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Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

Fusion genes are potent driver mutations in cancer. In this study, we delineate the fusion gene landscape in a consecutive series of 195 paediatric B-cell precursor acute lymphoblastic leukaemia (BCP ALL). Using RNA sequencing, we find in-frame fusion genes in 127 (65%) cases, including 27 novel fusions. We describe a subtype characterized by recurrent IGH-DUX4 or ERG-DUX4 fusions, representing 4%

PHENIX central arm tracking detectors

The PHENIX tracking system consists of Drift Chambers (DC), Pad Chambers (PC) and the Time Expansion Chamber (TEC). PC1/DC and PC2/TEC/PC3 form the inner and outer tracking units, respectively. These units link the track segments that transverse the RICH and extend to the EMCal. The DC measures charged particle trajectories in the r-phi direction to determine P-T of the particles and the invariant

Review of particle physics

This biennial Review summarizes much of Particle Physics Using data from previous editions, plus 2205 new measurements from 667 papers, we list, evaluate, and average measured properties of gauge bosons, leptons, quarks, mesons, and baryons We also summarize searches for hypothetical particles such as Higgs bosons, heavy neutrinos, and supersymmetric particles All the particle properties and searc

GISCOME – Genetics of Ischaemic Stroke Functional Outcome network : A protocol for an international multicentre genetic association study

Introduction: Genome-wide association studies have identified several novel genetic loci associated with stroke risk, but how genetic factors influence stroke outcome is less studied. The Genetics of Ischaemic Stroke Functional outcome network aims at performing genetic studies of stroke outcome. We here describe the study protocol and methods basis of Genetics of Ischaemic Stroke Functional outco

The GALAH survey : A catalogue of carbon-enhanced stars and CEMP candidates

Swan bands-characteristic molecular absorption features of the C2 molecule-are a spectroscopic signature of carbon-enhanced stars. They can also be used to identify carbonenhanced metal-poor (CEMP) stars. The GALAH (GALactic Archaeology with Hermes) is a magnitude-limited survey of stars producing high-resolution, high-signal-to-noise spectra. We used 627 708 GALAH spectra to search for carbon-enh

How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer

In early breast cancer, a preoperative core-needle biopsy (CNB) is vital to confirm the malignancy of suspected lesions and for assessing the expression of treatment predictive and prognostic biomarkers in the tumor to choose the optimal treatments, emphasizing the importance of obtaining reliable results when biomarker status is assessed on a CNB specimen. This study aims to determine the concord

Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems

Toxin-antitoxins (TAs) are prokaryotic two-gene systems composed of a toxin neutralized by an antitoxin. Toxin-antitoxin-chaperone (TAC) systems additionally include a SecB-like chaperone that stabilizes the antitoxin by recognizing its chaperone addiction (ChAD) element. TACs mediate antiphage defense, but the mechanisms of viral sensing and restriction are unexplored. We identify two Escherichia

Eosinophils—from cradle to grave

Over the past years, eosinophils have become a focus of scientific interest, especially in the context of their recently uncovered functions (e.g. antiviral, anti-inflammatory, regulatory). These versatile cells display both beneficial and detrimental activities under various physiological and pathological conditions. Eosinophils are involved in the pathogenesis of many diseases which can be class

Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study

BackgroundThe Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic

The centrality of doubting and checking in the network structure of obsessive-compulsive symptom dimensions in youth

Objective. Obsessive-compulsive disorder (OCD) is a heterogeneous condition with well-established symptom dimensions across the lifespan. The objective of the present study was to use network analysis to investigate the internal structure and central features of these dimensions in unselected schoolchildren and in youth with OCD.Method. We estimated the network structure of OCD symptom dimensions

Solvent-Dependent Structural Dynamics in the Ultrafast Photodissociation Reaction of Triiodide Observed with Time-Resolved X-ray Solution Scattering

Resolving the structural dynamics of bond breaking, bond formation, and solvation is required for a deeper understanding of solution-phase chemical reactions. In this work, we investigate the photodissociation of triiodide in four solvents using femtosecond time-resolved X-ray solution scattering following 400 nm photoexcitation. Structural analysis of the scattering data resolves the solvent-depe

In Situ Detection of Programmed Cell Death Protein 1 and Programmed Death Ligand 1 Interactions as a Functional Predictor for Response to Immune Checkpoint Inhibition in NSCLC

Introduction: Immune checkpoint inhibitors (ICIs) have transformed lung cancer treatment, yet their effectiveness seem restricted to certain patient subsets. Current clinical stratification on the basis of programmed death ligand 1 (PD-L1) expression offers limited predictive value. Given the mechanism of action, directly detecting spatial programmed cell death protein 1 (PD1)–PD-L1 interactions m

Effect of Aluminium content on oxidation behavior of arc melted AlxCoCrFeNi (x=0,0.3,0.6,1 mole) high entropy alloys exposed at 1150ºC and comparison with nanocrystalline Al0.6CoCrFeNi high entropy alloy

High entropy alloys (HEA) containing Al and Cr have been observed to manifestimpressive dry air oxidation resistance. But the testing temperature attempted inthe previous works has been restricted up to 1050ºC. In the present work AlxCoCrFeNi HEAs (x=0,0.3,0.6,1 mole) synthesized by arc melting route have beensubjected to rigorous dry air oxidation test up to 1150ºC. The as cast HEAs withx=0 and x

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KANDRIC HIN A IR IN A N IK OLAEVNA, VEREMEYCHIK O LGA VALERYEVNA, BEZBOZHNA O LGA M YKOLAEVNA SUMMARY OF GENDER AUDIT RESULTS AT THE FACULTY OF MANAGEMENT TECHNOLOGIES AND HUMANITARIZATION AT THE BELARUSIAN NATIONAL TECHNICAL UNIVERSITY ENDER OCUS E N D E R O C U S KANDRIC HIN A IR IN A N IK OLAEVNA, VEREMEYCHIK O LGA VALERYEVNA, BEZBOZHNA O LGA M YKOLAEVNA SUMMARY OF GENDER AUDIT RESULTS AT THE F

https://rwi.lu.se/wp-content/uploads/2020/12/2020.12.10-_-GENDER-in-FOCUS-eng-___-online.pdf - 2026-05-17

Trygg i starten, stark i längden

Trygg i starten, stark i längden Trygg i starten, stark i längden – Vikten av introduktion för nyexaminerade En rapport från Saco i samarbete med Saco studentråd Trygg i starten, stark i längden Vikten av introduktion för nyexaminerade Hedvig Modin © Hedvig Modin och Karin Fristedt Saco 2025 www.saco.se 1 Innehåll Sammanfattning 2 Nuläge och forskning 3 Starten i arbetslivet 3 Framgångsfaktorer fö

https://www.saco.se/contentassets/d8e1a375defd4210b27781576f0f1e4c/trygg-i-starten-stark-i-langden---vikten-av-introduktion-for-nyexaminerade_saco-2025.pdf - 2026-05-17

25-H_Modin_mfl

25-H_Modin_mfl LTHs 7:e Pedagogiska Inspirationskonferens, 30 augusti 2012 Abstract—Det har tidigare rapporterats att det finns skillnader i vad manliga och kvinnliga doktorander förväntar sig av handledningen och hur nöjda de är med sin situation. För att undersöka detta samt se om dessa skillnader kan identifieras vid LTH har tre studier genomförts; en enkätstudie bland doktorander, en intervjus

https://www.lth.se/fileadmin/lth/genombrottet/konferens2012/52_Modin_etal.pdf - 2026-05-17

Damsgård_etal

Damsgård_etal The 2nd EuroSoTL conference, June 8-9 2017, Lund, Sweden Are learning outcomes affected by course intensity and workload? B. Damsgård, E. Strømseng & Ø. Varpe The University Centre in Svalbard (UNIS), P.O. Box 156, 9171 Longyearbyen, Norway ABSTRACT: University courses may be organized as parallel semester courses, or as sequential intensive courses ranging from a few weeks to severa

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Damsga__rd_etal.pdf - 2026-05-16

PooleHeather_etal_mod

PooleHeather_etal_mod The 2nd EuroSoTL conference, June 8-9 2017, Lund, Sweden Disrupting the calendar: Measuring the impacts of a week- long fall break on stress and academic success in undergraduate students H. Poole, University of Ottawa, A. Khan, M. Agnew, I. Ghilic, and A. Smith, McMaster University ABSTRACT: The mental health of post-secondary students has received recent attention as popula

https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Poole_etal.pdf - 2026-05-16

Riktlinjer gällande examina och utbildning på grundnivå och avancerad nivå vid Lunds universitet. Be

Riktlinjer gällande examina och utbildning på grundnivå och avancerad nivå vid Lunds universitet Sida 1 av 1 FÖRSÄTTSSIDA STYRDOKUMENT Riktlinjer gällande examina och utbildning på grundnivå och avancerad nivå vid Lunds universitet Typ av styrdokument: Riktlinjer Definition av typen av styrdokument: Riktlinjer fastställer hur någon ska eller bör handla inom det område riktlinjerna omfattar. En ska

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2025-10/riktlinjer-gallande-examina-och-utbildning-pa-grundniva-och-avancerad-niva-vid-lunds-universitet.pdf - 2026-05-16

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Matematikcentrum Matematik NF Sammanställning för MATA22 Lineär algebra 1, vårterminen 2020 Kursansvarig: Anna-Maria Persson Övriga lärare: Henrik Ekström Antal studenter: 63 nyregistrerade samt 27 omregistrerade. 21 studenter har svarat på utvärderingen. Resultat på examinerande moment: - Projektuppgifter: 48 studenter klara med samtliga inlämningsuppgifter - Skriftlig tentamen: 44 godkända stude

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2020/MATA22CAVT2020.pdf - 2026-05-16