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Assessing heterogeneous effects and their determinants via estimation of potential outcomes

When analyzing effect heterogeneity, the researcher commonly opts for stratification or a regression model with interactions. While these methods provide valuable insights, their usefulness can be somewhat limited, since they typically fail to take into account heterogeneity with respect to many dimensions simultaneously, or give rise to models with complex appearances. Based on the potential outc

Cerebral palsy in extremely preterm infants

Background and Objectives: The risk of cerebral palsy (CP) is high in preterm infants and is often accompanied by additional neurodevelopmental comorbidities. The present study describes lifetime prevalence of CP in a population-based prospective cohort of children born extremely preterm, including the type and severity of CP and other comorbidities (ie, developmental delay and/or cognitive impair

Application of positive matrix factorization (PMF) to real time aerosol mass spectrometry measurements in an occupied apartment in Sweden

Introduction Given that in developed countries we spend about 65% of our time in private homes (Brasche et al. 2005), understanding the exposures in homes is of outmost importance. Airborne particle concentrations indoors can be affected by particles of indoor and outdoor origins, as well as physico-chemical processes indoors, outdoor infiltration affected by tightness of the building envelope and

Characteristics of Particulate Emissions from Low Temperature Combustion and Renewable Fuels : Aerosol Mass Spectrometry of Refractory Carbonaceous Particles

Particulate air pollution is one of the major causes of premature death in the world, and combustion-derived soot emissions contribute strongly to the particulate pollution to which humans are exposed. Black carbon (BC) is one such emission and denotes soot with strong light absorption in the ultraviolet to infrared spectrum. Combustion can also generate brown carbon (BrC) particles, with absorpti

ICARUS -- An Extensible Graphical Search Tool for Dependency Treebanks

We present ICARUS, a versatile graphical search tool to query dependency treebanks. Search results can be inspected both quantitatively and qualitatively bymeans of frequency lists, tables, or dependency graphs. ICARUS also ships with plugins that enable it to interface with tool chains running either locally or remotely.

Economic Evaluation of Elective Cesarean Section on Maternal Request Compared With Planned Vaginal Birth—Application to Swedish Setting Using National Registry Data

Objectives: There is a lack of consensus around the definition of delivery by cesarean section (CS) on maternal request, and clinical practice varies across and within countries. Previous economic evaluations have focused on specific populations and selected complications. Our aim was to evaluate the cost-effectiveness of CS on maternal request compared with planned vaginal birth in a Swedish cont

Pulmonary embolism and deep venous thrombosis after COVID-19 : long-term risk in a population-based cohort study

Background: Venous thromboembolism (VTE) (pulmonary embolism [PE] or deep venous thrombosis [DVT]) is common during acute COVID-19. Long-term excess risk has not yet been established. Objectives: To study long-term VTE risk after COVID-19. Methods: Swedish citizens aged 18 to 84 years hospitalized and/or testing positive for COVID-19 between January 1, 2020, and September 11, 2021 (exposed), strat

English dictionaries, gold and silver standard corpora for biomedical natural language processing related to SARS-CoV-2 and COVID-19

Here we present a toolbox for natural language processing tasks related to SARS-CoV-2. It comprises English dictionaries of synonyms for SARS-CoV-2 and COVID-19, a silver standard corpus generated with the dictionaries and a gold standard corpus of 10 Pubmed abstracts manually annotated for disease, virus, symptom and protein/gene terms. This toolbox is freely available on github and can be used f

COVID-19 in people aged 18–64 in Sweden in the first year of the pandemic : Key factors for severe disease and death

Background: Studies on risk factors for severe COVID-19 in people of working age have generally not included non-working persons or established population attributable fractions (PAFs) for occupational and other factors. Objectives: We describe the effect of job-related, sociodemographic, and other exposures on the incidence, relative risks and PAFs of severe COVID-19 in individuals aged 18–64. Me

Obstetric anal sphincter injuries—Maternal, fetal and sociodemographic risk factors : A retrospective register-based study

Introduction: Obstetric anal sphincter injuries (OASIS) are severe complications to vaginal births with potentially serious long-term consequences and large impact on quality of life. The aim was to determine risk and protective factors for OASIS. Material and methods: We performed a retrospective register-based observational study. A cohort of 988 988 singleton term deliveries 2005–2016 in Sweden

Severe COVID-19 in people 55 and older during the first year of the pandemic in Sweden

Background: Exposure to many contacts is the main risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, while risk of serious disease and death is chiefly determined by old age and comorbidities. Relative and population-attributable fractions (PAFs) of multiple medical and social exposures for COVID-19 outcomes have not been evaluated among older adults. Objective

The influence of ignition control parameters on combustion stability and spark plug wear in a large bore gas engine

The paper presents novel studies on the impact of different ignition control parameters on combustion stability and spark plug wear. First, experimental results from a 32.4-liter biogas fueled large bore single cylinder spark ignition engine are discussed. Two different ignition systems were considered in the experiment: a DC inductive and an AC capacitive. The spark plugs used in the experiment w

A multi-program analysis of cleft lip with cleft palate prevalence and mortality using data from 22 International Clearinghouse for Birth Defects Surveillance and Research programs, 1974–2014

Background: Cleft lip with cleft palate (CLP) is a congenital condition that affects both the oral cavity and the lips. This study estimated the prevalence and mortality of CLP using surveillance data collected from birth defect registries around the world. Methods: Data from 22 population- and hospital-based surveillance programs affiliated with the International Clearinghouse for Birth Defects S

Neurobehavioral symptoms in children born extremely preterm : A Swedish National Study

Aim: To determine the prevalence of neurobehavioral symptoms at 6.5 years in children born extremely preterm (EPT, <27 weeks' gestation). Methods: Population-based cohort study of infants born EPT in Sweden from 2004 to 2007. Of 486 survivors 375 were assessed and compared with 369 matched term-born controls. EPT children free from neurosensory and intellectual disabilities (neurodevelopmental dis

The role of primary care in the cancer care continuum : a qualitative study of cancer survivors’ experiences

Objective: To explore how cancer survivors have experienced their contacts with primary care after being diagnosed with cancer, focusing on the integration between cancer specialist and primary care, and participants’ views on what could make primary care services better at catering to the needs of cancer survivors. Design: A qualitative study in which data was collected through semi-structured di

Improving commuter train punctuality using lead indicators

Train delays are often monitored using lag indicators of achieved punctuality levels, but indicators can also be used proactively as lead indicators to help reach a certain level of punctuality. In this paper, two lead indicators – the share of delayed dwell times and the share of delayed run times – are formulated and tested on Swedish commuter train data for the years 2001-2020. Results show tha

ὑστερέω and πίστις Χριστοῦ in Romans 3:23 : A Response to Steven Enderlein

This article is a response to Steven Enderlein on the translation of Rom 3:23 and its implications for the πίστις Χριστοῦ debate. While affirming Enderlein's suggestion that the verb ὑστερέω is better understood as “lack” rather than “fall short,” we argue against his conclusions (1) that this translation leads to a subjective genitive reading of πίστις Χριστοῦ in Rom 3:22, 26; and (2) that the ve

Speaking in a Situation : Ovid and the Ethopoeia

The Augustan poet Ovid (43 BC – AD 17/18) is mentioned by Seneca the elder for his oratorical skills as a school boy. If we are to believe Seneca, Ovid excelled to such a degree that he even surpassed his teachers. He took special interest in exercises concerning ethos, and is said to have transferred what he learned into his own verse. The influence from rhetorical training is indeed visible in O