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The effect of strain and transforming growth factor beta on equine tendon fibroblasts (tenocytes) was assessed in vitro. Tenocytes were isolated from flexor and extensor tendons of horses from foetal to 10 years of age. These cells were cultured until confluent on collagen-coated silicone dishes. Cyclic biaxial strain of 9 +/- 1% was applied at 0.5 Hz for 24 hours with or without added TGFbeta1 or

Each autumn, large numbers of red admirals migrate throughout northern Europe,flying south, to reach areas with conditions suitable for surviving the winter. We observed the visible butterfly migration at Falsterbo peninsula, the southwesternmost point in Sweden, where red admirals are seen most autumns. ying towards the Danish coast on their way to more southern parts of Europe. Weather parameter

Ligand induced activation of the beta-receptor for platelet-derived growth factor (PDGF) leads to activation of Src family tyrosine kinases. We have explored the possibility that the receptor itself is a substrate for Src. We show that Tyr934 in the kinase domain of the PDGF receptor is phosphorylated by Src. Cell lines expressing a beta-receptor mutant, in which Tyr934 was replaced with a phenyal

-Reduced arterial compliance precedes changes in blood pressure, which may be mediated through alterations in vessel wall matrix composition. We investigated the effect of the collagen type I-alpha1 gene (COL1A1) +2046G>T polymorphism on arterial compliance in healthy individuals. We recruited 489 subjects (251 men and 238 women; mean age, 22.6+/-1.6 years). COL1A1 genotypes were determined using

Particle formation events were analysed from aerosol number size distribution data collected at a background station in southern Sweden between February 2001 and May 2004. Events occurred on about 36% of all days and were favoured by high global radiation values. The clearest events (class I, 20% of all days) were observed when the formation rate of activated hypothetical clusters around 1 nm diam

Background/Aims: We have observed a difference between patients on low-flux hemodialysis (HD) or peritoneal dialysis and patients on hemodiafiltration (HDF) or high-flux HD in the capacity of transmigrated leukocytes to mobilize CD11b in response to inflammatory stimuli compared with healthy subjects. This could be due to different interstitial chemokine concentrations. Methods: We measured concen

Artros, vår vanligaste ledsjukdom, orsakar smärta och funktionsnedsättning och drabbar främst knä, höft och fingerleder. Dagens behandling är fokuserad på smärtlindring, sjukgymnastik och eventuell ledersättning. Vid ledskada och artros bryts broskproteiner ner, och ledskador är en riskfaktor för artros, men mekanismerna som leder fram till artros är till stor del okända. Vi studerar de molekyläraOsteoarthritis (OA), the most common joint disease, causes pain and disability and mainly affects the knee, hip and finger joints. Treatment focuses on pain relief, physical therapy and eventually prosthesis. Cartilage proteins are degraded after joint injuries and in OA; joint trauma is a risk factor for OA, but the mechanisms leading to OA are mainly unknown. We study the molecular and structura

Environmental psychology conducts research, teaching and collaborations focused on the interaction between people and the environment from the perspective of the individual. The subject deals with how people experience their surroundings and are affected by them, as well as how humans affect the environment through their behaviour. The research encompasses the relationship to both the physical a

Barn- och ungdomspsykiatrin vänder sig till barn och ungdomar från 0 till 18 år och deras familjer. Forskning inom barn- och ungdomspsykiatri växer snabbt och det finns nu en stabil kunskapsbas för många av de psykiatriska tillstånden som debuterar under uppväxten. Inom barn- och ungdomspsykiatriska avdelningen vid Lunds universitet bedrivs forskning med inriktning på utvecklingsrelaterade störnBarn- och ungdomspsykiatrin vänder sig till barn och ungdomar från 0 till 18 år och deras familjer. Forskning inom barn- och ungdomspsykiatri växer snabbt och det finns nu en stabil kunskapsbas för många av de psykiatriska tillstånden som debuterar under uppväxten. Inom barn- och ungdomspsykiatriska avdelningen vid Lunds universitet bedrivs forskning med inriktning på utvecklingsrelaterade störn

Institutionen för arkeologi och antikens historia bedriver forskning och utbildning inom fyra ämnen – antikens kultur och samhällsliv, arkeologi, historisk arkeologi och historisk osteologi. Institutionen har funnits i olika former vid Lunds universitet sedan 1805 men fick sin nuvarande sammansättning 2001. Sedan 2016 rymmer institutionen även Laboratoriet för digital arkeologi (DARKLab), en infraThe Department of Archaeology and Ancient History conducts research and education in four subjects – Classical Archaeology and Ancient History, Archaeology, Historical Archaeology and Historical Osteology. The department has existed in various forms at Lund University since 1805 but was given its current composition in 2001. Since 2016, the department also houses the Laboratory for Digital Archaeo

Cirka 20 procent av svensk befolkning beräknas drabbas av allergi. Behandlingen är huvudsakligen symtomatisk. Den kausala behandlingen är hyposensibilisering. Denna behandling är omfattande och tidsödande. Vi försöker effektivisera och förbättra behandlingen av luftburen allergi genom att utveckla nya behandlingsstrategier. Vi studerar också det fysiologiska sambandet mellan allergisk rinit och as