Search results

PURPOSE: To analyze the effect of germline mutations in BRCA1 and BRCA2 on mortality in patients with ovarian cancer up to 10 years after diagnosis.EXPERIMENTAL DESIGN: We used unpublished survival time data for 2,242 patients from two case-control studies and extended survival time data for 4,314 patients from previously reported studies. All participants had been screened for deleterious germlin

Popular Abstract in Swedish Levande organismer, inklusive människor, har en 14C/12C-kvot som återspeglar miljön. När materialet dör slutar kroppen att fylla på 14C och kroppens 14C börjar sönderfalla till 14N. Detta gav upphov till den klassiska 14C-dateringsmetoden, vilken utvecklades av professor W.F. Libby, 1949 och gav honom Nobelpriset i kemi 1960. 14C-datering används huvudsakligen inom arkeThe testing of nuclear weapons in the atmosphere, in the middle of the 20'h century, resulted in a bomb-pulse excess of atmospheric 14C. A bomb-pulse dating method was thus developed. The latter is a method to determine the time of formation of formerly living modern (i.e. living after 1955) material , based on the 14C/ 12C ratio in it. The objective of this work was to evaluate the factors that c

Popular Abstract in Swedish Resultaten i denna avhandling visar att kvällsmåltider baserade på hela kärnor av korn (kokta kornkärnor, kornkärnbröd), har positiva effekter på blodsocker- och aptitregleringen vid den följande frukostmåltiden, jämfört med en kvällsmåltid av vitt bröd. Även ett sent kvällsmål med bruna bönor hade liknande effekter. Vidare visade resultaten att en kvällsmåltid med brunThe role of dietary fibre (DF) in disease prevention has been extensively investigated and prospective studies observed that increased DF intake decreased the risk of cardiovascular disease (CVD), reduced the risk of weight gain as well as the risk of type 2 diabetes (T2D). Also a diet characterized by low glycaemic index (GI) has been shown to reduce the risk of T2D and CVD. More recently, eviden

Popular Abstract in Swedish Utvecklare i stora mjukvaruprojekt måste orientera sig i enorma informationslandskap. Brist på överblick innebär ett hårt slag mot produktiviteten. Mönster ifrån tidigare buggar kan guida framtida underhållsarbete.Software developers in large projects work in complex information landscapes and staying on top of all relevant software artifacts is an acknowledged challenge. As software systems often evolve over many years, a large number of issue reports is typically managed during the lifetime of a system, representing the units of work needed for its improvement, e.g., defects to fix, requested features, or

Surrogate measures of safety (SMoS) are meant to function as tools to investigate traffic safety. The term surrogate indicates that these measures do not rely on crash data; instead, they focus on identifying safety critical events (or near-crashes) in traffic, which can be used as an alternative to crash records. The overall aim of this thesis is to explore which SMoS are suitable when analysing

ObjectiveThe quality of cardiopulmonary resuscitation (CPR) affects outcomes from cardiac arrest, yet manual CPR is difficult to administer. Although mechanical CPR (mCPR) devices offer high quality CPR, only limited data describe their deployment, their interaction with standard manual CPR (sCPR), and the consequent effects on chest compression continuity and patient outcomes. We sought to descri

Background: Potent antithrombotic therapy has significantly improved prognosis for patients with acute myocardial infarction (AMI), however, at a price of increased bleeding risk. Chronic gastric infection with Helicobacter pylori (Hp) commonly causes upper gastrointestinal bleeding and is proposed as a risk factor for subsequent bleeding post AMI. The prevalence of active Hp in a current AMI popu

Introduction and hypothesis: Bilateral pelvic nerve injury (BPNI) is a model of post-radical hysterectomy neuropraxia, a common sequela. This study assessed the time course of changes to detrusor autonomic innervation, smooth muscle (SM) content and cholinergic-mediated contraction post-BPNI. Methods: Female Sprague–Dawley rats underwent BPNI or sham surgery and were evaluated 3, 7, 14, and 30 day

Popular Abstract in Swedish Att bedöma välbefinnande hos patienter med mag/tarmcancer Avhandlingen handlar om undernäring, beroende/oberoende i det dagliga livet och uppfattningar om hälsorelaterad livskvalitet hos patienter som opereras pga cancer i mag/tarmkanalen. Enligt journaldokumentation hos 45 patienter som opererades 1985-89, för cancer i bukspottkörteln, hade patienterna ett försämrat nThe aim was to study some aspects of patients´ well-being, related to nutrition, activities of daily living and health related quality of life, when undergoing major gastrointestinal cancer surgery. Chart documentations (N=45) of patients undergoing subtotal pancreatectomy were studied, and showed the patients' well-being to be affected, although it was not possible to fully evaluate the results o

Background: Following reversal of short periods of ureteral obstruction (UO), glomerular and tubular renal dysfunction recovers with time. Diabetes mellitus (DM) affects glomerular function; thus, the ability of diabetic kidneys to recover from UO may be impaired. This study investigated the effects of long-term DM on the recovery of glomerular and tubular function, as well as permeability of the

Background: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with as

Background: Most in vitro studies of potential osteoarthritis (OA) therapies have used cartilage monocultures, even though synovium is a key player in mediating joint inflammation and, thereby, cartilage degeneration. In the case of interleukin-1 (IL-1) inhibition using its receptor antagonist (IL-1Ra), like chondrocytes, synoviocytes also express IL-1 receptors that influence intra-articular IL-1

Background: The relationship between dyslipidemia, inflammation and CV organ damage in type 2 diabetes mellitus (T2DM) is complex. Insulin resistance and inflammatory cytokines interleukins (ILs) increase plasma triglycerides (TG). ILs also up-regulate expression of matrix-metalloproteinases (MMPs) that, together with TG, decrease high density lipoprotein cholesterol (HDL) levels. High TG, low HDL

Background and aims: Pharmacotherapy can be an important part of the continuum of care for alcohol use disorder (AUD). The Swedish universal health-care system emphasizes provision of care to marginalized groups. The primary aim was to test associations of neighborhood deprivation and disadvantaged social status with receipt of AUD pharmacotherapy in this context. Design: Data from linked populati

AbstractPhysical exhaustion can constrain human ascending work capacity and performance during emergency evacuation on stairs. The overall aim of this research was to explore and compare stair ascending capacities and physiological limitations during two different strategies: self-preferred pace in three different public stairways in the field, and controlled pace in a laboratory on a stair machin

BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this syst

1 LUMES Lund University International Master’s Programme in Environmental Sciences Master thesis Relevance of Physical Environment to Urban Development Natural Landscapes in Dynamics and Structure of City Space Anton Shkaruba Talstoga, 4-174, 220003, Minsk, Belarus, Tlf: +375 17 2201213, e-mail: fiumicina@yahoo.com Scientific supervisor: Hans Thor Andersen, Ph.D, Associate professor Department of

https://www.lumes.lu.se/sites/lumes.lu.se/files/shkaruba_anton.pdf - 2026-06-08

Microsoft Word - 2 nv uppsatsen 2.doc 1 1. INTRODUCTION During the early 1980’s, the term sustainable development was first introduced. Through the Brundtland Report in 1987, sustainable development was concretized, and then popularized during the Rio conference in 1992. By formulating and defining the term, the recognition of the links between economic, social and environmental sustainability is

https://www.lumes.lu.se/sites/lumes.lu.se/files/wilhelmsson_petra.pdf - 2026-06-08

1 Publications by the SAPES research environment 2010 – 2016 Ahrenfeldt, E.J., Klatt, B.K., Arildsen, J., Trandem, N., Andersson, G.K.S., Tscharntke, T., Smith, H.G. and Sigsgaard, L. 2015. Pollinator Communities in Strawberry Crops - Variation at Multiple Spatial Scales. Bulletin of Entomological Research 105, 497-506. Albizua, A., Williams, A., Hedlund, K. and Pascual, U. 2015. Crop Rotations In

https://www.cec.lu.se/sites/cec.lu.se/files/publikationslista_sapes_mars_2016.pdf - 2026-06-08

Programme syllabus Master of Science Programme in Global Studies Faculty of Social Sciences SAGLS, Master of Science Programme in Global Studies, 120 credits Masterprogram i globala studier, 120 högskolepoäng Second cycle degree programme requiring previous university study / Program med akademiska förkunskapskrav och med slutlig examen på avancerad nivå Decision The programme syllabus is establis

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/sagls_0.pdf - 2026-06-08