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BackgroundA machine-learning approach identified five subgroups of diabetes in Europeans which included severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), mild obesity-related diabetes (MOD) and mild age-related diabetes (MARD) with partially distinct genetic aetiologies. We previously validated four of the non-autoimmune subgroup

Understanding the attachment owners can feel to their robot vacuums, which also map and collect data about their homes, is key to understanding the ambivalences involved in the integration of automated visualities in the home. Drawing on qualitative video interviews and observations of people interacting with their robot vacuums, this article identifies three key factors in understanding how cohab

In this article we analyse the actions of Royal Dutch/Shell (since 2021, Shell) considering the campaign against them and their operations in Nigeria in the mid-1990s. Using the concept counter-frames we analyse Shell's internal documentation of the campaign to understand how a multinational extractive industry engaged in disputes of legitimacy and against critiques of their operations. Focusing o

Twenty strains of anaerobic curved rods isolated from vaginal secretion were studied with light and transmission electron microscopy. Ten of the strains were of a short (approx. 1.5 microns) Gram-variable type, while ten were of a long (approx. 3 microns) Gram-negative type. The former had one to four flagella and the latter between one and eight. The flagella originated from the concave aspect of

BACKGROUND: Asthma is characterised by an aggravated immune response to respiratory viral infections. This phenomenon is a clinically well-recognised driver of acute exacerbations, but how different phenotypes of asthma respond immunologically to viruses is unclear. OBJECTIVES: To describe the association between different phenotypes and severity of asthma and bronchial epithelial immune responses

Sustainability of the enterprise is crucial to support long-term business survival and development. Unpredictable events such as Covid-19 highlights sustainability issues in enterprises. This empirical study aims to investigate sociotechnical sustainability in real world work practices. The focus is on employee involvement and problems in work practices concerning the economic, environmental, soci

The gene for Vitreoscilla hemoglobin (VHb) has been introduced and expressed in Nicotiana tabaccum (tobacco). Transgenic tobacco plants expressing VHb exhibited enhanced growth, on average 80-100% more dry weight after 35 days of growth compared to wild-type controls. Furthermore, germination time is reduced from 6-8 days for wild-type tobacco to 3-4 days and the growth phase from germination to f

Background Safety data on cancer risks following tumour necrosis factor a inhibitors (TNFi) in patients with spondyloarthritis (SpA) (here defined as ankylosing spondylitis (AS), undifferentiated spondarthropaties (SpA UNS), psoriatic arthritis (PsA)) are scarce. Our objective was to assess risks for cancer overall and for common subtypes in patients with SpA treated with TNFi compared with TNFi-n

The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to

A mechanochemical method (grinding the components without added water - dry grinding, followed by further grinding in the presence of minute amount of water or NaOH solution - wet grinding) was used in this work for the preparation and intercalation of CaFe-layered double hydroxides (LDHs). Both the pristine LDHs and the amino acid anion (cystinate and tyrosinate) intercalated varieties were prepa

This chapter expands on three main topics. First, it is argued that the economic historical perspective may contribute to our understanding of present day development processes. Instead of advocating a one-size-fits-all model, an analytical framework is offered based on common traits from diverse examples. Second, the importance of agricultural change on the road towards sustained economic growth

Under the principle of freedom of contract, when two parties begin contract negotiations, they are under no obligation to actually arrive at an agreement and each one carries the risk for its own expenses and losses caused by the negotiations. However, even if the main rule says that each party bears the costs it might have incurred during the negotiations, if the parties do not reach an agreement

Case commentary | “Decision on the Apparent Conflict of Interests in relation to the Legal Representative of Victims a/0015/08...a/0035/08, Prosecutor v. Katanga and Ngudjolo Chui, Case No ICC-01/04–01/07, Pre-Trial Chamber I, 16 July 2008”