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B-cell progenitor acute lymphoblastic leukemia (BCP-ALL) is the most common childhood malignancy and is driven by multiple genetic alterations that cause maturation arrest and accumulation of abnormal progenitor B cells. Current treatment protocols with chemotherapy have led to favorable outcomes but are associated with significant toxicity and risk of side effects, highlighting the necessity for

Pseudouridine synthases (PUSs) catalyze the isomerization of uridine (U)-to-pseudouridine (Ψ) and have emerging roles in development and disease. How PUSs adapt gene expression under stress remains mostly unexplored. We identify an unconventional role for the Ψ "writer" PUS10 impacting intracellular innate immunity. Using Pus10 knockout mice, we uncover cell-intrinsic upregulation of interferon (I

BACKGROUND: Skin cancer is a prevalent and clinically significant condition, with early and accurate diagnosis being crucial for improved patient outcomes. Dermoscopy and artificial intelligence (AI) hold promise in enhancing diagnostic accuracy. However, the impact of image quality, particularly high dynamic range (HDR) conversion in smartphone images, on diagnostic performance remains poorly und

Early diagnosing and patient individualized biomarker profiling are two key elements for curative interventions within cancer. Detecting cancer, when the tumor is still localized, allows for a more efficient treatment-either through surgery alone or with systemic therapies, treating a naïve and less heterogeneous tumor cell population. Developing tumors consist of complex and stage-dependent genet

Popular Abstract in Swedish I inledningen till detta arbete ställer jag några frågor, såsom vilka filosofiska och teologiska förutsättningar som påverkar Wingrens teologi, om han är medveten om dessa och är kritisk till dem. Detta är viktigt eftersom huvudsyftet med avhandlingen är att spåra de grundläggande tankeförutsättningarna hos honom. Wingren själv anser att tron är förutsättning för det teThe purpose of this study is to represent and critically analyse the theology of the Swedish theologian and professor in Lund, Gustaf Wingren (1910-2000), with special reference to his confrontational views on the role of theology at the university, in society and in church. The Lundensian school was famous for demonstrating a strictly scientific character of theology as an objective argumentation

Popular Abstract in Swedish Lyhördhet. Studenters uppfattningar av lyhördhet i omvårdnad och utbildningAvhandlingen handlar om lyhördhet i omvårdnad och utbildning. Ett problem är att ordet lyhördhet endast finns på de nordiska språken. I engelska, tyska och franska ordböcker omskrivs lyhördhet på olika sätt utan att egentligen ges hela den betydelse som det har i nordiska språk. I engelskan översThe word lyhördhet has its origin in Danish and exists only in the Nordic languages. In this summary the Swedish word is used in italics without translation.The subject of this dissertation is lyhördhet in nursing education, what lyhördhet can be and how it can be made a valuable part of educations involving care of human beings, in particular nursing education.The term lyhördhet has not previousl

Infrared excesses associated with debris disk host stars detected so far peak at wavelengths around ~100 μm or shorter. However, 6 out of 31 excess sources studied in the Herschel Open Time Key Programme, DUNES, have been seen to show significant—and in some cases extended—excess emission at 160 μm, which is larger than the 100 μm excess. This excess emission has been attributed to circumstellar d

An atomistic understanding of the photoinduced spin-state switching (PSS) within polynuclear systems of d4-d7 transition metal ion complexes is required for their rational integration into light-driven reactions of chemical and biological interest. However, in contrast to mononuclear systems, the multidimensional dynamics of the PSS in solvated molecular arrays have not yet been elucidated due to

The DAΦNE electron-positron collider of the Laboratori Nazionali di Frascati of INFN is a worldwide unique low-energy kaon source, which is being used to produce and to study kaonic atoms by the SIDDHARTA collaboration. The X-ray measurements of kaonic atoms play an important role for understanding the low-energy QCD in the strangeness sector. Significant achievements have been obtained by the SID

Direct reprogramming of immune cells holds promise for immunotherapy but is constrained by limited knowledge of transcription factor (TF) networks. Here, we developed REPROcode, a combinatorial single-cell screening platform to identify TF combinations for immune cell reprogramming. We first validated REPROcode by inducing type-1 conventional dendritic cells (cDC1s) with multiplexed sets of 9, 22,

Background: Diabetes is presently classified into two main forms, type 1 and type 2 diabetes, but type 2 diabetes in particular is highly heterogeneous. A refined classification could provide a powerful tool to individualise treatment regimens and identify individuals with increased risk of complications at diagnosis. Methods: We did data-driven cluster analysis (k-means and hierarchical clusterin

Atopic dermatitis (AD) is a complex disease with elevated risk of respiratory comorbidities.1,2 Severely affected patients are often treated with immune-modulating systemic drugs.3,4 On March 11th 2020, the World Health Organization declared the 2019 novel coronavirus severe acute respiratory syndrome (SARS-Cov-2) epidemic to be a pandemic. The number of cases worldwide is increasing exponentially

a k t u el lt o m v e t ensk a p o ch h ä l sa • n ov 20 0 6 Nya vägar för cancer- behandling November 2006 Denna tidskrift ges ut av Medicinska fakulteten vid Lunds universitet och Universitetssjukhuset i Lund & Universitetssjukhuset MAS vid Region Skåne Aktuellt om Vetenskap & hälsa a k t u el lt o m v e t ensk a p o ch h ä l sa • n ov 20 0 6 in sig på egenskaper, signaler och mekanismer som b

https://www.vetenskaphalsa.se/wp-content/uploads/2010/08/Aktuellt-om-vet-o-h%C3%A4lsa-06.pdf - 2026-05-28

IDENTIFIKASI TAUTAN INDIKATOR KABUPATEN/KOTA PEDULI HAM DAN SDGs Ketua Tim Penyusun: Dr. Mualimin Abdi, S.H., M.H. Tim Penyusun: Hajerati | Bambang Iriana Djajaatmadja | Prahesti Pandanwangi Andi Taletting Langi | Tanti Dian Ruhama | Sofia Alatas | Hidayat Yasin Relly Listriana Susan | Masri Tajuddin | Andi Muttaqien Ibrahim Reza | Luther Budi Raja Purba | Yusuf Romli Ikhwan Setiawan Pranata | Dew

https://rwi.lu.se/wp-content/uploads/2024/06/Identifikasi-Tautan-KKPHAM-dan-SDGs.pdf - 2026-05-28

Asylum Seeker Situation Urgent in Europe Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights Internat

https://rwi.lu.se/2015/04/21/asylum-seeking-situation-urgent/ - 2026-05-29

Bilaga 1 Saco-S föreningen i Specialpedagogiska skolmyndigheten Verksamhetsberättelse 2023 för Saco-S föreningen i Specialpedagogiska skolmyndigheten Verksamhet under tiden 1 januari 2023 till 31 december 2023 Bilaga 1 Saco-S föreningen i Specialpedagogiska skolmyndigheten Styrelse under 2023 Ordförande Ingrid Mauritsson, ombud MSG Vice ordförande Anna Nordesjö, ombud MSG Andre vice ordförande Jen

https://www.saco.se/contentassets/9ffcb08ee87844a5af2ed9fc6e2afd74/saco-s-verksamhetsberattelse-for-verksamhetsaret--2023.pdf - 2026-05-29

A Z A H A R M O N G E Partitioned m ethods for tim e-dependent therm al fluid-structure interaction 2018 Doctoral Theses in Mathematical Sciences 2018:5 ISBN 978-91-7753-775-5 ISSN 1404-0034 Partitioned methods for time-dependent thermal fluid-structure interaction AZAHAR MONGE Lund University Faculty of Science Centre for Mathematical Sciences Numerical Analysis – CE N T R U M S C I E N T I A R U

https://www.maths.lu.se/fileadmin/maths/Azahar_Monge_WEBB.pdf - 2026-05-29

This roadmap, developed through collaborative discussions at the recent AI PolicyResearch Summit, reflects a shared vision for advancing research on responsibleAI policy and governance. It emphasizes the critical role of policy research inensuring that AI development is guided by robust evidence, ethicalconsiderations, and a commitment to sustainability and inclusivity. By prioritizingtransparency