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Popular Abstract in Swedish Den här avhandlingen består av fem papper (A-E) som samtliga är tillämpningar av Rice's formel. Tillämpningsområdena är inom oceanografi och miljö. De tre första papperna behandlar egenskaper hos mötande havsvågor, det vill säga vågor som ett fartyg möter när det seglar på havet. Papper A syftar till att hitta en formel för att räkna ut intensiteten av sådana vågor. SpThis thesis is based on five papers (A-E), all treating various applications of Rice's formula. The areas of application are oceanographic and environmental problems. The first three papers treat properties of encountering waves, that is, waves that a ship encounters while sailing on the ocean. Paper A addresses the problem of computing the intensity of such waves and, in particular, the intensit

PURPOSE: A previous study has shown age- and sex-related differences in abdominal aortic compliance. In that study blood pressure determined by auscultation in the brachial artery was assumed to be equal to blood pressure in the abdominal aorta. To validate our findings we investigated the pressure-diameter (P-D) relationship of the abdominal aorta. METHODS: Diameter and pulsatile diameter change

Testicular germ cell tumours (TGCT) exhibit remarkable ability to differentiate into virtually all somatic tissue types. In this study, we investigated changes in mucin-type O-glycosylation, which have been associated with somatic cell differentiation and cancer. Expression profile of simple mucin-type O-glycans (Tn, sialyl-Tn, T), histo-blood group H and A variants and six polypeptide Ga1NAc-tran

Dynamic models complement existing time series of observations and static critical load calculations by simulating past and future development of chemistry in forest and lake ecosystems. They are used for dynamic assessment of the acidification and to produce target load functions, that describe what combinations of nitrogen and sulfur emission reductions are needed to achieve a chemical or biolog

Ectomycorrhizal (EM) fungi are known to colonize minerals in forest soil, and in many laboratory experiments it has been confirmed that EM fungi stimulate dissolution of minerals such as apatite, biotite and feldspars. However, due to the low number of experiments performed in the field, and in forests with different soil fertilities, it is difficult to conclude whether this effect has any ecologi

Depth data and bathymetry maps are used to analyze their association with tides, winds, currents and wave conditions in the port of Talara, at the coast of northern Peru. The objective is to investigate the processes that influence the sediment transport in the port. The sedimentation affects the saltwater pumps for fire fighting, obstructing them from delivering water since their operational wate

Enzyme engineering for a better future It is essential for many organisms on this planet to be able to digest plants. One of those organisms is the blue mussel, which uses certain enzymes in its stomach to break down sugar fibers in the algae that it eats. But how does this really work, and can we use it for anything? Plant cells have very strong walls, protecting them from environmental stress.

The idea of energy efficient, healthy buildings has existed since 1970s. However, a one-dimensional approach for many housing issues does not assure sustainability. Therefore, near the end of the 20th century, the built environment became a focus of attention within the environmental movement with wider focus on building certification schemes and sustainability issues such as interrelationships be

On their route to tropical Africa, European trans-Saharan migrants must cross two major geographical barriers, the Mediterranean Sea and the Sahara Desert, which necessitates the accumulation of large fuel loads. While northern Africa is the chief region where most migrants gain fuel for the Sahara crossing, Iberia is a target area to gain fuel before the sea crossing existing between Europe and A

Background. Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of B-cell lymphomas. Five clinical adverse risk factors are merged into the International Prognostic Index (IPI), which is the major tool for prognostication. In contrast to Hodgkin's lymphoma, gender is not considered as an adverse risk factor for DLBCL patients. As we clinically had observed a very good survival rate in y

P>Aims Type 1 diabetes mellitus (T1DM) is an autoimmune disease with potential mechanistic links to immune-related cancers. We aimed at examining the overall and specific cancer risks among hospitalized T1DM patients from the national registers in Sweden. Methods A T1DM research cohort was created by identifying T1DM patients from the Hospital Discharge Register and linking them with the Cancer Re

Background: Alzheimer's disease (AD) is associated with deposition of amyloid beta (A beta) in the brain, which is reflected by low concentration of the A beta 1-42 peptide in the cerebrospinal fluid (CSF). There are at least 15 additional A beta peptides in human CSF and their relative abundance pattern is thought to reflect the production and degradation of A beta. Here, we test the hypothesis t

BACKGROUND: Galectins, a family of small carbohydrate binding proteins, have been implicated in regulation of inflammatory reactions, including asthma and fibrosis in the lungs. Galectins are found in cells of the airways and in airway secretions, but their glycoprotein ligands there have only been studied to a very limited extent. METHODS: Bronchoalveolar lavage (BAL) fluid from mild asthmatics a

This thesis aimed to investigate possibilities to utilize death certificates in cancer epidemiology by analyzing nationwide databases from Sweden. Excessive information is available when investigating causes of death in cancer patients, including comorbidities and metastatic patterns. We used the Swedish Family- Cancer Database, which includes data from e.g. the Cause of Death Register and the Can

In order to describe the influence of Pleistocene glaciations on the genetic structure and demography of a highly mobile, but specialized, passerine, the Savi’s Warbler (Locustella luscinioides), mitochondrial DNA sequences (ND2) and microsatellites were analysed in c.330 individuals of 17 breeding and two wintering populations. Phylogenetic, population genetics and coalescent methods were used to

Atherosclerosis is a chronic inflammatory disease and the leading cause of myocardial infarction and stroke. Accumulation, aggregation and subsequent oxidation of LDL in the arterial wall are considered as key events in the development of atherosclerosis. The oxidation of LDL generates reactive aldehydes, including malondialdehyde (MDA) that modifies ApoB in LDL. Immune responses against MDA-modif

Our study had three objectives: to extend the plasmid-based transformation protocol to a clinical isolate of C. trachomatis belonging to the trachoma biovar, to provide "proof of principle'' that it is possible to "knock out'' selected plasmid genes (retaining a replication competent plasmid) and to investigate the plasticity of the plasmid. A recently developed, plasmid-based transformation proto