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Single-cell adaptations shape evolutionary transitions to multicellularity in green algae

The evolution of multicellular life has played a pivotal role in shaping biological diversity. However, we know surprisingly little about the natural environmental conditions that favour the formation of multicellular groups. Here we experimentally examine how key environmental factors (predation, nitrogen and water turbulence) combine to influence multicellular group formation in 35 wild unicellu

Sports-Related Traumatic Brain Injury

The speed and intensity of modern sports puts the athlete at risk for impacts to the head, or to the body when the impact force is transmitted to the head. Rapid head rotation caused by these impact forces may lead to a sports-related concussion (SRC), defined as a mild traumatic brain injury, typically resulting in short-lived disturbance of the central nervous system function. The diagnosis of S

Shorter Recovery Time in Concussed Elite Ice Hockey Players by Early Head-and-Neck Cooling : A Clinical Trial

A sports-related concussion (SRC) is most commonly sustained in contact sports, and is defined as a mild traumatic brain injury. An exercise-induced elevation of core body temperature is associated with increased brain temperature that may accelerate secondary injury processes following SRC, and exacerbate the brain injury. In a recent pilot study, acute head-neck cooling of 29 concussed ice hocke

Local and international organizations' co-operation for urban migration policy and urban economics : the case of information centres (BILMER)

Migration has a global impact, but it also intersects with local and nationalissues. In 2020, 281 million people lived outside their country of birth or citizenship, according to the United Nations Global Migration Database. The number of persons displaced across international borders is increasing due to conflict, persecution, and violence. Most of the world’s refugees and asylum seekers live in

Host shift and natural long-distance dispersal to an oceanic island of a host-specific parasite

Parasite dispersal and host-switching may be better understood by knowing when they occurred. We estimated when the ancestor of a parasite of great reed warblers (Acrocephalus arundinaceus) dispersed to the Seychelles and began infecting the endemic Seychelles warbler (A. sechellensis). We used mitochondrial genomes and published molecular divergence rates to estimate the date of divergence betwee

Global Supply Chain Management

Global supply chain management concerns the management of sourcing, manufacturing, and distribution that take place in different countries before a product is sold and delivered to the final buyers. From the view of the focal manufacturing firm, a global supply chain consists of three key parts: the upstream supply network, the manufacturing network of plants belonging to the focal firm, and the d

Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice

Di-n-butyl phthalate (DBP) is a ubiquitous environmental contaminant linked with various adverse health effects, including immune system dysfunction. Gut microbial dysbiosis can contribute to a wide range of pathogenesis, particularly immune disease. Here, we investigated the impact of DBP on the gut microbiome and examined correlations with immune system changes after five weeks oral exposure (10

Assessing efficacy and immune-stimulatory effects of tumor-derived dendritic cell reprogramming using immuno-competent 3D tumor spheroid model

Immunotherapy has brought hope for cancer treatment, but its clinical success remains limited. Recently, overexpression of the transcription factors PU.1, IRF8 and BATF3 (PIB) was shown to induce direct reprogramming of tumor cells into antigen-presenting type 1 conventional dendritic cells (cDC1s), a rare subset of immune cells with pivotal role in anti-cancer immunity. This strategy might open a

A critical typology of "good place branding" : Lessons from place-branding expertise

Place branding is defined as “the development of brands for geographic locationswith the aim of triggering positive associations about the area and distinguishinga place from other places” (Stevens et al., 2020, p. 752). Like all occupations,place branding is organised by discourses, or talk, that determine best practices andnorms about what constitutes expertise (Loacker and Sullivan, 2016). Expl

Formation and photoluminescence of Ge and Si nanoparticles encapsulated in oxide layers

Ge and Si semiconductor nanoparticles encapsulated in oxide layers were prepared by the inert gas condensation method. High-resolution electron microscopy and energy dispersive X-ray spectrometry showed the formation of the core-shell structures with a size below 10 nm. The optical absorption spectra of Ge showed the band edges at higher energy compared to the ordinary Ge element. Photoluminescenc

"Tid är liv – därför bör Skåne införa sms-livräddning nu"

Varje minuts fördröjning av hjärt-lungräddning minskar chansen till överlevnad med 10 procent, skriver åtta forskare vid Centrum för hjärtstopp vid Lunds universitet.Eight researchers at the Lund University Center for Cardiac Arrest write that every minute of delay in cardiopulmonary resuscitation reduces the chance of survival by 10 percent.

Seismic monitoring of strength in stabilized foundations by P-wave reflection and downhole geophysical logging for drill borehole core

Evaluating the subground properties during the initial stage of a construction of building is important in order to estimate the suitability of soil quality to the technical requirements of bearing capacity, resistance to stress, and strength. This study presented the evaluation of the geotechnical properties of soil intended for the construction of Max IV facility of Lund University, performed in

Weather-Related Railway Infrastructure Failures in Sweden: An Exploratory Study

The impacts of adverse weather conditions on railway infrastructure can result in delays and cancellations across the railway network and increased maintenance costs. The frequency and severity of extreme weather events are expected to rise due to climate change, making railways more vulnerable. This study aims to gain a better understanding of weather-related infrastructure failures (specifically

Plasma bioactive adrenomedullin on intensive care unit admission is associated with acute respiratory distress syndrome : an observational study

Background: Bioactive adrenomedullin (bio-ADM) is a vasoactive peptide with a key role in reducing vascular hyperpermeability and improving endothelial stability during infection, but it also has vasodilatory properties. Bioactive ADM has not been studied in conjunction with acute respiratory distress syndrome (ARDS), but it has recently been shown to correlate with outcomes after severe COVID-19.

Sphingosine-1-Phosphate, a Marker of Endothelial Injury and Disease Severity in Preeclampsia

BACKGROUND: Preeclampsia is a hypertensive pregnancy disorder marked by endothelial damage. Healthy endothelium is covered by a protective glycocalyx layer, which, when degraded, releases detectable products into the blood. Sphingosine-1phosphate (S1P) is a cardiovascular biomarker involved in glycocalyx preservation, linked to placentation and preeclampsia development. The study aimed to test the

Routines, Rituals and Reflexes : The Powerful Undercurrents in Everyday Life

Small routines and ingrained cultural reflexes as well as micro-rituals form an often unnoticed or ignored flow in everyday life. They acquire their power by being taken for granted and embodied. In situations of conflict, crisis or change, they may suddenly be noticed and become problematic. This chapter looks at how moves, affect, sensations and stuff interact in the making and unmaking of routi

Active Cognition : Challenges to an Aristotelian Tradition

This edited work draws on a range of contributed expertise to trace the fortune of an Aristotelian thesis over different periods in the history of philosophy. It presents eight cases of direct or indirect challenges to the Aristotelian passive account of human cognition, taking the reader from late antiquity to the 20th century. Chapters analyse the (often indirect) effect of Aristotle’s account o