and research in general. Three archives with material connected to textile cultural heritage were interviewed for this study. To answer how textile cu

The Role of Nik-related kinase in Regulating IL-10 Expression

Nik-related kinase: A New IL-10 Regulator Our body is constantly exposed to microscopic organisms called microbes. Some of these organisms are harmless while others are able to cause infection and damage. Thus, our body has defense mechanisms that include the immune system. Macrophages are cells that belong to the immune system and have key roles in defense against infection, wound healing, and r

A Mega Impact on a Nanoscale

In nature, for example through mechanical degradation (e.g., plastic waste in the sea) and through the exposure to UV-radiation, plastics can degrade to microplastics and eventually to even smaller plastic nanoparticles. Studies performed under laboratory conditions have shown that plastic nanoparticles can accumulate in the liver and the brain of fishes, hence plastic nanoparticles can cause brai

Wisdom in absence of a crowd

Purpose: The purpose of this study is to investigate what factors, if any, are most prevalent in the valuation of small cap stocks, with limited ownership as compared to their fundamental values, where crowd based trading and insights do not necessarily prevail. Methodology: A deductive and comparative study realized in quantitative research based upon a sample selection of smaller companies. Find

Molecular Characterization of High β-Glucan Lines in Oats

Oats (Avena sativa) are part of the cereal whole grain family, and their production is on the rise for the past few years due to extensive research done on the health benefits it can provide to humans. ScanOats project in Sweden is one of the research groups across the world that has done extensive work on oats. The lines CT-BG-53, CT-BG-21, and CT-BG-37 are mutant lines harvested by Crop Tailor A