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This edited work draws on a range of contributed expertise to trace the fortune of an Aristotelian thesis over different periods in the history of philosophy. It presents eight cases of direct or indirect challenges to the Aristotelian passive account of human cognition, taking the reader from late antiquity to the 20th century. Chapters analyse the (often indirect) effect of Aristotle’s account o
In mammals, IgA is the antibody class that is produced in largest quantities. The main producers are plasma cells located in the lamina propria at mucosal surfaces that secrete it as dimers covalently linked to the J chain. Polymeric immunoglobulin receptors (pIgRs) expressed on epithelial cells bind to dimeric IgA molecules and mediate basolateral to apical transcytosis, before IgA is released in
BackgroundCritical COVID-19 is associated with high mortality, and acute kidney injury (AKI) is common. Endostatin has emerged as a promising prognostic biomarker for predicting AKI and mortality in intensive care. This study aimed to investigate plasma endostatin at intensive care unit (ICU) admission as a biomarker for AKI, renal replacement therapy (RRT), and 90-day mortality in COVID-19.Method
Background: Acute kidney injury (AKI) is a serious complication of out-of-hospital cardiac arrest (OHCA). Post-resuscitation cardiogenic shock (CS) is a key contributing factor. Targeting a higher arterial carbon dioxide tension may affect AKI after OHCA in patients with or without CS. Methods: Pre-planned exploratory study of a multi-national randomised trial comparing targeted mild hypercapnia o
In this introduction, we explain how the chapters in this volume give support to the idea that different accounts of active cognition in the history of philosophy directly or indirectly respond to Aristotle’s account of cognition in his De anima.
In recent years, there has been a renewed interest in anarchism from both social movements and critical academic circles. When tracing the genealogy of anarchist perspectives since the nineteenth century, radical geographers have pointed out the importance of the anarchist movement in Spain, and particularly in the city of Barcelona. During the 1960s and 1970s, authors like Murray Bookchin shared
Practically all natural daytime light at the Earth’s surface originates in the Sun. The fluence rate, as well as spectral and directional distributions are modified by the gases, clouds and aerosols in the atmosphere in a way which depends on time and place, and also by vegetation, snow, and other ground-cover. A special section in this chapter is devoted to ultraviolet radiation.
REST is a transcriptional repressor that targets a group of neuronal genes in non-neuronal cells. In embryonic stem (ES) cells, REST has been implicated in controlling the expression of transcription factor genes that are crucial for lineage determination and for maintaining ES cell potential. Here, we asked whether REST directly regulates neural-specifying genes in mouse ES cells using siRNA-medi
Today an increasingly large and diverse audience spends more and more time and money on computer games; the actual player can now be anyone. Gameplay, whether it is raiding online in World of Warcraft, an evening of Guitar Hero in the living room with friends, or a quick round of Sudoku Master on the Nintendo DS while commuting home from work, has become part of the everyday life of millions of pe
Dytiscus latissimus (Coleoptera Dytiscidae) is an endangered diving beetle throughout its range. It is one of the two species of Dytiscidae listed in Annex II of the Habitats Directive, IUCN red list and in many national level legislations and therefore strictly protected. The conservation of endangered species first of all requires an assessment of their population size. Until now, a method has n
Background: Migratory birds play an important part in the spread of parasites, with more or less impact on resident birds. Previous studies focus on the prevalence of parasites, but changes in infection intensity over time have rarely been studied. As infection intensity can be quantified by qPCR, we measured infection intensity during different seasons, which is important for our understanding of
AimTo analyze the impact of a time-gain selective, first-responder dispatch system on the presence of a shockable initial rhythm (SIR), return of spontaneous circulation (ROSC) and 30-day survival after out-of-hospital cardiac arrest (OHCA).MethodA retrospective observational study comprising OHCA registry data and dispatch data in the Skåne Region, Sweden (2010–2018). Data were categorized accord
This paper reports on a one-to-one relation between articulation and acoustics. It explains how segment boundaries are a result of rapid movements of the articulators. In the acceleration profile, this is identified as peak acceleration, which can be measured. A previous study found that rapid movements of an active articulator - peak acceleration - correlate with the acoustic segment boundary in
