Filetype
The aim of the present study was to analyse quantitatively, on a cat gastrocnemius preparation in vivo, the effects of i.a. or i.v. administered glyceryl trinitrate (GTN), sodium nitroprusside (SNP) or nitric oxide (NO dissolved in saline) on vascular resistance (tone) in the following consecutive vascular sections: Large-bore arterial resistance vessels (> 25 microns), small arterioles (< 25 micr
Popular Abstract in Swedish Protein kinas C (PKC) är en familj serin/treonin kinaser som har en viktig roll i regleringen av olika funktioner i cellen. PKC kan delas in i klassiska (alpha, betaI, betaII and gamma), nya (delta, epsilon, eta and theta) och atypiska (zeta and iota/lambda) isoformer beroende på skillnader i hur de regleras. När PKCalpha är inaktivt bidrar intramolekylära bindningar tiMembers of the protein kinase C (PKC) family of serine/threonine kinases play critical roles in cellular regulation. Depending on differences in regulation, PKCs can be divided into classical (alpha, betaI, betaII and gamma), novel (delta, epsilon, eta and theta) and atypical (zeta and iota/lambda) isoforms. When PKCalpha is inactive it is maintained in a closed conformation by intramolecular inte
Recent outlooks suggest a long-term relevance of internal combustion engines for both power generation and transportation. Nonetheless, stringent pollutant reduction requirements combined with new CO2 mandates draws a challenging scenario, requiring intensive research and development activities to develop and optimize combustion modes to fulfill these requirements. Among the recent advancements, t
Disturbance of ecosystems is a major factor in regional carbon budgets, and it is believed to be partly responsible for the large inter-annual variability of the terrestrial part of the carbon balance. Forest fires have so far been considered as the most important disturbance but also other forms of disturbance such as insect outbreaks or wind-throw might contribute significantly to the largely un
In areas where tectonics and weathering have hydrogeological significance, electrical methods can assist in mapping the subsurface. In this work, resistivity imaging was used to map fractures, faults and quartz veins emplaced in strongly weathered volcanic rocks. The aim was to map geological units related to the formation of groundwater systems in the Rio Artiguas basin, Nicaragua. Eight 2D resis
Aims/hypothesis: Genome-wide association studies (GWAS) have identified more than 65 genetic loci associated with risk of type 2 diabetes. However, the contribution of distorted parental transmission of alleles to risk of type 2 diabetes has been mostly unexplored. Our goal was therefore to search for parent-of-origin effects (POE) among type 2 diabetes loci in families. Methods: Families from the
In the aftermath of the nuclear weapons testing and as compared with agriculture, the forest industry has received relatively little attention in spite of its large-scale use of radiocesium- contaminated wood and water. After the Chernobyl nuclear power plant accident in 1986, numerous studies of the forest environment have been conducted with respect to radionuclide transfer through the forest ec
Popular Abstract in Swedish Många växtarter kan inte kolonisera kalkjordar och det är stora skillnader i artsammansättningen mellan kalkjordar och närliggande surare jordar. Detta beteende kallas ofta för kalkskyende och tycks orsakas av en oförmåga hos dessa växtarter att lösa och ta upp fosfat och järn ur kalkjordar. Kalkjordar innehåller mycket låga halter av järn och fosfat löst i marklösninge
It’s been 34 years ago now since the iron curtain has parted the European continent and its inhabitants in an East and a West. The analysed area for the following thesis on the border between northern Austria and southern Czechia gives a case example of a region, that is still suffering from an era, where one sky-direction has been erased from people’s everyday living and thinking – leaving the bo
With the climate change and urbanization process, the frequency of the urban flooding’s occurrence has increased in the recent years. It brings great economic losses to the cities, especially to the basements of individual properties. Low Impact Development (LID), which currently advocated by more city planners for managing stormwater, is considered as a more sustainable way to mitigate urban floo
Friedriech's ataxia is a serious neurological condition that is caused by a deficiency in the expression of the protein frataxin. This deficiency is caused by an extension of GAA repeats in the first intron of the frataxin-coding gene. The disease can have an onset as early as five years and by the time the patient has reached 20 years they often require a wheelchair and help to be able to hav
A part of the project of transforming the worn down medieval fortress Glimmingehus into a tourist attraction for the people of the 20th century, was to dig out the once filled in moat surrounding it. This very labour intensive project did not only result in a nostalgic atmosphere but also a large amount of fairly well preserved finds, since the moat had once been used as a rubbish dump. A part of
It is impossible to conceive our modern world without plastics. Since the mass production of plastics began, humanity has produced around 8 billion tons of plastic waste, and only 9% has been recycled. Terephthalic acid polymers such as poly(ethylene terephthalate) (PET) have been massively produced over the last years thanks to their characteristics and applications. Due to their limited biodegra
China’s rapid economic development has led to a continuously increasing energy demand and the country is the world’s biggest energy user as of today. The country accounts for around 23% of the global energy production, but 70% of the Chinese energy is generated with coal power and China is the biggest emitter of CO2 in the world. The Chinese government has set a couple of goals to reduce the count
The genus Caldicellulosiruptor and especially Caldicellulosiruptor saccharolyticus are gaining attention because of their potential as biohydrogen producers from agricultural and forestry waste on an industrial scale. Genetic and in turn metabolic engineering can be used to aid in the characterization of C. saccharolyticus. Additionally, it can be used in strain improvement to overcome limiting fa
Water chemistry alterations such as acidification and eutrophication represent major threats to the running waters of the world, and Swedish waters are among the most vulnerable. In this study the small forested catchment Storskogen, part of the SWETHRO monitoring network, was analysed to examine the links between deposition, catchment hydrological properties and surface water chemistry. Storskoge
