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Transcriptional analysis of mantle cell lymphoma - a global search for cellular origin and therapeutic targets

This thesis is based upon four original papers describing the characterisation of mantle cell lymphoma (MCL) tumours and cell lines in comparison with different populations of normal B cells. Gene expression profiling, which were used in the studies, has during recent years developed as an important tool in characterisation of different types of malignancies. In this thesis, the technique is used

Global Norms for Public Acceptance for Desalination and Water Ruse

Desalting technologies and fresh water production has been developed over the years, including primarily thermal and membrane processes. Five different types of desalination technology were studied and compared for long-term of use namely, thermal processes include multistage flash evaporation (MSF), multiple effect evaporation (ME), and vapor compression (VC) and membrane processes contain revers

Syria from Reform to Revolt : Vol. 2, Culture, Society, and Religion

As Syria’s anti-authoritarian uprising and subsequent civil war have left the country in ruins, the need for understanding the nation’s complex political and cultural realities remains urgent. The second of a two-volume series, Syria from Reform to Revolt: Culture, Society, and Religion draws together closely observed, critical and historicized analyses, giving vital insights into Syrian society t

Isomorphism, Isopraxism and Isonymism: Complementary or Competing Processes?

New institutional theory has been critizised, for describing institutionalization as a static qualitative state rather than a process. In this paper we provide an extended understanding of the process of institutionalization by replacing the mechanical concept of diffusion by the concept of translation and an analytical model of "trevel of ideas". Analyzing the field material from three cases of t

Iterative Optimal Control of Liquid Slosh in an Industrial Packaging Machine

Presents an iterative approach to optimal control when modeling errors are present. The problem considered is movement of open containers containing liquid in an industrial packaging machine. The goal is to move as fast as possible without too much slosh. There is no measurement of the slosh available in the machine, therefore open loop control via the acceleration reference is the only possibilit

Transient electromagnetic wave propagation in anisotropic dispersive media

Transient electromagnetic wave propagation in a stratified, anisotropic, dispersive medium is considered. Specifically, the direct scattering problem is addressed. The dispersive, anisotropic medium is modeled by constitutive relations (a 3 3 matrix-valued susceptibility operator) containing time convolution integrals. In the general case, nine different susceptibility kernels characterize the med

Transforming Growth Factor-b, Regulatory functions on normal lymphocytes and tumor outgrowth Regulatory functions on normal lymphocytes and tumor outgrowth

Popular Abstract in Swedish För att en multicellulär organism som männinskan ska kunna fungera måste celldelningen strikt kontrolleras. Protein som reglerar celldelning på cellulär nivå kallas för "tillväxtfaktorer". Vi har studerat ett sådant protein som kallas för transforming growth factor-beta (TGF-b). Namnet TGF-b kommer sig utav att detta protein kan transformera (omvandla) epiteliala njurceTransforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. The costimulatory effect depends on the presence of monocytes and is mediated by these cells. Furthermor

Phenomena of autonomy with explanations in introspective language

We explain autonomy with full-fledged reference to the complementaristic conception of language and its introspective capabilities. This field that we refer to is understood to belong to a wider epistemic category than that of (the received view of) semiotics as well as of systems science. It follows from the linguistic complementarity that autonomies (self-references; independencies) can never be

Study On Catalytic Reactions In Solid Oxide Fuel Cells With Comparison To Gas Phase Reactions In Internal Combustion Engines

Solid oxide fuel cells (SOFCs) have the attractive feature to be able to make use of hydrocarbon fuels in their operation by reforming the fuel into pure hydrogen, either internally or externally. This can open up for a smoother transition from the existing hydro-carbon economy toward a more renewable hydrogen economy. Since both SOFCs and internal combustion (IC) engines can make use of hydrocarb

Determination of star formation histories from gaia-type photometric and astrometric survey data

To understand the evolution of the Milky Way Galaxy requires detailed knowledge of the star formation history of various populations. The vast amounts of photometric and astrometric data provided by the Gaia mission give unprecedented opportunities in this area. The relationships between the observed data and the ages of stars are however complex and highly non-linear and great care must be taken

A differential difference comparator for multi-step A/D converters

The proposed Differential Difference Comparator (DDC) provides easy linear voltage summing/subtraction and comparison functions via current operation. The speed of this unconventional comparator drastically improved since there is no feedback loop and coupling capacitors needed to maintain the linearity. The linear input range is also enlarged by the common mode compression. The principle, design